GB836150A - New 3-amino-6-substituted pyridazines and preparation of sulfanilamidopyridazines therefrom - Google Patents
New 3-amino-6-substituted pyridazines and preparation of sulfanilamidopyridazines therefromInfo
- Publication number
- GB836150A GB836150A GB20288/57A GB2028857A GB836150A GB 836150 A GB836150 A GB 836150A GB 20288/57 A GB20288/57 A GB 20288/57A GB 2028857 A GB2028857 A GB 2028857A GB 836150 A GB836150 A GB 836150A
- Authority
- GB
- United Kingdom
- Prior art keywords
- preparation
- formula
- amino
- sulfanilamidopyridazines
- therefrom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises 3-aminopyridazine derivatives of the formula <FORM:0836150/IV (b)/1> wherein R is an alkyl, aryl or aralkyl radical, and their preparation by reacting a 3-amino-6halo-pyridazine with the reaction product of an alkali metal, e.g. sodium, and an alcohol of the formula ROH, the reaction being preferably carried out either in an excess of the alcohol ROH or in an inert organic solvent, at a temperature of 50-200 DEG C. The invention also comprises a process for the preparation of sulphanilamido pyridazines of the formula <FORM:0836150/IV (b)/2> by reacting p-acetylsulphanilyl halide with a compound of the formula I in an organic solvent which is preferably a tertiary amine at a preferred temperature between 20 DEG and 100 DEG C., and deacetylating the resulting acetyl compound, for example, by hydrolysis with a strong base. Examples describe the preparation of 6-methoxy-, 6-n-hexyloxy-, 6-phenoxyand 6 - benzyloxy - 3 - amino - pyridazine and their conversion to the corresponding p-acetylsulphanilyl- and sulphanilyl-derivatives. Specification 776,730 is referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US836150XA | 1956-07-09 | 1956-07-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB836150A true GB836150A (en) | 1960-06-01 |
Family
ID=22179525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB20288/57A Expired GB836150A (en) | 1956-07-09 | 1957-06-27 | New 3-amino-6-substituted pyridazines and preparation of sulfanilamidopyridazines therefrom |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB836150A (en) |
| MY (1) | MY6200001A (en) |
-
1957
- 1957-06-27 GB GB20288/57A patent/GB836150A/en not_active Expired
-
1962
- 1962-12-31 MY MY6200001A patent/MY6200001A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MY6200001A (en) | 1962-12-31 |
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