GB2409159A - A preparation for treating mud fever in horses - Google Patents
A preparation for treating mud fever in horses Download PDFInfo
- Publication number
- GB2409159A GB2409159A GB0329016A GB0329016A GB2409159A GB 2409159 A GB2409159 A GB 2409159A GB 0329016 A GB0329016 A GB 0329016A GB 0329016 A GB0329016 A GB 0329016A GB 2409159 A GB2409159 A GB 2409159A
- Authority
- GB
- United Kingdom
- Prior art keywords
- preparation
- preparation according
- horses
- branched chain
- mud fever
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 44
- 206010037660 Pyrexia Diseases 0.000 title claims abstract description 19
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims abstract description 14
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 12
- 150000002148 esters Chemical class 0.000 claims abstract description 12
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims abstract description 10
- 235000019271 petrolatum Nutrition 0.000 claims abstract description 8
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 claims abstract description 7
- 239000001500 (2R)-6-methyl-2-[(1R)-4-methyl-1-cyclohex-3-enyl]hept-5-en-2-ol Substances 0.000 claims abstract description 7
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims abstract description 7
- AJBZENLMTKDAEK-UHFFFAOYSA-N 3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-4,9-diol Chemical compound CC12CCC(O)C(C)(C)C1CCC(C1(C)CC3O)(C)C2CCC1C1C3(C)CCC1C(=C)C AJBZENLMTKDAEK-UHFFFAOYSA-N 0.000 claims abstract description 7
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims abstract description 7
- 235000003880 Calendula Nutrition 0.000 claims abstract description 7
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000004166 Lanolin Substances 0.000 claims abstract description 7
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229960000458 allantoin Drugs 0.000 claims abstract description 7
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 claims abstract description 7
- 229960003260 chlorhexidine Drugs 0.000 claims abstract description 7
- 229940039717 lanolin Drugs 0.000 claims abstract description 7
- 235000019388 lanolin Nutrition 0.000 claims abstract description 7
- 229960005323 phenoxyethanol Drugs 0.000 claims abstract description 7
- 229960003500 triclosan Drugs 0.000 claims abstract description 7
- 239000000203 mixture Substances 0.000 claims abstract description 6
- 229920001296 polysiloxane Polymers 0.000 claims abstract description 6
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims abstract description 5
- 229940101267 panthenol Drugs 0.000 claims abstract description 5
- 235000020957 pantothenol Nutrition 0.000 claims abstract description 5
- 239000011619 pantothenol Substances 0.000 claims abstract description 5
- 239000011787 zinc oxide Substances 0.000 claims abstract description 5
- 241000132025 Calendula Species 0.000 claims description 6
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 1
- 239000011701 zinc Substances 0.000 claims 1
- 229910052725 zinc Inorganic materials 0.000 claims 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 abstract description 2
- 206010053615 Thermal burn Diseases 0.000 abstract description 2
- XJNUECKWDBNFJV-UHFFFAOYSA-N hexadecyl 2-ethylhexanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)C(CC)CCCC XJNUECKWDBNFJV-UHFFFAOYSA-N 0.000 abstract description 2
- 240000001432 Calendula officinalis Species 0.000 abstract 1
- 241000283073 Equus caballus Species 0.000 abstract 1
- 241000187845 Dermatophilus congolensis Species 0.000 description 8
- 206010039509 Scab Diseases 0.000 description 7
- 239000004615 ingredient Substances 0.000 description 4
- 230000004888 barrier function Effects 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 208000035415 Reinfection Diseases 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- LQIAZOCLNBBZQK-UHFFFAOYSA-N 1-(1,2-Diphosphanylethyl)pyrrolidin-2-one Chemical compound PCC(P)N1CCCC1=O LQIAZOCLNBBZQK-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- 230000003659 hair regrowth Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 230000008470 skin growth Effects 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
A composition comprising petroleum jelly, silicone, phenoxy ethanol, chlorhexidine diglucomate, triclosan, lanolin, calendula, allantoin, alpha bisabolol and at least one branched chain ester and which is suitable for treating equine mud fever. Preferably the branched chain ester is crodamol CAP (cetearyl octanoate and isopropyl myristate). The preparation may also contain panthenol, tee tree oil, zinc oxide or monopropylene glycol. The preparation may be used to treat mud fever, cracked heel, rain scald or rain rot.
Description
24091 59
A PREPARATION FOR
TREATING MUD FEVER IN HORSES
This invention relates to a preparation for treating Mud Fever in horses.
