GB730243A - - Google Patents
Info
- Publication number
- GB730243A GB730243A GB730243DA GB730243A GB 730243 A GB730243 A GB 730243A GB 730243D A GB730243D A GB 730243DA GB 730243 A GB730243 A GB 730243A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyridyl
- methane
- hydroxyphenyl
- hydroxy
- condensation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 6
- 230000005494 condensation Effects 0.000 abstract 4
- 238000009833 condensation Methods 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- 125000004423 acyloxy group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000002576 ketones Chemical class 0.000 abstract 3
- -1 pyridine aldehydes Chemical class 0.000 abstract 3
- JJYPMNFTHPTTDI-UHFFFAOYSA-N 3-methylaniline Chemical compound CC1=CC=CC(N)=C1 JJYPMNFTHPTTDI-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- WTEOIRVLGSZEPR-UHFFFAOYSA-N boron trifluoride Chemical compound FB(F)F WTEOIRVLGSZEPR-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 2
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 abstract 2
- ZWWZMKBVXNDVEA-UHFFFAOYSA-N 2-[bis(4-methoxyphenyl)methyl]pyridine Chemical compound C1=CC(OC)=CC=C1C(C=1N=CC=CC=1)C1=CC=C(OC)C=C1 ZWWZMKBVXNDVEA-UHFFFAOYSA-N 0.000 abstract 1
- ZXFYOCPABYMOTJ-UHFFFAOYSA-N 2-benzyl-4-[(3-benzyl-4-hydroxyphenyl)-pyridin-2-ylmethyl]phenol Chemical compound OC1=C(C=C(C=C1)C(C1=NC=CC=C1)C1=CC(=C(C=C1)O)CC1=CC=CC=C1)CC1=CC=CC=C1 ZXFYOCPABYMOTJ-UHFFFAOYSA-N 0.000 abstract 1
- PBBZKNKAIHWEMP-UHFFFAOYSA-N 4-[(4-aminophenyl)-pyridin-2-ylmethyl]aniline Chemical compound NC1=CC=C(C=C1)C(C1=NC=CC=C1)C1=CC=C(C=C1)N PBBZKNKAIHWEMP-UHFFFAOYSA-N 0.000 abstract 1
- OIMWUXSITXMEFP-UHFFFAOYSA-N 4-[(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-pyridin-2-ylmethyl]-5-methyl-2-propan-2-ylphenol Chemical compound OC1=C(C=C(C(=C1)C)C(C1=NC=CC=C1)C1=CC(=C(C=C1C)O)C(C)C)C(C)C OIMWUXSITXMEFP-UHFFFAOYSA-N 0.000 abstract 1
- ACSYLJKDVLRRLQ-UHFFFAOYSA-N 4-[(4-hydroxy-2-methylphenyl)-pyridin-2-ylmethyl]-3-methylphenol Chemical compound OC1=CC(=C(C=C1)C(C1=NC=CC=C1)C1=C(C=C(C=C1)O)C)C ACSYLJKDVLRRLQ-UHFFFAOYSA-N 0.000 abstract 1
- XIMRVMOVSLWRHI-UHFFFAOYSA-N 4-[(4-hydroxy-3-methoxyphenyl)-pyridin-2-ylmethyl]-2-methoxyphenol Chemical compound OC1=C(C=C(C=C1)C(C1=NC=CC=C1)C1=CC(=C(C=C1)O)OC)OC XIMRVMOVSLWRHI-UHFFFAOYSA-N 0.000 abstract 1
- LWGYJJFGHPSBRI-UHFFFAOYSA-N 4-[(4-hydroxy-3-methylphenyl)-pyridin-2-ylmethyl]-2-methylphenol Chemical compound OC1=C(C=C(C=C1)C(C1=NC=CC=C1)C1=CC(=C(C=C1)O)C)C LWGYJJFGHPSBRI-UHFFFAOYSA-N 0.000 abstract 1
- CPGWWNCSUYIHPC-UHFFFAOYSA-N 4-[(4-hydroxy-3-phenylphenyl)-pyridin-2-ylmethyl]-2-phenylphenol Chemical compound OC1=C(C=C(C=C1)C(C1=NC=CC=C1)C1=CC(=C(C=C1)O)C1=CC=CC=C1)C1=CC=CC=C1 CPGWWNCSUYIHPC-UHFFFAOYSA-N 0.000 abstract 1
- WOEGUIKGYBZBFD-UHFFFAOYSA-N 4-[(4-hydroxyphenyl)-(6-methylpyridin-2-yl)methyl]phenol Chemical compound OC1=CC=C(C=C1)C(C1=NC(=CC=C1)C)C1=CC=C(C=C1)O WOEGUIKGYBZBFD-UHFFFAOYSA-N 0.000 abstract 1
- YEFDAKBOLSLYFU-UHFFFAOYSA-N 4-[(4-hydroxyphenyl)-phenyl-pyridin-2-ylmethyl]phenol Chemical compound OC1=CC=C(C=C1)C(C1=CC=CC=C1)(C1=NC=CC=C1)C1=CC=C(C=C1)O YEFDAKBOLSLYFU-UHFFFAOYSA-N 0.000 abstract 1
