GB864261A - Manufacture of unsaturated aliphatic-diols - Google Patents
Manufacture of unsaturated aliphatic-diolsInfo
- Publication number
- GB864261A GB864261A GB17444/57A GB1744457A GB864261A GB 864261 A GB864261 A GB 864261A GB 17444/57 A GB17444/57 A GB 17444/57A GB 1744457 A GB1744457 A GB 1744457A GB 864261 A GB864261 A GB 864261A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amino
- resulting
- octadec
- dihydroxy
- diols
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises 1:3-dihydroxy-2-amino-octadec-4-ynes and their acetyl derivatives in the form of their different isomers; threo-1 : 3 dihydroxy-2-amino-octadec-4-enes and their acetyl compounds; erythro-cis-1 : 3-dihydroxy-2-amino-octadec-4-ene and its acetyl compounds and a stereospecific process for the manufacture of 1:3-dihydroxy-2-amino-octadec-4-enes in the form of their different isomers and their acetyl compounds, which comprises condensing hexadec-2-ynal-(1) with b -nitroethanol, reacting the resulting 1 : 3-dihydroxy-2-nitro-octadec-4-yne with an aldehyde, preferably benzaldehyde, reducing the nitro group in the resulting nitro-m-dioxanes, if desired, after isomerization, acetylating, if desired, the resulting amino group, splitting up the dioxane ring and at any stage after the reduction of the nitro group converting the triple bond into a double bond and, if desired, converting the resulting amino-diols into acetyl derivatives or resulting acetyl derivatives into amino-diols, and/or converting the resulting amino-diols into their acid addition salts or salt into the free bases. Nitro groups are preferably reduced by means of aluminium amalgam and reduction of the triple bond by hydrogen in the presence of a Lindlar-catalyst or a palladium catalyst poisoned with quinoline gives cis-compounds whereas with alkali metal and an alcohol or with a dimetal hydride the trans-isomer is obtained. Specification 864,262 is referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH864261X | 1956-06-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB864261A true GB864261A (en) | 1961-03-29 |
Family
ID=4543475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB17444/57A Expired GB864261A (en) | 1956-06-06 | 1957-05-31 | Manufacture of unsaturated aliphatic-diols |
Country Status (3)
| Country | Link |
|---|---|
| CH (1) | CH349592A (en) |
| FR (1) | FR1230430A (en) |
| GB (1) | GB864261A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1171432B (en) * | 1981-08-03 | 1987-06-10 | Fidia Farmaceutici | ORGANIC STARCHES DERIVED FROM NITROGEN LIPIDS USABLE AS DRUGS |
-
1956
- 1956-06-06 CH CH349592D patent/CH349592A/en unknown
-
1957
- 1957-05-31 GB GB17444/57A patent/GB864261A/en not_active Expired
- 1957-06-03 FR FR739983A patent/FR1230430A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH349592A (en) | 1960-10-31 |
| FR1230430A (en) | 1960-09-15 |
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