GB635876A - Process for the production of 2-(ú-amino-benzene-sulphonylamino)-pyrimidines - Google Patents
Process for the production of 2-(ú-amino-benzene-sulphonylamino)-pyrimidinesInfo
- Publication number
- GB635876A GB635876A GB5369/48A GB536948A GB635876A GB 635876 A GB635876 A GB 635876A GB 5369/48 A GB5369/48 A GB 5369/48A GB 536948 A GB536948 A GB 536948A GB 635876 A GB635876 A GB 635876A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aminobenzene
- pyrimidine
- sulphonylamino
- sulphonamide
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/69—Benzenesulfonamido-pyrimidines
Abstract
2-(p-Aminobenzene-sulphonylamino)-pyrimidine is made by heating together a p-aminobenzene-sulphonamide or a corresponding compound having in the p-position a group convertible into an amino group and a compound of the formula XNHR in which X is a substituent acidifying the adjacent NH group and R is a substituted or unsubstituted pyrimidine ring. X may be a nitro, carboxyl, acyl or cyano group. In examples: (1) 2-nitroamino-pyrimidine and p-aminobenzene-sulphonamide are fused together in the presence of a few drops of concentrated hydrochloric acid to give 2-(p-aminobenzene-sulphonylamino)-pyrimidine; (2) a mixture of p-aminobenzene-sulphonamide and 2 - nitroamino - 4 - methyl-pyrimidine is added to molten p-aminobenzene-sulphonamide to give 2 - (p - aminobenzene-sulphonylamino) - 4 - methyl - pyrimidine; (3) 2-nitroamino-4,6-dimethyl-pyrimidine is added to molten p-aminobenzene-sulphonamide to give 2-(p-aminobenzene-sulphonylamino)-4,6-dimethyl - pyrimidine; (4) 2 - cyanamino - 4 - methyl-pyrimidine is added to a fused mixture of p-aminobenzene-sulphonamide and its sodium salt to give a mixture of 2-(p-aminobenzene-sulphonylamino)-4-methyl-pyrimidine and p-aminobenzene-sulphonyl-guanidine; and (5) 2-cyanamino-4,6-dimethyl-pyrimidine is added to a molten mixture of p-aminobenzene-sulphonamide and its hydrochloride to give a mixture of 2-(p-aminobenzene-sulphonylamino)-4,6-dimethyl-pyrimidine and p-aminobenzene-sulphonyl-guanidine.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS635876X | 1947-11-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB635876A true GB635876A (en) | 1950-04-19 |
Family
ID=5454155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5369/48A Expired GB635876A (en) | 1947-11-14 | 1948-02-23 | Process for the production of 2-(ú-amino-benzene-sulphonylamino)-pyrimidines |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB635876A (en) |
-
1948
- 1948-02-23 GB GB5369/48A patent/GB635876A/en not_active Expired
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