GB2451044B - Novel thrombolytic molecules and a process therefore - Google Patents

Novel thrombolytic molecules and a process therefore

Info

Publication number
GB2451044B
GB2451044B GB0820681A GB0820681A GB2451044B GB 2451044 B GB2451044 B GB 2451044B GB 0820681 A GB0820681 A GB 0820681A GB 0820681 A GB0820681 A GB 0820681A GB 2451044 B GB2451044 B GB 2451044B
Authority
GB
United Kingdom
Prior art keywords
novel thrombolytic
molecules
thrombolytic molecules
novel
thrombolytic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB0820681A
Other languages
English (en)
Other versions
GB2451044A (en
GB0820681D0 (en
Inventor
Krishna Murthy Ella
Kandaswamy Sumathy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bharat Biotech International Ltd
Original Assignee
Bharat Biotech International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bharat Biotech International Ltd filed Critical Bharat Biotech International Ltd
Publication of GB0820681D0 publication Critical patent/GB0820681D0/en
Publication of GB2451044A publication Critical patent/GB2451044A/en
Application granted granted Critical
Publication of GB2451044B publication Critical patent/GB2451044B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
GB0820681A 2006-05-12 2008-11-11 Novel thrombolytic molecules and a process therefore Active GB2451044B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN843CH2006 2006-05-12
PCT/IN2007/000191 WO2007132481A2 (en) 2006-05-12 2007-05-11 Novel thrombolytic molecules and a process therefor

Publications (3)

Publication Number Publication Date
GB0820681D0 GB0820681D0 (en) 2008-12-17
GB2451044A GB2451044A (en) 2009-01-14
GB2451044B true GB2451044B (en) 2010-06-16

Family

ID=38694310

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0820681A Active GB2451044B (en) 2006-05-12 2008-11-11 Novel thrombolytic molecules and a process therefore

Country Status (4)

Country Link
US (1) US8968728B2 (enExample)
JP (1) JP2009536821A (enExample)
GB (1) GB2451044B (enExample)
WO (1) WO2007132481A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2228657B1 (en) * 2007-11-26 2014-10-22 Fujimori Kogyo Co., Ltd. Microchip and blood monitoring device
JP5752055B2 (ja) 2010-02-10 2015-07-22 藤森工業株式会社 血小板検査用マイクロチップ及びそれを用いた血小板検査装置
US8906421B2 (en) * 2011-06-21 2014-12-09 Med-Genesis, Llc Methods of dissolving blood clots and the like
US20140348781A1 (en) * 2013-05-22 2014-11-27 Children's Healthcare Of Atlanta, Inc Conjugates of gm-csf and il-9, compositions and methods related thereto

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102417A1 (de) * 2001-06-15 2002-12-27 Jochen Reiss Vektor und dessen verwendung in gentherapeutischen verfahren
EP1623715A1 (en) * 2004-07-13 2006-02-08 Charité - Universitätsmedizin Berlin A composition comprising a pharmacologically active agent coupled to a target cell specific component, and a saponin
WO2006029078A2 (en) * 2004-09-07 2006-03-16 The Regents Of The University Of California Targeting transducible molecules to specific cell types

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423512B1 (en) * 1996-07-26 2002-07-23 Novartis Ag Fusion polypeptides
DE19933492B4 (de) * 1999-07-16 2008-01-10 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Konjugat zur Vermittlung eines zell-, kompartiment- oder membranspezifischen Transports von Wirksubstanzen, Verfahren zu dessen Herstellung und dessen Verwendung
CN1480466A (zh) * 2002-09-03 2004-03-10 �й������ž�����ҽѧ��ѧԺ����ҽ 一类溶栓抗凝双功能融合蛋白及应用
MXPA05012306A (es) * 2003-05-16 2006-04-18 Acorda Therapeutics Inc Proteinas de fusion para el tratamiento del snc.
KR20060036476A (ko) * 2003-08-08 2006-04-28 가부시키가이샤 티슈 타겟팅 쟈판 뇌 이동 활성을 가지는 폴리펩티드 및 그 이용
US7332159B2 (en) * 2004-09-30 2008-02-19 Board Of Regents Of The University Of Nebraska Method and composition for inhibiting reperfusion injury in the brain

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102417A1 (de) * 2001-06-15 2002-12-27 Jochen Reiss Vektor und dessen verwendung in gentherapeutischen verfahren
EP1623715A1 (en) * 2004-07-13 2006-02-08 Charité - Universitätsmedizin Berlin A composition comprising a pharmacologically active agent coupled to a target cell specific component, and a saponin
WO2006029078A2 (en) * 2004-09-07 2006-03-16 The Regents Of The University Of California Targeting transducible molecules to specific cell types

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Biotechnology Letters, Vol 20, 1998, SJ Lee et al, "High level secretion of recombinant staphylokinase into periplasm of Escherichia coli", 113-116 *
J Biological Chemistry, Vol 278, 2003, Q Lian et al, "Engineering of a staphylokinase-based fibinolytic agent with antithrombotic activity and targeting capability toward thrombin-rich fibrin and plasma clots", 26677-26685 *

Also Published As

Publication number Publication date
GB2451044A (en) 2009-01-14
WO2007132481A2 (en) 2007-11-22
US20100015123A1 (en) 2010-01-21
US8968728B2 (en) 2015-03-03
GB0820681D0 (en) 2008-12-17
JP2009536821A (ja) 2009-10-22
WO2007132481A3 (en) 2008-06-26

Similar Documents

Publication Publication Date Title
EP2082818A4 (en) RACK AND MANUFACTURING METHOD THEREFOR
GB0818304D0 (en) A beer-type beverage and its process
ZA200900300B (en) Process for acylating celluse
GB0611210D0 (en) Process
GB0619060D0 (en) Novel process
GB0614823D0 (en) Process
TWI310040B (en) Polymethacrylate and production process thereof
ZA200902899B (en) Product and process
GB0600914D0 (en) Process
GB0607394D0 (en) Process
GB2451044B (en) Novel thrombolytic molecules and a process therefore
PL2094456T3 (pl) Płyta pilśniowa i sposób jej wytwarzania
GB0607395D0 (en) Process
SI1981972T1 (sl) Nov postopek
IL192342A0 (en) Product and process
GB0614485D0 (en) Process
GB0611741D0 (en) Process
GB0604874D0 (en) Process
GB0604233D0 (en) Process
GB0614613D0 (en) Process
GB0625275D0 (en) Novel process
GB0602637D0 (en) Novel process
GB0613676D0 (en) Process
GB0606283D0 (en) Process
GB0613826D0 (en) Process and product