GB2563440B - Securing a sensor at the heart - Google Patents

Securing a sensor at the heart Download PDF

Info

Publication number
GB2563440B
GB2563440B GB1709621.5A GB201709621A GB2563440B GB 2563440 B GB2563440 B GB 2563440B GB 201709621 A GB201709621 A GB 201709621A GB 2563440 B GB2563440 B GB 2563440B
Authority
GB
United Kingdom
Prior art keywords
heart
sensor
anchor
lead
main lead
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1709621.5A
Other languages
English (en)
Other versions
GB201709621D0 (en
GB2563440A (en
Inventor
Fosse Erik
Tyssø Jonas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiaccs AS
Original Assignee
Cardiaccs AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiaccs AS filed Critical Cardiaccs AS
Priority to GB1709621.5A priority Critical patent/GB2563440B/en
Publication of GB201709621D0 publication Critical patent/GB201709621D0/en
Priority to US16/008,830 priority patent/US10384058B2/en
Priority to JP2019569889A priority patent/JP7166296B2/ja
Priority to PCT/IB2018/054432 priority patent/WO2018229726A1/en
Priority to EP18746273.4A priority patent/EP3638358B1/en
Priority to CA3065744A priority patent/CA3065744A1/en
Publication of GB2563440A publication Critical patent/GB2563440A/en
Application granted granted Critical
Publication of GB2563440B publication Critical patent/GB2563440B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0587—Epicardial electrode systems; Endocardial electrodes piercing the pericardium
    • A61N1/059—Anchoring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6879—Means for maintaining contact with the body
    • A61B5/6882—Anchoring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056—Transvascular endocardial electrode systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0587—Epicardial electrode systems; Endocardial electrodes piercing the pericardium
    • A61N1/0595—Temporary leads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
    • A61N1/36578—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by mechanical motion of the heart wall, e.g. measured by an accelerometer or microphone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/37—Monitoring; Protecting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/042—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors plastically deformed during insertion
    • A61B2017/0422—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors plastically deformed during insertion by insertion of a separate member into the body of the anchor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
    • A61B5/1107—Measuring contraction of parts of the body, e.g. organ or muscle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6869—Heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0587—Epicardial electrode systems; Endocardial electrodes piercing the pericardium
    • A61N1/0592—Introducing the lead through the pericardium with a needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
    • A61N1/36542—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by body motion, e.g. acceleration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Physiology (AREA)
  • Vascular Medicine (AREA)
  • Electrotherapy Devices (AREA)
GB1709621.5A 2017-06-16 2017-06-16 Securing a sensor at the heart Active GB2563440B (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GB1709621.5A GB2563440B (en) 2017-06-16 2017-06-16 Securing a sensor at the heart
US16/008,830 US10384058B2 (en) 2017-06-16 2018-06-14 Methods and devices for securing a sensor at the heart
EP18746273.4A EP3638358B1 (en) 2017-06-16 2018-06-15 Devices for securing a sensor at the heart
PCT/IB2018/054432 WO2018229726A1 (en) 2017-06-16 2018-06-15 Methods and devices for securing a sensor at the heart
JP2019569889A JP7166296B2 (ja) 2017-06-16 2018-06-15 心臓にセンサを固定するための方法およびデバイス
CA3065744A CA3065744A1 (en) 2017-06-16 2018-06-15 Methods and devices for securing a sensor at the heart

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1709621.5A GB2563440B (en) 2017-06-16 2017-06-16 Securing a sensor at the heart

Publications (3)

Publication Number Publication Date
GB201709621D0 GB201709621D0 (en) 2017-08-02
GB2563440A GB2563440A (en) 2018-12-19
GB2563440B true GB2563440B (en) 2019-06-05

Family

ID=59462287

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1709621.5A Active GB2563440B (en) 2017-06-16 2017-06-16 Securing a sensor at the heart

Country Status (6)

Country Link
US (1) US10384058B2 (enExample)
EP (1) EP3638358B1 (enExample)
JP (1) JP7166296B2 (enExample)
CA (1) CA3065744A1 (enExample)
GB (1) GB2563440B (enExample)
WO (1) WO2018229726A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2641249A (en) 2024-05-21 2025-11-26 Cardiaccs As Wireless monitoring of cardiac function

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0211166A2 (de) * 1985-06-28 1987-02-25 Peter Dr. Ing. Osypka Defibrillations-Elektrode
US20030105496A1 (en) * 2001-12-05 2003-06-05 Cardiac Pacemakers, Inc. Cardiac resynchronization system employing mechanical measurement of cardiac walls
US20140243593A1 (en) * 2013-02-26 2014-08-28 Endostim, Inc. Implantable Electrical Stimulation Leads
WO2016201082A1 (en) * 2015-06-10 2016-12-15 Cardio Thrive, Inc. Multivector patient electrode system and method of use

