GB430282A - The manufacture of new alkylated 5:5-phenylethyl-hydantoins - Google Patents
The manufacture of new alkylated 5:5-phenylethyl-hydantoinsInfo
- Publication number
- GB430282A GB430282A GB2345934A GB2345934A GB430282A GB 430282 A GB430282 A GB 430282A GB 2345934 A GB2345934 A GB 2345934A GB 2345934 A GB2345934 A GB 2345934A GB 430282 A GB430282 A GB 430282A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzyl
- hydantoin
- methyl
- phenylethyl
- chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Phenyl ethyl hydantoins having a methyl group attached to one nitrogen atom and a benzyl or substituted benzyl group attached to the other nitrogen atom are prepared by methylating or benzylating the corresponding mono-substituted hydantoin by means of suitable agents such as methyl chloride, dimethyl sulphate, benzyl chloride and nitrobenzyl chloride. The reaction is preferably effected in the presence of a solvent or diluent and of an acid-binding substance. In examples (1) 3 - benzyl - 5 - 5 phenyl ethyl hydantoin obtained by benzylating the phenylethyl hydantoin, is dissolved in hot ethanol, and caustic soda is added; the mixture is then treated with dimethyl sulphate at 55--75 DEG C. with stirring. (2) 1 - Benzyl - 5 - 5 - phenylethyl hydantoin, obtained by treating phenylethylbenzylureidoacetonitrile with an acid, is dissolved in aqueous caustic soda, and treated with dimethyl sulphate at 50 DEG C. with stirring. Alternatively the starting compound may be N-methyl or N-benzyl-5-phenyl hydantoin, the N - methyl - N - benzyl derivative being then ethylated to produce the 5-5-phenyl ethyl derivative.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2345934A GB430282A (en) | 1933-12-15 | 1933-12-15 | The manufacture of new alkylated 5:5-phenylethyl-hydantoins |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2345934A GB430282A (en) | 1933-12-15 | 1933-12-15 | The manufacture of new alkylated 5:5-phenylethyl-hydantoins |
Publications (1)
Publication Number | Publication Date |
---|---|
GB430282A true GB430282A (en) | 1935-06-17 |
Family
ID=10195962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2345934A Expired GB430282A (en) | 1933-12-15 | 1933-12-15 | The manufacture of new alkylated 5:5-phenylethyl-hydantoins |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB430282A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3209009A (en) * | 1965-09-28 | Pons ctal |
-
1933
- 1933-12-15 GB GB2345934A patent/GB430282A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3209009A (en) * | 1965-09-28 | Pons ctal |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB430282A (en) | The manufacture of new alkylated 5:5-phenylethyl-hydantoins | |
Cook et al. | 50. Studies in the azole series. Part III. The interaction of aminoacetonitrile and carbon disulphide | |
GOLUMBIC et al. | CHEMICAL REACTIONS OF THE NITROGEN MUSTARD GASES. 1 II. THE COMPOSITION OF AGED UNBUFFERED SOLUTIONS OF METHYL-BIS (β-CHLOROETHYL) AMINE | |
SU433680A3 (en) | ||
GB856409A (en) | Improvements in and relating to a new pyridazine derivative and its process of preparation | |
US2265207A (en) | D-lysergic acid - d - l-bjtdroxybutyl | |
SU604497A3 (en) | Method of preparing tetramyzole or salts thereof | |
Cambron et al. | The oxidation of xanthates and some new dialkyl sulphur-and disulphur-dicarbothionates | |
Hodgson et al. | 260. The replacement of the diazonium by the nitro-group. Part III. Decompositions by cupro-cupri sulphite | |
GB986579A (en) | 5-ethylidene dibenzocycloheptadienes and the preparation thereof | |
GB796996A (en) | Imidazole derivatives | |
GB1070139A (en) | Novel imidazothiazole derivatives and a process for preparation thereof | |
US2616895A (en) | Iminodibenzyl derivative | |
GB672164A (en) | A process for the manufacture of pentaenes | |
US3239526A (en) | 3-phenyl-4-aminocinnolines | |
GB937879A (en) | New pyrazole-carboxylic acid hydrazides | |
GB679894A (en) | Production of thiosemicarbazones | |
GB934577A (en) | Preparation of 3-(trifluoromethyl)-phenols | |
US2086311A (en) | S-cyclohexenylalkylhydantoins | |
GB706409A (en) | Process for the preparation of diethylaminoaceto-2m-xylidide | |
GB666578A (en) | Process for the preparation of derivatives of 1, 2, 3 substituted pyrazolones and derivatives obtained by this process | |
GB454423A (en) | Manufacture of anthraquinone compounds containing nitrogen | |
GB414768A (en) | Process for the manufacture of stable diazonium compounds | |
GB595177A (en) | Improvements in or relating to the manufacture of substituted sulphonamido compounds | |
GB669016A (en) | N-benzhydryl-n-acyl-ureas and process for the manufacture of same |