GB313924A - Process for the preparation of a pure hormone from the anterior lobe of the hypophysis - Google Patents
Process for the preparation of a pure hormone from the anterior lobe of the hypophysisInfo
- Publication number
- GB313924A GB313924A GB18722/29A GB1872229A GB313924A GB 313924 A GB313924 A GB 313924A GB 18722/29 A GB18722/29 A GB 18722/29A GB 1872229 A GB1872229 A GB 1872229A GB 313924 A GB313924 A GB 313924A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hormone
- treated
- precipitate
- hypophysis
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
313,924. Schering-Kahlbaum Akt.- Ges. June 19, 1928, [Convention date]. Medicines for internal use.-The hormone of the anterior lobe of the hypophysis, which is found also in the blood, urine, fµces, male and female sexual glands, and placenta, is prepared by treating an aqueous preparation of these organs or liquids with compounds of the alkaline earths or of the heavy metals to precipitate salts and ballast materials, and then separating the hormone in the usual manner by adding an organic solvent to the residual aqueous solution. According to an example urine is concentrated, acidified with acetic acid, filtered, treated by addition of concentrated barium chloride solution, to precipitate impurities, and the filtrate treated with sodium sulphate to remove excess of barium, again filtered, and treated with three times its volume of methyl alcohol to precipitate the hormone. The hormone may be further purified by repeated solution in water and precipitation with alcohol. In further examples-(1) concentrated urine is treated with lead acetate, excess of which is removed by means of sulphuretted hydrogen; (2) finely divided placenta suspended in water is treated with calcium hydroxide and then with carbon dioxide to precipitate calcium carbonate; and (3) anterior lobes of hypophysis are finely divided in a colloid mill and suspended in acidified water, the mass filtered, and the filtrate treated with barium chloride solution. In each of these further examples the hormone is finally separated from the solution in the same manneras in the first example.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE313924X | 1928-06-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB313924A true GB313924A (en) | 1930-09-18 |
Family
ID=6143252
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB18722/29A Expired GB313924A (en) | 1928-06-19 | 1929-06-18 | Process for the preparation of a pure hormone from the anterior lobe of the hypophysis |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB313924A (en) |
-
1929
- 1929-06-18 GB GB18722/29A patent/GB313924A/en not_active Expired
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB548197A (en) | Producing high quality magnesium compounds from magnesium-containing substances | |
US1995709A (en) | Hydroxyphenylpropanolamine hydrochloride | |
GB413714A (en) | Improvements in the manufacture and production of pure lecithin | |
GB313924A (en) | Process for the preparation of a pure hormone from the anterior lobe of the hypophysis | |
US2580195A (en) | Method of purifying 4-aminosalicylic acid | |
GB173479A (en) | Improved process of purifying lactic acid | |
US2219167A (en) | Process for the manufacture of preparations containing the circulatory hormone callicrein | |
GB532301A (en) | Improvements in and relating to the preparation of sodium bicarbonate and mixtures containing sodium bicarbonate | |
US2571679A (en) | Process for preparing purified heparin | |
US1977525A (en) | Manufacture of adenosine phosphoric acid | |
AT153216B (en) | Process for the preparation of complex gold keratin compounds. | |
SU67225A1 (en) | Method of cleaning technical uric acid | |
DE667220C (en) | Process for the production of preparations containing the circulatory hormone kallikrein | |
SU23563A1 (en) | Method for producing hormones of the anterior pituitary gland | |
SU416316A1 (en) | ||
US1890373A (en) | Hormone and the process of obtaining same | |
GB496946A (en) | Process for the manufacture of preparations containing the circulatory hormone callicrein | |
DE733809C (en) | Process for the extraction of glycosides from Strophanthus Kombe | |
GB511186A (en) | Method of producing purified toxiferine, the active principle of calabash-curare | |
GB288132A (en) | Process for the manufacture of a therapeutically active substance from the anterior lobes of the pituitary body | |
GB497081A (en) | Improvements in obtaining the antineuritic vitamin | |
GB513304A (en) | Process for the manufacture of therapeutically valuable gold compounds | |
GB500489A (en) | Improvements in or relating to the manufacture of water-soluble hyposulphites | |
GB503642A (en) | Improvements relating to the concentration and purification of gonadotropic hormones | |
CH268690A (en) | Process for the preparation of adermin (vitamin B6). |