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4437475A (en) * 1981-08-28 1984-03-20 Medtronic, Inc. Transvenous cardiovascular integrated lead anchoring sleeve, protector, and permanent lead introducer stop gap
US4414986A (en) * 1982-01-29 1983-11-15 Medtronic, Inc. Biomedical stimulation lead
DE3631155A1 (de) 1986-09-12 1988-03-24 Alt Eckhard Frequenzvariabler herzschrittmacher mit belastungsadaequatem frequenzverhalten
US4967755A (en) * 1989-02-28 1990-11-06 Medtronic, Inc. Electromedical lead with pressure sensor
JPH02277468A (ja) * 1989-04-18 1990-11-14 Nippon Zeon Co Ltd センサ構成素子付きカテーテル
US5324323A (en) * 1992-09-09 1994-06-28 Telectronics Pacing Systems, Inc. Multiple channel cardiosynchronous myoplasty apparatus
US5350419A (en) * 1992-09-18 1994-09-27 Ethicon, Inc. Cardiac pacing lead
US5353800A (en) * 1992-12-11 1994-10-11 Medtronic, Inc. Implantable pressure sensor lead
US5376108A (en) * 1993-05-20 1994-12-27 Telectronics Pacing Systems, Inc. Electrode lead anchoring apparatus and method employing dual suture collars
US5609612A (en) 1993-10-05 1997-03-11 Sorin Biomedica Cardio S.P.A. Device for determining myocardial function and corresponding procedure and method
IT1260692B (it) 1993-10-05 1996-04-22 Sorin Biomedica Spa Dispositivo per la determinazione della funzione miocardica e relativoprocedimento.
US5476500A (en) * 1993-12-20 1995-12-19 Ventritex, Inc. Endocardial lead system with defibrillation electrode fixation
EP0823263A1 (de) * 1996-08-06 1998-02-11 Dr.-Ing. P. Osypka GmbH Verbindungselement für ein äusseres Endstück einer chirurgischen Elektrode
US6221024B1 (en) * 1998-07-20 2001-04-24 Medtronic, Inc. Implantable pressure sensor and method of fabrication
US6434431B1 (en) 2000-01-20 2002-08-13 Medtronic, Inc. Intramuscular medical electrical lead with fixation member
US6658292B2 (en) 2001-08-24 2003-12-02 Pacesetter, Inc. Detection of patient's position and activity status using 3D accelerometer-based position sensor
US6937899B2 (en) * 2001-08-30 2005-08-30 Medtronic, Inc. Ischemia detection
NO20016385L (no) 2001-12-27 2003-06-30 Medinnova Sf System for å overvåke pulsendringer, fortrinnsvis en hjertemuskel
JP4505455B2 (ja) * 2003-04-10 2010-07-21 カーディアック ペースメイカーズ， インコーポレイテッド 心臓電極固定システム
US7203551B2 (en) * 2003-04-25 2007-04-10 Medtronic, Inc. Implantable lead-based sensor powered by piezoelectric transformer
US7142919B2 (en) 2003-10-24 2006-11-28 Medtronic, Inc. Reconfigurable, fault tolerant multiple-electrode cardiac lead systems
EP1618919B1 (de) * 2004-07-20 2012-07-04 Biotronik CRM Patent AG Fixierung für implantierbare Elektroden und Katheter
US7200437B1 (en) 2004-10-13 2007-04-03 Pacesetter, Inc. Tissue contact for satellite cardiac pacemaker
US20060178586A1 (en) 2005-02-07 2006-08-10 Dobak John D Iii Devices and methods for accelerometer-based characterization of cardiac function and identification of LV target pacing zones
US8406901B2 (en) 2006-04-27 2013-03-26 Medtronic, Inc. Sutureless implantable medical device fixation
EP3527255B1 (en) * 2006-10-13 2020-08-05 Cyberonics, Inc. Obstructive sleep apnea treatment devices and systems
US8282568B2 (en) 2007-04-30 2012-10-09 Bio-Medisinsk Innovasjon As Method for estimating cardiac pumping capacity
US20100137949A1 (en) * 2008-05-27 2010-06-03 The Cleveland Clinic Foundation Bifurcated electrical lead and method of use
US20110224655A1 (en) * 2008-09-11 2011-09-15 Asirvatham Samuel J Central core multifunctional cardiac devices
IT1393012B1 (it) 2008-12-16 2012-04-11 Tre Esse Progettazione Biomedica S R L Dispositivo telemetrico impiantabile, per il monitoraggio del cuore.
US8632473B2 (en) 2009-01-30 2014-01-21 Medtronic, Inc. Detecting worsening heart failure based on fluid accumulation with respiratory confirmation
US8644927B2 (en) 2009-04-21 2014-02-04 Incube Labs, Llc Apparatus and method for the detection and treatment of atrial fibrillation
EP2448634A1 (en) 2009-07-01 2012-05-09 Medtronic, Inc. Implantable medical device including mechanical stress sensor
US9872981B2 (en) * 2010-09-28 2018-01-23 Biotrace Medical, Inc. Device and method for positioning an electrode in a body cavity
US20120095521A1 (en) 2010-10-19 2012-04-19 Medtronic, Inc. Detection of heart rhythm using an accelerometer
EP2478935B1 (en) 2011-01-21 2017-08-23 NeuroCardiac Innovations, LLC Implantable cardiac devices with body orientation unit
EP2704794A4 (en) 2011-05-06 2014-11-05 Ndsu Res Foundation SELF-ORGANIZING INTELLIGENT ELECTRODE STIMULATION DISPENSING SYSTEM
EP2679275B1 (de) * 2012-06-28 2014-05-14 Peter Osypka Stiftung Epikardiale Mapping-Elektrode
DE102013001021B4 (de) * 2013-01-22 2015-05-13 Osypka Ag Externer Herzschrittmacher mit einer über einen Steckverbinder angeschlossenen, temporär mit einem Herzen verbindbaren Elektrode
US8744572B1 (en) 2013-01-31 2014-06-03 Medronic, Inc. Systems and methods for leadless pacing and shock therapy
US9211415B2 (en) 2013-03-13 2015-12-15 Cardiac Pacemakers, Inc. Phrenic nerve stimulation detection with posture sensing
JP6640194B2 (ja) 2014-05-09 2020-02-05 バイオトレース メディカル， インコーポレイテッド 体腔内に電極を配置するためのデバイスおよび方法
US9278229B1 (en) 2015-01-23 2016-03-08 Medtronic, Inc. Anti-tachyarrhythmia shock detection
WO2018142186A1 (en) 2017-02-01 2018-08-09 Tre Esse Progettazione Biomedica S.R.L. A cardiac function sensor and corresponding implant device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0211166A2 (de) * 1985-06-28 1987-02-25 Peter Dr. Ing. Osypka Defibrillations-Elektrode
US20030105496A1 (en) * 2001-12-05 2003-06-05 Cardiac Pacemakers, Inc. Cardiac resynchronization system employing mechanical measurement of cardiac walls
US20140243593A1 (en) * 2013-02-26 2014-08-28 Endostim, Inc. Implantable Electrical Stimulation Leads
WO2016201082A1 (en) * 2015-06-10 2016-12-15 Cardio Thrive, Inc. Multivector patient electrode system and method of use

