GB663553A - Improvements in or relating to choleretic agents and methods of making same - Google Patents

Improvements in or relating to choleretic agents and methods of making same

Info

Publication number
GB663553A
GB663553A GB28176/48A GB2817648A GB663553A GB 663553 A GB663553 A GB 663553A GB 28176/48 A GB28176/48 A GB 28176/48A GB 2817648 A GB2817648 A GB 2817648A GB 663553 A GB663553 A GB 663553A
Authority
GB
United Kingdom
Prior art keywords
fluoranthoyl
fluoranthene
condensing
preparation
anhydride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28176/48A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of GB663553A publication Critical patent/GB663553A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/86—Unsaturated compounds containing keto groups containing six-membered aromatic rings and other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Synthetic choleritic agents are obtained by condensing in presence of aluminium chloride, 1 : 2 : 3 : 4-tetrahydrofluoranthene with succinic anhydride, to give compounds of the formula Ar-CO(CH2)2COOH, in which Ar is fluoranthene, the attached group taking up either the 5- or 13-position, the sodium salts being especially effective. An example describes the preparation by this method of b -1 : 2 : 3 : 4-fluoranthoyl propionic acid in the 2 isomeric forms. The 2 isomers may be converted into the methyl esters, and separated, or by crystallization from alcohol. The Specification as open to inspection under Sect. 91 comprises also the preparation of similar products by condensing the above compound also with glutaric anhydride; fluoranthene and dibenzofurane with either acid anhydride and the reduction of the fluoranthoyl and similar condensation products to fluoranthyl or corresponding reduced compounds with Zn/Hg and hydrochloric acid. This subject-matter does not appear in the Specification as accepted.
GB28176/48A 1948-02-26 1948-10-29 Improvements in or relating to choleretic agents and methods of making same Expired GB663553A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US663553XA 1948-02-26 1948-02-26

Publications (1)

Publication Number Publication Date
GB663553A true GB663553A (en) 1951-12-27

Family

ID=22068966

Family Applications (1)

Application Number Title Priority Date Filing Date
GB28176/48A Expired GB663553A (en) 1948-02-26 1948-10-29 Improvements in or relating to choleretic agents and methods of making same

Country Status (1)

Country Link
GB (1) GB663553A (en)

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