GB376806A - Improvements in polymethylenediguanidine compounds and their process of manufacture - Google Patents
Improvements in polymethylenediguanidine compounds and their process of manufactureInfo
- Publication number
- GB376806A GB376806A GB1022831A GB1022831A GB376806A GB 376806 A GB376806 A GB 376806A GB 1022831 A GB1022831 A GB 1022831A GB 1022831 A GB1022831 A GB 1022831A GB 376806 A GB376806 A GB 376806A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sodium carbonate
- methylene groups
- pancreas preparation
- polymethylenediguanidine
- pancreas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The phosphates, tartrates, and citrates of polymethylenediguanidines containing at least six methylene groups are prepared by treating the carbonates or hydrates of the diguanidines with the respective acid. The products possess therapeutic properties. The carbonates and hydrates are obtained by melting a polymethylenediamine containing at least six methylene groups with guanidine sulphocyanate at about 130-160 DEG C. and precipitating with an alkali hydrate or carbonate in an inert liquid. According to the examples, decamethylenediamine is melted with guanidine sulphocyanate, the product dissolved in alcohol and precipitated with sodium carbonate or dissolved in water and precipitated with caustic potash, and dried; the resulting decamethylenediguanidine is then heated with tartaric or phosphoric acid to give the ditartrate or diphosphate. It is stated that the polymethylenediguanidine diphosphates may be mixed with a pancreas preparation the ferments for which are partially decomposed; the pancreas preparation is neutralized with sodium carbonate and allowed to stand.ALSO:The diphosphates of polymethylenediguanidines containing at least six methylene groups, e.g. decamethylenediguanidine, may be mixed with a pancreas preparation the ferments of which are partially decomposed. The pancreas preparation is neutralized with sodium carbonate and allowed to stand.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1022831A GB376806A (en) | 1931-04-07 | 1931-04-07 | Improvements in polymethylenediguanidine compounds and their process of manufacture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1022831A GB376806A (en) | 1931-04-07 | 1931-04-07 | Improvements in polymethylenediguanidine compounds and their process of manufacture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB376806A true GB376806A (en) | 1932-07-07 |
Family
ID=9963972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1022831A Expired GB376806A (en) | 1931-04-07 | 1931-04-07 | Improvements in polymethylenediguanidine compounds and their process of manufacture |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB376806A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0024780A1 (en) * | 1979-07-09 | 1981-03-11 | Seth Thomas Shaw, Jr. | Medicated intrauterine devices |
| EP0024781A1 (en) * | 1979-07-09 | 1981-03-11 | Seth Thomas Shaw, Jr. | Medicated intrauterine devices |
| EP0024779A1 (en) * | 1979-07-09 | 1981-03-11 | Seth Thomas Shaw, Jr. | Drugs for use with intrauterine devices and intrauterine devices containing said drugs |
| US4381001A (en) | 1979-07-09 | 1983-04-26 | Shaw Jr Seth T | IUD Arrangement |
-
1931
- 1931-04-07 GB GB1022831A patent/GB376806A/en not_active Expired
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4495934A (en) * | 1978-07-25 | 1985-01-29 | Shaw Jr Seth T | IUD Arrangement |
| EP0024780A1 (en) * | 1979-07-09 | 1981-03-11 | Seth Thomas Shaw, Jr. | Medicated intrauterine devices |
| EP0024781A1 (en) * | 1979-07-09 | 1981-03-11 | Seth Thomas Shaw, Jr. | Medicated intrauterine devices |
| EP0024779A1 (en) * | 1979-07-09 | 1981-03-11 | Seth Thomas Shaw, Jr. | Drugs for use with intrauterine devices and intrauterine devices containing said drugs |
| US4381001A (en) | 1979-07-09 | 1983-04-26 | Shaw Jr Seth T | IUD Arrangement |
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