GB834517A - Radiopaque compositions - Google Patents
Radiopaque compositionsInfo
- Publication number
- GB834517A GB834517A GB2944758A GB2944758A GB834517A GB 834517 A GB834517 A GB 834517A GB 2944758 A GB2944758 A GB 2944758A GB 2944758 A GB2944758 A GB 2944758A GB 834517 A GB834517 A GB 834517A
- Authority
- GB
- United Kingdom
- Prior art keywords
- present
- weight
- polyethylene glycol
- radiopaque
- triton
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0461—Dispersions, colloids, emulsions or suspensions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
Radiopaque compositions comprise suspensions of finely divided, substantially insoluble, radiopaque substances in water containing a polyethylene glycol as thickening agent, and a small quantity of a pharmacologically acceptable surface active agent. The radiopaque substance is preferably present to an extent of at least 50% and up to 90% by weight. Examples are barium sulphate, zirconium oxide, propyl 3,5 - diiodo - 4 - pyridone - N - acetate; ethyl 3,5 - diacetamido - 2,4,6 - triiodobenzoate. The polyethylene glycol may have a molecular weight of from 400 to 20,000 (preferably about 2000 to 10,000), polyethylene glycol 6000 being especially preferred, and may be present in amounts of from 1 to 20% (preferably 5 to 10%) by weight. The surface active agent may be present to an extent of from about 0.01 to 0.5% (preferably 0.1 to 0.3%) by weight, its nature being uncritical provided it is non-toxic in the amounts used. Examples are those marketed under the Registered Trade Marks "Triton" and "Tween", e.g. Triton WR-1339 and Tween 20 and 80. Buffering agents may also be present.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2944758A GB834517A (en) | 1958-09-15 | 1958-09-15 | Radiopaque compositions |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2944758A GB834517A (en) | 1958-09-15 | 1958-09-15 | Radiopaque compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
GB834517A true GB834517A (en) | 1960-05-11 |
Family
ID=10291708
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2944758A Expired GB834517A (en) | 1958-09-15 | 1958-09-15 | Radiopaque compositions |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB834517A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1980001244A1 (en) * | 1978-12-19 | 1980-06-26 | Bykgulden Lomberg Chem Fab | X-ray contrast media solutions |
EP0012926A1 (en) * | 1978-12-19 | 1980-07-09 | Byk Gulden Lomberg Chemische Fabrik GmbH | Solutions of X-ray contrast agents |
FR2548022A1 (en) * | 1983-06-30 | 1985-01-04 | Ispytatelny Inst Med | COMPOSITION FOR EMBOLIZATION OF BLOOD VESSELS CONTAINING POLYMERIC MATERIAL AS EMBOLIZING MATERIAL |
-
1958
- 1958-09-15 GB GB2944758A patent/GB834517A/en not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1980001244A1 (en) * | 1978-12-19 | 1980-06-26 | Bykgulden Lomberg Chem Fab | X-ray contrast media solutions |
EP0012926A1 (en) * | 1978-12-19 | 1980-07-09 | Byk Gulden Lomberg Chemische Fabrik GmbH | Solutions of X-ray contrast agents |
FR2548022A1 (en) * | 1983-06-30 | 1985-01-04 | Ispytatelny Inst Med | COMPOSITION FOR EMBOLIZATION OF BLOOD VESSELS CONTAINING POLYMERIC MATERIAL AS EMBOLIZING MATERIAL |
GB2144327A (en) * | 1983-06-30 | 1985-03-06 | Vnii Ispytatel Med Tech | Composition for the embolization of blood vessels/radiopaques |
US4999188A (en) * | 1983-06-30 | 1991-03-12 | Solodovnik Valentin D | Methods for embolization of blood vessels |
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