GB361437A - Improvements relating to the manufacture of x-ray photographs of the urogenital system - Google Patents
Improvements relating to the manufacture of x-ray photographs of the urogenital systemInfo
- Publication number
- GB361437A GB361437A GB25474/30A GB2547430A GB361437A GB 361437 A GB361437 A GB 361437A GB 25474/30 A GB25474/30 A GB 25474/30A GB 2547430 A GB2547430 A GB 2547430A GB 361437 A GB361437 A GB 361437A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sodium
- iodhydrin
- dibrom
- glucose
- boiling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
Abstract
6-Glucose-iodhydrin is prepared by saponifying tetra - acetyl - 6 - glucose - iodhydrin. Sodium 3.5-dibrom - 4 - acetamino - 1 - benzoate is prepared by boiling p-amino-benzoic acid and the calculated quantity of bromine, both in glacial acetic acid for two hours, with stirring, to produce 3-5-dibrom-4-amino-1-benzoic acid, boiling with acetic anhydride to produce the acetyl compound, and adding the calculated quantity of sodium ethylate in alcoholic solution.ALSO:In the production of X-ray photographs of the urogenital system of an organism an X-ray contrast medium is employed comprising an aqueous solution of an easily soluble organic bromine or iodine compound substantially indifferent to the organism. The medium is administered internally, preferably by intravenous injection, the quantities employed for the human organism comprising 10-100 cc., preferably 60 cc., of water containing at least 2, and preferably 18-20 gms., of iodine in combined form; larger proportions of bromine must be employed. Suitable compounds are sodium 2-oxo-5-iodo-pyridine-N-acetate; di-iodo-chelidamic acid sodium and ammonium salts; aliphatic halogen carboxylic acids such as b -iodo-propionic acid; halogen alkyl sulphonic acids; halogen alkyl sulphuric acids; halogen substituted polyhydroxy compounds such as 6-glucose-iodhydrin, prepared by saponifying tetra-acetyl-6-glucose-iodhydrin; sodium 3,5-dibrom-4-acetamino-1-benzoate, prepared by boiling p-amino-benzoic acid and the calculated quantity of bromine, both in glacial acetic acid for two hours, with stirring, to produce 3-5-dibrom-4-amino-1-benzoic acid, boiling with acetic anhydride to produce the acetyl compound, and adding the calculated quantity of sodium ethylate in alcoholic solution. The Specification as open to inspection under Sect. 91 (3) (a) refers to the use of organic halogen compounds in general. This subject-matter appears in the Specification as accepted only in the restricted form set out above.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2269489X | 1929-09-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB361437A true GB361437A (en) | 1931-11-26 |
Family
ID=7993153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB25474/30A Expired GB361437A (en) | 1929-09-25 | 1930-08-26 | Improvements relating to the manufacture of x-ray photographs of the urogenital system |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US2269489A (en) |
| AT (1) | AT129942B (en) |
| CH (1) | CH150122A (en) |
| ES (1) | ES119679A1 (en) |
| FR (1) | FR709790A (en) |
| GB (1) | GB361437A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0073715A1 (en) * | 1981-08-28 | 1983-03-09 | Société dite: GUERBET S.A. | Brominated compounds for use in opacifying products |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6147386A (en) * | 1984-07-31 | 1986-03-07 | 東洋製罐株式会社 | Cap cover closing head device |
-
1930
- 1930-08-13 CH CH150122D patent/CH150122A/en unknown
- 1930-08-13 AT AT129942D patent/AT129942B/en active
- 1930-08-22 FR FR709790D patent/FR709790A/en not_active Expired
- 1930-08-26 GB GB25474/30A patent/GB361437A/en not_active Expired
- 1930-09-03 ES ES0119679A patent/ES119679A1/en not_active Expired
-
1938
- 1938-10-11 US US234403A patent/US2269489A/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0073715A1 (en) * | 1981-08-28 | 1983-03-09 | Société dite: GUERBET S.A. | Brominated compounds for use in opacifying products |
Also Published As
| Publication number | Publication date |
|---|---|
| FR709790A (en) | 1931-08-13 |
| ES119679A1 (en) | 1930-10-16 |
| CH150122A (en) | 1930-10-15 |
| US2269489A (en) | 1942-01-13 |
| AT129942B (en) | 1932-10-10 |
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