GB2635971A - Dental/medical device including polydioxanone, use of such device for guided tissue reconstruction and/or regeneration and production process of such device - Google Patents

Dental/medical device including polydioxanone, use of such device for guided tissue reconstruction and/or regeneration and production process of such device Download PDF

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Publication number
GB2635971A
GB2635971A GB2417460.9A GB202417460A GB2635971A GB 2635971 A GB2635971 A GB 2635971A GB 202417460 A GB202417460 A GB 202417460A GB 2635971 A GB2635971 A GB 2635971A
Authority
GB
United Kingdom
Prior art keywords
varying
regeneration
dental
stem cells
tissue reconstruction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB2417460.9A
Other languages
English (en)
Other versions
GB202417460D0 (en
Inventor
Blay Alberto
Santos De Souza Silva Edvaldo
Yoshiko Matsubara Elaine
Awad Shibli Jamil
Pilatti Mendes Da Silva Livia
Saska Specian Sybele
Tunchel Samy
Cohen Moises
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
M3 Health Ind E Comercio De Produtos Medicos Odontologicos E Correlatos S A
M3 Health Industria e Comercio de Produtos Medicos Odontologicos e Correlatos SA
Original Assignee
M3 Health Ind E Comercio De Produtos Medicos Odontologicos E Correlatos S A
M3 Health Industria e Comercio de Produtos Medicos Odontologicos e Correlatos SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by M3 Health Ind E Comercio De Produtos Medicos Odontologicos E Correlatos S A, M3 Health Industria e Comercio de Produtos Medicos Odontologicos e Correlatos SA filed Critical M3 Health Ind E Comercio De Produtos Medicos Odontologicos E Correlatos S A
Publication of GB202417460D0 publication Critical patent/GB202417460D0/en
Publication of GB2635971A publication Critical patent/GB2635971A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0003—Not used, see subgroups
    • A61C8/0004—Consolidating natural teeth
    • A61C8/0006—Periodontal tissue or bone regeneration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • A61F2/105—Skin implants, e.g. artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/142—Cornea, e.g. artificial corneae, keratoprostheses or corneal implants for repair of defective corneal tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B32/00—Carbon; Compounds thereof
    • C01B32/15—Nano-sized carbon materials
    • C01B32/182—Graphene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dentistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Composite Materials (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nanotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
GB2417460.9A 2022-06-06 2023-06-06 Dental/medical device including polydioxanone, use of such device for guided tissue reconstruction and/or regeneration and production process of such device Pending GB2635971A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263349344P 2022-06-06 2022-06-06
PCT/BR2023/050185 WO2023235949A1 (en) 2022-06-06 2023-06-06 Dental/medical device including polydioxanone, use of such device for guided tissue reconstruction and/or regeneration and production process of such device

Publications (2)

Publication Number Publication Date
GB202417460D0 GB202417460D0 (en) 2025-01-15
GB2635971A true GB2635971A (en) 2025-06-04

Family

ID=89117262

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2417460.9A Pending GB2635971A (en) 2022-06-06 2023-06-06 Dental/medical device including polydioxanone, use of such device for guided tissue reconstruction and/or regeneration and production process of such device

Country Status (10)

Country Link
US (1) US20260000490A1 (enExample)
EP (1) EP4536305A1 (enExample)
JP (1) JP2025519387A (enExample)
KR (1) KR20250020505A (enExample)
CN (1) CN119300872A (enExample)
AU (1) AU2023282946A1 (enExample)
CA (1) CA3257464A1 (enExample)
GB (1) GB2635971A (enExample)
MX (1) MX2024014917A (enExample)
WO (1) WO2023235949A1 (enExample)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170021060A1 (en) * 2015-07-24 2017-01-26 The Texas A&M University System Shape memory polymer scaffolds for tissue defects
US20180326123A1 (en) * 2017-05-10 2018-11-15 Board Of Trustees Of The University Of Arkansas Biocompatible structure for tissue regeneration and methods of making and using same
US20200155724A1 (en) * 2013-10-04 2020-05-21 Oxford University Innovation Limited Scaffold
US20210244854A1 (en) * 2020-02-06 2021-08-12 Board Of Trustees Of The University Of Arkansas Expandable bone and tissue regeneration system, and applications of same
WO2022081697A1 (en) * 2020-10-14 2022-04-21 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Hybrid micro molding-fiber deposition substrate processing for cell biology manipulation and local anisotropy

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200155724A1 (en) * 2013-10-04 2020-05-21 Oxford University Innovation Limited Scaffold
US20170021060A1 (en) * 2015-07-24 2017-01-26 The Texas A&M University System Shape memory polymer scaffolds for tissue defects
US20180326123A1 (en) * 2017-05-10 2018-11-15 Board Of Trustees Of The University Of Arkansas Biocompatible structure for tissue regeneration and methods of making and using same
US20210244854A1 (en) * 2020-02-06 2021-08-12 Board Of Trustees Of The University Of Arkansas Expandable bone and tissue regeneration system, and applications of same
WO2022081697A1 (en) * 2020-10-14 2022-04-21 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Hybrid micro molding-fiber deposition substrate processing for cell biology manipulation and local anisotropy

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Bressan E; Ferroni L; Gardin C et al; Graphene based scaffolds effects on stem cells commitment Journal of Translational Medicine 12, 296 (2014) http://dx.doi.org/10.1186/s12967-014-0296-9 All document *
Saska S; Pilatti L; Silva E S d S; Nagasawa M A; Câmara D; Lizier N; Finger E; Dyszkiewicz Konwiska M; Kempisty B; Tunchel S et al., Polydioxanone-Based Membranes for Bone Regeneration POLYMERS, 2021, 13, 1685 http://dx.doi.org/10.3390/polym13111685 All document *
Scaffaro R; Maio A; Lopresti F; Botta L.Nanocarbons in Electrospun Polymeric Nanomats for Tissue Engineering: A Review, Polymers 2017, 9, 76, http://dx.doi.org/10.3390/polym9020076 All document *
Shah S; Et Al Guiding Stem Cell Differentiation into Oligodendrocytes Using Graphene-Nanofiber Hybrid Scaffolds Adv Mater, 26: 3673-3680 http://dx.doi.org/10.1002/adma.201400523 All document *
Xu YiboChen ChuanxinHellwarth Peter BBao Xiaoping Biomaterials for stem cell engineering and biomanufacturing Bioactive Materials, Volume 4, 2019, Page(s):366 - 379 http://dx.doi.org/10.1016/j.bioactmat.2019.11.002 All document *
Yu Luo; He Shen; Yongxiang Fang; Yuhua Cao; Jie Huang; Mengxin Zhang; Jianwu Dai; Xiangyang Shi; Zhijun Zhang Enhanced Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells on Graphene Oxide-Incorporated Electrospun Poly(lactic- co -glycolic acid) Nanofibrous Mats Applied Materials *

Also Published As

Publication number Publication date
CN119300872A (zh) 2025-01-10
JP2025519387A (ja) 2025-06-26
MX2024014917A (es) 2025-01-09
AU2023282946A1 (en) 2024-12-19
WO2023235949A1 (en) 2023-12-14
CA3257464A1 (en) 2023-12-14
KR20250020505A (ko) 2025-02-11
EP4536305A1 (en) 2025-04-16
US20260000490A1 (en) 2026-01-01
GB202417460D0 (en) 2025-01-15

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