GB668850A - Improved process for producing laevulose-containing solutions for injection purposes - Google Patents

Improved process for producing laevulose-containing solutions for injection purposes

Info

Publication number
GB668850A
GB668850A GB574149A GB574149A GB668850A GB 668850 A GB668850 A GB 668850A GB 574149 A GB574149 A GB 574149A GB 574149 A GB574149 A GB 574149A GB 668850 A GB668850 A GB 668850A
Authority
GB
United Kingdom
Prior art keywords
inulin
acids
laevulose
lμvulose
under pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB574149A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
COFFAROM AG
Original Assignee
COFFAROM AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH277825D priority Critical patent/CH277825A/en
Priority to DEP34117A priority patent/DE845835C/en
Application filed by COFFAROM AG filed Critical COFFAROM AG
Priority to GB574149A priority patent/GB668850A/en
Publication of GB668850A publication Critical patent/GB668850A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K11/00—Fructose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

668,850. Laevulose; medicinal preparations. ABBEY, A. (Coffarom Akt.-Ges.). March 2, 1949, No. 5741/49. Classes 81 (i) and 127. Lµvulose solutions suitable for intravenous injection are prepared by hydrolysing inulin in aqueous solution under pressure and/or in the presence of acids; the inulin being purified to a pharmaceutical purity, e.g. by repeated recrystallisation and precipitation by organic precipitants such as alcohol, the pharmaceutically pure inulin being hydrolysed, and the resulting lµvulose-containing solution being sterilized, if desired decolourised and filtered, and filled into ampoules. The acids employed may be lactic, gluconic, ketogulonic, or ascorbic acids, and may be subsequently neutralised with sodium or calcium hydroxide. Or a volatile organic acid such as formic acid, or carbon dioxide under pressure, may be used and subsequently removed. Medicines such as k-strophanthin, caffeine citrate or glucosides may be added to the solution before sterilization. Specifications 272,876 and 8898/05, [both in, Class 127], are referred to.
GB574149A 1949-02-15 1949-03-02 Improved process for producing laevulose-containing solutions for injection purposes Expired GB668850A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CH277825D CH277825A (en) 1949-03-02 1949-02-05 Process for the preparation of injection solutions containing levulose.
DEP34117A DE845835C (en) 1949-02-15 1949-02-15 Process for the preparation of injection solutions containing laevulose
GB574149A GB668850A (en) 1949-03-02 1949-03-02 Improved process for producing laevulose-containing solutions for injection purposes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB574149A GB668850A (en) 1949-03-02 1949-03-02 Improved process for producing laevulose-containing solutions for injection purposes

Publications (1)

Publication Number Publication Date
GB668850A true GB668850A (en) 1952-03-26

Family

ID=9801776

Family Applications (1)

Application Number Title Priority Date Filing Date
GB574149A Expired GB668850A (en) 1949-02-15 1949-03-02 Improved process for producing laevulose-containing solutions for injection purposes

Country Status (2)

Country Link
CH (1) CH277825A (en)
GB (1) GB668850A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2990327A (en) * 1960-07-14 1961-06-27 Synergistics Inc Composition and method for treating biliary dyskinesia

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2459046A1 (en) * 1979-06-15 1981-01-09 Griffon Henri PROCESS FOR THE PREPARATION OF STABLE AQUEOUS SOLUTIONS OF ALLOXANE AND RESULTING SOLUTIONS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2990327A (en) * 1960-07-14 1961-06-27 Synergistics Inc Composition and method for treating biliary dyskinesia

Also Published As

Publication number Publication date
CH277825A (en) 1951-09-15

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