GB856370A - Improvements in and relating to cinnolines - Google Patents
Improvements in and relating to cinnolinesInfo
- Publication number
- GB856370A GB856370A GB18085/58A GB1808558A GB856370A GB 856370 A GB856370 A GB 856370A GB 18085/58 A GB18085/58 A GB 18085/58A GB 1808558 A GB1808558 A GB 1808558A GB 856370 A GB856370 A GB 856370A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cinnolines
- relating
- alkylmercapto
- antiphlogistic
- aralkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001854 cinnolines Chemical class 0.000 title 1
- -1 cycloaliphatic Chemical group 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 125000000259 cinnolinyl group Chemical class N1=NC(=CC2=CC=CC=C12)* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
The invention comprises 2-acyl-1:3 (2H)-dioxo-1-pyrazolo[a]benzo[c] cinnolines of the general formula: <FORM:0856370/IV(b)/1> or tautomeric forms thereof, and their salts with inorganic or organic bases, wherein R-CO represents the radical of an aliphatic, cycloaliphatic, aromatic, araliphatic or heterocyclic carboxylic acid, which may be substituted, and R1 and R2 represent hydrogen or non-salt-forming substituents (e.g. alkyl, alkoxy, aralkoxy, alkylmercapto or nitro groups or halogen atoms), and the preparation thereof by reacting the corresponding 2-unsubstituted compounds with reactive functional derivatives of carboxylic acids R-COOH. The products have antiphlogistic, antipyretic and analgesic activity.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH856370X | 1957-06-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB856370A true GB856370A (en) | 1960-12-14 |
Family
ID=4542716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB18085/58A Expired GB856370A (en) | 1957-06-07 | 1958-06-06 | Improvements in and relating to cinnolines |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB856370A (en) |
-
1958
- 1958-06-06 GB GB18085/58A patent/GB856370A/en not_active Expired
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