GB785683A - Cyclopentanopolyhydrophenanthrene compounds - Google Patents

Cyclopentanopolyhydrophenanthrene compounds

Info

Publication number
GB785683A
GB785683A GB9553/56A GB955356A GB785683A GB 785683 A GB785683 A GB 785683A GB 9553/56 A GB9553/56 A GB 9553/56A GB 955356 A GB955356 A GB 955356A GB 785683 A GB785683 A GB 785683A
Authority
GB
United Kingdom
Prior art keywords
keto
convertible
acid hydrolysis
group
iodine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB9553/56A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB785683A publication Critical patent/GB785683A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises compounds having the formula: <FORM:0785683/IV (a)/1> in which the 3-position is occupied either by a bivalent group convertible to keto by acid hydrolysis, e.g. a cyclic acetal or by a pair of univalent groups together convertible to a single keto group by acid hydrolysis, e.g. a non-cyclic acetal and of the formula: <FORM:0785683/IV (a)/2> in which the 3-position is occupied by a univalent group which is convertible to keto by acid hydrolysis, e.g. an enol ether and their preparation from the corresponding 3-substituted-11-keto-etienoylpyruvic acid by reaction with iodine. The reaction may be effected by bringing a buffered aqueous solution of the starting compound, e.g. with disodium phosphate, into intimate contact with iodine. An example discloses the production of d and dl - 3 - ethylenedioxy - 11,20 - diketo - 21 - iodopregnene. Specifications 763,208 and 785,684 are referred to.
GB9553/56A 1952-09-17 1953-09-16 Cyclopentanopolyhydrophenanthrene compounds Expired GB785683A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US785683XA 1952-09-17 1952-09-17

Publications (1)

Publication Number Publication Date
GB785683A true GB785683A (en) 1957-11-06

Family

ID=22144871

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9553/56A Expired GB785683A (en) 1952-09-17 1953-09-16 Cyclopentanopolyhydrophenanthrene compounds

Country Status (1)

Country Link
GB (1) GB785683A (en)

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