- LJROKJGQSPMTKB-UHFFFAOYSA-N 4-[(4-hydroxyphenyl)-pyridin-2-ylmethyl]phenol Chemical compound C1=CC(O)=CC=C1C(C=1N=CC=CC=1)C1=CC=C(O)C=C1 LJROKJGQSPMTKB-UHFFFAOYSA-N 0.000 abstract 1
- GHMFBXLEROLLRP-UHFFFAOYSA-N 4-[(4-hydroxyphenyl)-pyridin-3-ylmethyl]phenol Chemical compound C1=CC(O)=CC=C1C(C=1C=NC=CC=1)C1=CC=C(O)C=C1 GHMFBXLEROLLRP-UHFFFAOYSA-N 0.000 abstract 1
- HRQXTHWSVIKOLP-UHFFFAOYSA-N 4-[(4-hydroxyphenyl)-pyridin-4-ylmethyl]phenol Chemical compound C1=CC(O)=CC=C1C(C=1C=CC(O)=CC=1)C1=CC=NC=C1 HRQXTHWSVIKOLP-UHFFFAOYSA-N 0.000 abstract 1
- 229910015900 BF3 Inorganic materials 0.000 abstract 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical class OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 229910021627 Tin(IV) chloride Inorganic materials 0.000 abstract 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 abstract 1
- 150000001299 aldehydes Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000004982 aromatic amines Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012024 dehydrating agents Substances 0.000 abstract 1
- 239000000645 desinfectant Substances 0.000 abstract 1
- 239000012954 diazonium Substances 0.000 abstract 1
- 150000001989 diazonium salts Chemical class 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000008141 laxative Substances 0.000 abstract 1
- 229940125722 laxative agent Drugs 0.000 abstract 1
- VMPITZXILSNTON-UHFFFAOYSA-N o-anisidine Chemical compound COC1=CC=CC=C1N VMPITZXILSNTON-UHFFFAOYSA-N 0.000 abstract 1
- 150000002989 phenols Chemical class 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 239000001632 sodium acetate Substances 0.000 abstract 1
- 235000017281 sodium acetate Nutrition 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- HPGGPRDJHPYFRM-UHFFFAOYSA-J tin(iv) chloride Chemical compound Cl[Sn](Cl)(Cl)Cl HPGGPRDJHPYFRM-UHFFFAOYSA-J 0.000 abstract 1
- 239000008096 xylene Substances 0.000 abstract 1
- 239000011592 zinc chloride Substances 0.000 abstract 1
- 235000005074 zinc chloride Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB730243A true GB730243A (enrdf_load_stackoverflow) |
Family
ID=1751224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB730243D Active GB730243A (enrdf_load_stackoverflow) |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB730243A (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2014255A1 (enrdf_load_stackoverflow) * | 1968-06-26 | 1970-04-17 | Hoechst Ag | |
| WO1980000414A1 (en) * | 1978-08-28 | 1980-03-20 | R Clayton | Colon cleansing system and technique |
| FR2459232A1 (fr) * | 1979-06-14 | 1981-01-09 | Lpb Ist Farm | Le bis-(p-(1-ethoxy-ethoxy)phenyl)-2-pyridylmethane, son procede de preparation et son application en therapeutique |
-
0
- GB GB730243D patent/GB730243A/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2014255A1 (enrdf_load_stackoverflow) * | 1968-06-26 | 1970-04-17 | Hoechst Ag | |
| WO1980000414A1 (en) * | 1978-08-28 | 1980-03-20 | R Clayton | Colon cleansing system and technique |
| FR2459232A1 (fr) * | 1979-06-14 | 1981-01-09 | Lpb Ist Farm | Le bis-(p-(1-ethoxy-ethoxy)phenyl)-2-pyridylmethane, son procede de preparation et son application en therapeutique |
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