GB827442A - Glycerol fatty acid partial ester gels - Google Patents
Glycerol fatty acid partial ester gelsInfo
- Publication number
- GB827442A GB827442A GB7172/58A GB717258A GB827442A GB 827442 A GB827442 A GB 827442A GB 7172/58 A GB7172/58 A GB 7172/58A GB 717258 A GB717258 A GB 717258A GB 827442 A GB827442 A GB 827442A
- Authority
- GB
- United Kingdom
- Prior art keywords
- fatty acids
- partial ester
- fatty
- fatty acid
- monoglycerides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A gel-like base for use as a carrier in making medicaments, consists of a glycerol fatty acid partial ester composition in which 10 to 90% by wt. of water is incorporated, the partial ester composition containing at least 75% of monoglycerides of fatty acids, preferably unsaturated, which contain at least 16 C atoms, and in which there is present not more than 10% of saturated fatty acid glycerides having more than 11 C atoms. Mono-olein, mono-linolein, and monolinolenin are especially suitable, and are obtained from fatty oils, e.g. cottonseed, poppyseed or linseed oil. The crude fatty acids obtained from the fatty oil are dissolved in acetone and chilled to separate out the major part of palmitic and other saturated higher fatty acids, and the resulting fatty acids, mainly oleic and linoleic acid, are then reacted with the required amount of glycerine or a tri-glyceride in the presence of an inter-esterification catalyst to form the monoglyceride. This is separated by thin film centrifugal distillation under reduced pressure, as described in Specifications 682,625 and 682,626, [Group IV (b)]. The product containing 75 to 90% of monoglycerides is capable of absorbing up to 90% of water by mixing and heating to form a clear gel to which vitamins, hormones, or enzymes may be added.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US827442XA | 1957-04-19 | 1957-04-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB827442A true GB827442A (en) | 1960-02-03 |
Family
ID=22173162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7172/58A Expired GB827442A (en) | 1957-04-19 | 1958-03-06 | Glycerol fatty acid partial ester gels |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB827442A (en) |
-
1958
- 1958-03-06 GB GB7172/58A patent/GB827442A/en not_active Expired
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