Mud Fever is an ailment that affects the legs of horses. The ailment is caused by the bacterium dermatophilus congolensis which lies in wet and muddy soil. When the legs of the horses become wet and muddy, the skin on the legs of the horses becomes soft. The soft skin is highly susceptible to infection from the dermatophilus congolensis. The Mud Fever is at its most potent in winter when rain and mud are usually in abundance. The Mud Fever is however an all year ailment and one which causes horses considerable problems. In addition to the skin on the horses' legs becoming soft in muddy and wet conditions, continual wetting and drying of the skin on the horses' legs often causes the skin to chap, which in turn facilitates entry of the dermatophilus congolensis into the horses' skin. Scratches and grazes also facilitate the entry of the dermatophilus congolensis.
It is an aim of the present invention to provide a preparation for treating Mud Fever in horses.
Accordingly, in one non-limiting embodiment of the present invention there is provided a preparation for treating Mud Fever in horses, which preparation comprises: (i) petroleum jelly; (ii) silicone; (iii) phenoxy ethanol; (iv) chlorhexidine diglucomate; (v) triclosan; (vi) lanolin; (vii) calendula; (viii) allantoin; (ix) alpha bisabolol; and (x) at least one branched chain ester able to seal an area being treated for the Mud Fever whilst allowing skin on the area to breath.
The preparation of the present invention is such that the petroleum jelly and the silicon act as a barrier to help repel water from the skin of the horses' legs. The phenoxy ethanol, the chlorhexidine diglucomate and the triclosan act as germicidal ingredients for helping to kill the dermatophilus congolensis. The lanolin, calendula and the petroleum jelly act to soothe the infected area. The allantoin and alpha bisabolol act to heal the infected skin. The branched chain ester or esters act to enable the skin on the horses' legs to breath and this helps facilitate healing. The preparation provides a technically complex and advanced formulation for facilitating the removal of crusts and scabs associated with Mud Fever, the killing of the dermatophilus congolensis, and the provision of a sanitised and waterproof barrier for helping to protect against reinfection. The affected area is resealed after application of the preparation, thereby helping to protect the affected area from wet any muddy conditions.
Preferably, the preparation comprises: (i) 65 - 75% petroleum jelly; (ii) 0. 1-1 0% silicone; (iii) 1% phenoxy ethanol; (iv) 0.1 -1 % chlorhexidine diglucomate; (v) 0.1 - 1% triclosan; (vi) 3 - 7% lanolin; (vii) 2% calendula; (viii) 0.1-1% allantoin; (ix) 0.1-1% alpha bisabolol; and (x) 2% of the said at least one branched ester.
As used herein, all percentages are by weight.
A variety of branched chain esters may be employed, either singly or combined. With a mixture of branched chain esters, then a preferred product is crodamol CAP, which is a blend of cetearyl octanoate and isopropyl myristate.
The preparation may include panthenol. Preferably, there is 0.1 -1% of the panthenol in the preparation.
The preparation may include tee tree oil. Preferably, there is 0.1 1% of the tee tree oil in the preparation.
The preparation may include zinc oxide. Preferably, there is 5-12% of the zinc oxide.
The preparation may include monopropylene glycol. Preferably, there is 3 10% of the monopropylene glycol.
The preparation is preferably in the form of a cream. The preparation may however be in the form of a paste, salve, liquid or any other suitable form for external application.
Reference will now be made to the following Examples.
EXAMPLE I
A preparation was formulated comprising the following ingredients: (i) 65-75% petroleum jelly; (ii) 0.1-10% silicone; (iii) 1% phenoxy ethanol; (iv) 0.1 -1% chlorhexidine diglucomate; (v) 0.1 - 1% triclosan; (vi) 3 7% lanolin; (vii) 2% calendula; (viii) 0.1 -1% allantoin; (ix) 0.1 -1% alpha bisabolol; and (x) 2% crodamol CAP.
The above preparation was formulated by mixing the ingredients together at room temperature. s
Some horses in a field were diagnosed with Mud Fever. They were so diagnosed by virtue of the fact that the legs of the horses had matted hair, crusty exudates, and scabs that had formed on the legs of the horses.
It was noted that horses with white or hairless pasterns with pink skin tendered to suffer more than those horses with hairy legs.
The infected legs of the horses were treated with the preparation.
The preparation firstly assisted in the removal of the crusts and scabs so that the dermatophilus congolensis bacterium was able to be eliminated.
The preparation offered a sanitised and waterproof barrier that was able to protect against re-infection. The affected area was able to be sealed against the further ingress of dermatophilus congolensis due to the horses being permanently in wet and muddy conditions.
