GB733992A - Process for the preparation of 4-(p-aminobenzenesulphonamido) pyrimidines - Google Patents
Process for the preparation of 4-(p-aminobenzenesulphonamido) pyrimidinesInfo
- Publication number
- GB733992A GB733992A GB32973/53A GB3297353A GB733992A GB 733992 A GB733992 A GB 733992A GB 32973/53 A GB32973/53 A GB 32973/53A GB 3297353 A GB3297353 A GB 3297353A GB 733992 A GB733992 A GB 733992A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amino
- pyrimidine
- aminobenzenesulphonamido
- substituent
- amino group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PXDBUWPMANSAFI-UHFFFAOYSA-N 4-amino-n-pyrimidin-4-ylbenzenesulfonamide Chemical class C1=CC(N)=CC=C1S(=O)(=O)NC1=CC=NC=N1 PXDBUWPMANSAFI-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 6
- 125000003277 amino group Chemical group 0.000 abstract 3
- 125000001424 substituent group Chemical group 0.000 abstract 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- -1 benzene sulphonyl halide Chemical class 0.000 abstract 2
- 239000011230 binding agent Substances 0.000 abstract 2
- 230000005494 condensation Effects 0.000 abstract 2
- 238000009833 condensation Methods 0.000 abstract 2
- DAZXVJBJRMWXJP-UHFFFAOYSA-N n,n-dimethylethylamine Chemical compound CCN(C)C DAZXVJBJRMWXJP-UHFFFAOYSA-N 0.000 abstract 2
- OYRRZWATULMEPF-UHFFFAOYSA-N pyrimidin-4-amine Chemical compound NC1=CC=NC=N1 OYRRZWATULMEPF-UHFFFAOYSA-N 0.000 abstract 2
- MAUMSNABMVEOGP-UHFFFAOYSA-N (methyl-$l^{2}-azanyl)methane Chemical compound C[N]C MAUMSNABMVEOGP-UHFFFAOYSA-N 0.000 abstract 1
- OSZFJGLXXUAMEJ-UHFFFAOYSA-N 2-acetyl-4-aminobenzenesulfonyl chloride Chemical compound CC(=O)C1=CC(N)=CC=C1S(Cl)(=O)=O OSZFJGLXXUAMEJ-UHFFFAOYSA-N 0.000 abstract 1
- VNQBDDXIHRUBIO-UHFFFAOYSA-N 4,6-bis(benzenesulfonyl)pyrimidin-2-amine Chemical compound C1(=CC=CC=C1)S(=O)(=O)C1=CC(=NC(=N1)N)S(=O)(=O)C1=CC=CC=C1 VNQBDDXIHRUBIO-UHFFFAOYSA-N 0.000 abstract 1
- DJEQZVQFEPKLOY-UHFFFAOYSA-N N,N-dimethylbutylamine Chemical compound CCCCN(C)C DJEQZVQFEPKLOY-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- ZUHZZVMEUAUWHY-UHFFFAOYSA-N n,n-dimethylpropan-1-amine Chemical compound CCCN(C)C ZUHZZVMEUAUWHY-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/69—Benzenesulfonamido-pyrimidines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE317303X | 1952-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB733992A true GB733992A (en) | 1955-07-20 |
Family
ID=6150739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB32973/53A Expired GB733992A (en) | 1952-12-22 | 1953-11-27 | Process for the preparation of 4-(p-aminobenzenesulphonamido) pyrimidines |
Country Status (4)
| Country | Link |
|---|---|
| CH (1) | CH317303A (enrdf_load_stackoverflow) |
| FR (1) | FR1089732A (enrdf_load_stackoverflow) |
| GB (1) | GB733992A (enrdf_load_stackoverflow) |
| NL (1) | NL84581C (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2792391A (en) * | 1954-06-15 | 1957-05-14 | Ciba Pharm Prod Inc | Process for the manufacture of sulfonamides |
-
0
- NL NL84581D patent/NL84581C/xx active
-
1953
- 1953-09-01 CH CH317303D patent/CH317303A/de unknown
- 1953-11-27 GB GB32973/53A patent/GB733992A/en not_active Expired
- 1953-12-18 FR FR1089732D patent/FR1089732A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL84581C (enrdf_load_stackoverflow) | |
| FR1089732A (fr) | 1955-03-21 |
| CH317303A (de) | 1956-11-15 |
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