GB2573932B - Automated machine for sorting of biological fluids - Google Patents

Automated machine for sorting of biological fluids Download PDF

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Publication number
GB2573932B
GB2573932B GB1911665.6A GB201911665A GB2573932B GB 2573932 B GB2573932 B GB 2573932B GB 201911665 A GB201911665 A GB 201911665A GB 2573932 B GB2573932 B GB 2573932B
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GB
United Kingdom
Prior art keywords
sorting
biological fluids
automated machine
automated
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1911665.6A
Other languages
English (en)
Other versions
GB2573932A (en
GB201911665D0 (en
Inventor
Hardy Wunsch Benjamin
Thomas Smith Joshua
Hu Huan
Albert Pereira Michael
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
International Business Machines Corp
Original Assignee
International Business Machines Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by International Business Machines Corp filed Critical International Business Machines Corp
Publication of GB201911665D0 publication Critical patent/GB201911665D0/en
Publication of GB2573932A publication Critical patent/GB2573932A/en
Application granted granted Critical
Publication of GB2573932B publication Critical patent/GB2573932B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/028Modular arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/14Means for pressure control
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/52Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Engineering & Computer Science (AREA)
  • Quality & Reliability (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
GB1911665.6A 2017-02-16 2018-01-24 Automated machine for sorting of biological fluids Active GB2573932B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/434,985 US10471425B2 (en) 2017-02-16 2017-02-16 Automated machine for sorting of biological fluids
PCT/IB2018/050422 WO2018150281A1 (en) 2017-02-16 2018-01-24 Automated machine for sorting of biological fluids

Publications (3)

Publication Number Publication Date
GB201911665D0 GB201911665D0 (en) 2019-10-02
GB2573932A GB2573932A (en) 2019-11-20
GB2573932B true GB2573932B (en) 2022-06-15

Family

ID=63104547

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1911665.6A Active GB2573932B (en) 2017-02-16 2018-01-24 Automated machine for sorting of biological fluids

Country Status (6)

Country Link
US (2) US10471425B2 (ja)
JP (1) JP7011191B2 (ja)
CN (1) CN110248735B (ja)
DE (1) DE112018000184B4 (ja)
GB (1) GB2573932B (ja)
WO (1) WO2018150281A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10471425B2 (en) 2017-02-16 2019-11-12 International Business Machines Corporation Automated machine for sorting of biological fluids
US10820852B2 (en) * 2018-12-18 2020-11-03 International Business Machines Corporation Allergic early detection wearable device
JP2022543774A (ja) * 2019-08-06 2022-10-14 スナップドラゴン ケミストリー,インコーポレイテッド 連続流光反応器
US11517873B2 (en) * 2019-10-29 2022-12-06 International Business Machines Corporation Controlled chemical synthesis using polymer substrates and nanofluidic separation systems
EP4245414A1 (en) * 2022-03-16 2023-09-20 Overture Life, Inc Biochip coupling systems and devices
WO2023119194A1 (en) * 2021-12-22 2023-06-29 Overture Life, Inc. Biochip coupling system device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060269446A1 (en) * 2004-12-03 2006-11-30 Cytonome, Inc. Unitary cartridge for particle processing
US20070090026A1 (en) * 2005-10-06 2007-04-26 Jongyoon Han Continuous biomolecule separation in a nanofilter
EP2124036A1 (en) * 2008-05-20 2009-11-25 Agilent Technologies, Inc. Pre-positioning and guiding mechanism for inserting a flow cell in a detector
US20120214167A1 (en) * 2009-07-29 2012-08-23 Iti Scotland Limited Apparatus for bio-automation
CN104136596A (zh) * 2011-10-21 2014-11-05 尹特根埃克斯有限公司 样品制备、处理和分析系统

