GB521575A - Process for the preparation of amino-alkoxy-diphenyl derivatives - Google Patents

Process for the preparation of amino-alkoxy-diphenyl derivatives

Info

Publication number
GB521575A
GB521575A GB3407738A GB3407738A GB521575A GB 521575 A GB521575 A GB 521575A GB 3407738 A GB3407738 A GB 3407738A GB 3407738 A GB3407738 A GB 3407738A GB 521575 A GB521575 A GB 521575A
Authority
GB
United Kingdom
Prior art keywords
diphenyl
prepared
hydroxydiphenyl
reacting
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3407738A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB3407738A priority Critical patent/GB521575A/en
Publication of GB521575A publication Critical patent/GB521575A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

521,575. Diphenyl derivatives. ELLIS, L. S. E. (Soc. des Usines Chimiques Rhone- Poulenc). Nov. 23, 1938, No. 34077. [Class 2 (iii)] Aminoalkoxy derivatives of diphenyl of the formula in which Rand R<SP>1</SP> represent hydrogen or alkyl or together signify a polymethylene chain, are prepared by (1) treating an alkali metal compound of a hydroxydiphenyl with a chloralkylamine, or (2) first reacting the same alkali metal compoundwith an alkylene dihalide, and treating the product with ammonia, a mono- or di-alkylamine, or a cyclic amine. The products possess therapeutic properties. According to the examples, (1) diethylaminoethoxy-, piperidinoethoxy- and diethylaminopropoxy-2- diphenyl are prepared by reacting 2-hydroxydiphenyl with 1-chlor-2-diethylaminoethane, chlorethylpiperidine and 1-chlor-3-diethylaminopropane respectively in presence of sodium alcoholate ; diethylaminoethoxy-3 and 4- diphenyl are similarly prepared ; (2) dimethylaminoethoxy-2-diphenyl is obtained by treating 2-hydroxydiphenyl with ethylene dibromide in the presence of sodium alcoholate and reacting the 2-bromethoxydiphenyl so formed with dimethylamine ; similar products are prepared by replacing the dimethylamine by ammonia or ethylamine or by using trimethylene dibromide instead of ethylene dibromide. Specification 484,906 is referred to.
GB3407738A 1938-11-23 1938-11-23 Process for the preparation of amino-alkoxy-diphenyl derivatives Expired GB521575A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3407738A GB521575A (en) 1938-11-23 1938-11-23 Process for the preparation of amino-alkoxy-diphenyl derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3407738A GB521575A (en) 1938-11-23 1938-11-23 Process for the preparation of amino-alkoxy-diphenyl derivatives

Publications (1)

Publication Number Publication Date
GB521575A true GB521575A (en) 1940-05-24

Family

ID=10361097

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3407738A Expired GB521575A (en) 1938-11-23 1938-11-23 Process for the preparation of amino-alkoxy-diphenyl derivatives

Country Status (1)

Country Link
GB (1) GB521575A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2443796A (en) * 1943-08-11 1948-06-22 Geigy Ag J R Diethylamino ethyl ether of dhsopropyl carbine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2443796A (en) * 1943-08-11 1948-06-22 Geigy Ag J R Diethylamino ethyl ether of dhsopropyl carbine

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