Also Published As

Publication number Publication date
WO2018229726A1 (en) 2018-12-20
CA3065744A1 (en) 2018-12-20
JP2020523168A (ja) 2020-08-06
EP3638358A1 (en) 2020-04-22
EP3638358B1 (en) 2023-03-15
JP7166296B2 (ja) 2022-11-07
US10384058B2 (en) 2019-08-20
GB201709621D0 (en) 2017-08-02
US20180361141A1 (en) 2018-12-20
GB2563440A (en) 2018-12-19

Similar Documents

Publication Publication Date Title
US6980866B2 (en) Apparatus for sensing cardiac contractile function
US5666958A (en) Interface module for electrically connecting medical equipment
CN103180008B (zh) 医疗装置的固定附连机构
US5476499A (en) Medical electrode lead with atrial electrode at the distal and ventricular electrode between the distal and proximal ends
US7953495B2 (en) Lead-implant coupling device
US5174303A (en) Pacer lead with replaceable sensor
EP0646388B1 (en) Electrode device
US20080046062A1 (en) Implantable medical lead with proximal retrieval wire
JP5936409B2 (ja) 電極ユニットおよび組織刺激システム
CN107206243A (zh) 用于治疗心律不齐的系统和方法
EP2877238A1 (en) Extracorporeal unit for inspecting the insulation of an electrical wire of an implanted medical device
GB2563440B (en) Securing a sensor at the heart
EP2470070B1 (en) Electrical metering of active fixation lead coupling
EP1136032A1 (en) A method and a device for measuring physical variables in a living body
JP2020523168A5 (enExample)
US9420962B2 (en) Remote lead implant testing
CN118320307B (zh) 心电设备导线套管、系统和使用方法
KR102144041B1 (ko) 의료용 삽입 장치 및 이를 포함하는 신경감지 시스템
JPH02102672A (ja) 皮下埋め込み電極
JP4711703B2 (ja) 経皮電極プローブ
WO2024157102A1 (en) External lead connector system
CN120154821A (zh) 一种新型无间断旋转起搏器术中测试线
JP2014184052A (ja) 神経刺激装置
EP2424616A2 (en) Implantable device, system, and method for measuring physiologic parameters