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6114122A (en) * 1996-03-26 2000-09-05 Affymetrix, Inc. Fluidics station with a mounting system and method of using
US20020159919A1 (en) * 1998-01-09 2002-10-31 Carl Churchill Method and apparatus for high-speed microfluidic dispensing using text file control
US7000330B2 (en) 2002-08-21 2006-02-21 Honeywell International Inc. Method and apparatus for receiving a removable media member
AU2003216175A1 (en) * 2002-02-04 2003-09-02 Colorado School Of Mines Laminar flow-based separations of colloidal and cellular particles
US6808075B2 (en) 2002-04-17 2004-10-26 Cytonome, Inc. Method and apparatus for sorting particles
WO2004029221A2 (en) 2002-09-27 2004-04-08 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
US20060223178A1 (en) 2005-04-05 2006-10-05 Tom Barber Devices and methods for magnetic enrichment of cells and other particles
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
JP2009511001A (ja) 2005-09-15 2009-03-19 アルテミス ヘルス,インク. 細胞及びその他の粒子を磁気濃縮するためのデバイス並びに方法
CN103499466B (zh) * 2006-01-18 2017-04-12 阿戈斯治疗公司 用于处理封闭容器中的样品的系统和方法以及相关装置
EP2040843B1 (en) 2006-06-01 2020-02-26 The Trustees of Princeton University Apparatus for continuous particle separation
CN100567734C (zh) * 2008-03-26 2009-12-09 深圳先进技术研究院 一种多通道微型泵装置及其驱动方法
FR2931141B1 (fr) 2008-05-13 2011-07-01 Commissariat Energie Atomique Systeme microfluidique et procede pour le tri d'amas de cellules et de preference pour leur encapsulation en continu suite a leur tri
EP2304414B1 (en) 2008-07-24 2017-03-15 The Trustees of Princeton University Bump array device having asymmetric gaps for segregation of particles
CN103727021B (zh) * 2008-10-22 2018-01-23 生物技术公司 用于检测输注组件中的至少一个功能异常的方法
KR101443133B1 (ko) * 2009-12-23 2014-11-03 사이토베라 인코포레이티드 입자여과를 위한 시스템 및 방법
EP3150690B1 (en) * 2010-02-23 2022-04-06 Luminex Corporation Instrument for the manipulation of cartridges to perform nucleic acid isolation and amplification processes
TWI690594B (zh) * 2011-01-21 2020-04-11 美商賽瑞諾斯Ip有限責任公司 樣本使用最大化之系統及方法
CA2850335A1 (en) 2011-09-30 2013-06-20 The Regents Of The University Of California Devices and methods for shape-based particle separation
CN104114282B (zh) * 2011-09-30 2017-07-04 生命技术公司 用于生物分析的系统和方法
CN103834558A (zh) 2012-11-21 2014-06-04 中国科学院深圳先进技术研究院 血液细胞快速分选装置及其制造方法
EP3608022A1 (en) 2013-03-15 2020-02-12 The Trustees of Princeton University Methods and devices for high throughput purification
CN103755777B (zh) * 2014-01-16 2015-09-23 北京中科纳泰生物科技有限公司 一种气控固相多肽合成微流控芯片装置及其应用
KR20160123305A (ko) 2014-01-20 2016-10-25 핼시언 바이오메디컬, 인코퍼레이티드 전혈의 수동 분리
WO2015191916A1 (en) * 2014-06-11 2015-12-17 Micronics, Inc. Microfluidic cartridges and apparatus with integrated assay controls for analysis of nucleic acids
US10058895B2 (en) 2014-11-26 2018-08-28 International Business Machines Corporation Continuous flow, size-based separation of entities down to the nanometer scale using nanopillar arrays
US9636675B2 (en) 2014-11-26 2017-05-02 International Business Machines Corporation Pillar array structure with uniform and high aspect ratio nanometer gaps
CN107921381B (zh) * 2015-04-28 2021-11-09 不列颠哥伦比亚大学 一次性微流控盒
US10156568B2 (en) 2015-04-30 2018-12-18 International Business Machines Corporation Immunoassay for detection of virus-antibody nanocomplexes in solution by chip-based pillar array
AU2016287499B2 (en) * 2015-06-29 2022-08-04 Caris Science, Inc. Therapeutic oligonucleotides
CN105062866B (zh) * 2015-08-18 2016-04-13 深圳睿思生命科技有限公司 用于外周血循环肿瘤细胞的一次性分离芯片模块及其使用方法
CN105861297A (zh) 2016-03-29 2016-08-17 厦门大学 一种循环肿瘤细胞检测芯片及其应用
US10471425B2 (en) 2017-02-16 2019-11-12 International Business Machines Corporation Automated machine for sorting of biological fluids

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060269446A1 (en) * 2004-12-03 2006-11-30 Cytonome, Inc. Unitary cartridge for particle processing
US20070090026A1 (en) * 2005-10-06 2007-04-26 Jongyoon Han Continuous biomolecule separation in a nanofilter
EP2124036A1 (en) * 2008-05-20 2009-11-25 Agilent Technologies, Inc. Pre-positioning and guiding mechanism for inserting a flow cell in a detector
US20120214167A1 (en) * 2009-07-29 2012-08-23 Iti Scotland Limited Apparatus for bio-automation
CN104136596A (zh) * 2011-10-21 2014-11-05 尹特根埃克斯有限公司 样品制备、处理和分析系统

Also Published As

Publication number Publication date
US20180231576A1 (en) 2018-08-16
DE112018000184T5 (de) 2019-10-02
CN110248735A (zh) 2019-09-17
DE112018000184B4 (de) 2022-10-06
CN110248735B (zh) 2021-11-23
JP2020511120A (ja) 2020-04-16
GB2573932A (en) 2019-11-20
US10471425B2 (en) 2019-11-12
JP7011191B2 (ja) 2022-01-26
GB201911665D0 (en) 2019-10-02
WO2018150281A1 (en) 2018-08-23
US11318464B2 (en) 2022-05-03
US20190388891A1 (en) 2019-12-26

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Effective date: 20220706