It was found that one application of the preparation was able to have a sealing effect on infected areas for up to one week. This sealing promoted skin and hair regrowth.
The Mud Fever crusts and scabs were able to be removed easily and in a faster time than required by many known preparations for treating Mud Fever.
It was found that a re-application of the preparation once per week was effective to prevent the reoccurrence of the Mud Fever.
EXAMPLE 11
Another group of horses were treated with the preparation of Example 1. It was found that in addition to successfully treating the Mud Fever, the preparation was also effective in treating cracked heals, rain scald and rain rot that are found in the horses.
It is to be appreciated that the Examples given above are for illustrative purposes and that modifications may be effected. Thus percentages other than those shown may be employed. In addition, the preparation may include other ingredients such for example as panthenol, tee tree oil, zinc oxide and monopropylene glycol.
Claims (12)
1. A preparation for treating Mud Fever in horses, which preparation comp. nses: (i) petroleum jelly; (ii) silicone; (iii) phenoxy ethanol; (iv) chlorhexidine diglucomate; (v) triclosan; (vi) lanolin; (vii) calendula; (viii) allantoin; (ix) alpha bisabolol; and (x) at least one branched chain ester able to seal an area being treated for the Mud Fever whilst allowing skin on the area to breath.
2. A preparation according to claim 1 and which comprises: (i) 65-75% petroleum jelly; (ii) 0.1 - 10% silicone; (iii) 1% phenoxy ethanol; (iv) 0.1 -1% chlorhexidine diglucomate; (v) 0.1 - 1% triclosan; (vi) 3 - 7% lanolin; (vii) 2% calendula; (viii) 0.1 -1% allantoin; (ix) 0.1-1% alpha bisabolol; and (x) 2% of the said at least one branched chain ester.
3. A preparation according to claim 1 or claim 2 in which there is a mixture of the branched chain esters.
4. A preparation according to claim 3 in which the mixture of the branched chain esters is in the form of crodamol CAP.
5. A preparation according to any one of the preceding claims and including panthanol.
6. A preparation according to claim 5 in which there is 0.1 -1% of the panthenol.
7. A preparation according to any one of the preceding claims and including tee tree oil.
8. A preparation according to claim 7 in which there is 0.1 - 1% of the tee tree oil.
9. A preparation according to any one of the preceding claims and including zinc oxide.
10. A preparation according to claim 9 in which there is 5 -12% of the .
zinc oxlue.
11. A preparation according to any one of the preceding claims and including monopropylene glycol.
12. A preparation according to claim 11 in which there is 3 - 10% of the monopropylene glycol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0329016A GB2409159B (en) | 2003-12-15 | 2003-12-15 | A preparation for use in the treatment of mud fever in horses |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0329016A GB2409159B (en) | 2003-12-15 | 2003-12-15 | A preparation for use in the treatment of mud fever in horses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB0329016D0 GB0329016D0 (en) | 2004-01-14 |
| GB2409159A true GB2409159A (en) | 2005-06-22 |
| GB2409159B GB2409159B (en) | 2008-02-20 |
Family
ID=30130247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0329016A Expired - Lifetime GB2409159B (en) | 2003-12-15 | 2003-12-15 | A preparation for use in the treatment of mud fever in horses |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2409159B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2422765A (en) * | 2005-02-07 | 2006-08-09 | Donald Henry Yates | Pre-grooming preparation |
| EP1787637A2 (en) * | 2005-08-18 | 2007-05-23 | Francisco Caballero Gobern | Composition for veterinary use |
| NL2001955C (en) * | 2008-09-05 | 2010-03-15 | Eden Horse B V | Compositions for treating mud fever. |
| EP3000475A4 (en) * | 2013-05-23 | 2017-01-11 | Kledos Cell Tech, S.L. | Pharmaceutical or cosmetic composition for the regeneration and cicatrisation of the skin |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0103910A1 (en) * | 1982-06-30 | 1984-03-28 | THE PROCTER & GAMBLE COMPANY | Emollient-containing skin conditioning compositions |
| US4604283A (en) * | 1984-04-24 | 1986-08-05 | Gresham Anne L | Hoof conditioner and dressing and methods of use |
| GB2225942A (en) * | 1988-12-13 | 1990-06-20 | May Edwina Julianne Le | Topical veterinary treatment containing calcium soap |
| US5232691A (en) * | 1989-04-26 | 1993-08-03 | Lemole Gerald M | Protective gel composition |
| JP2000063254A (en) * | 1998-08-19 | 2000-02-29 | Kanpehapio:Kk | Skin-protecting cream |
| WO2002036130A1 (en) * | 2000-11-03 | 2002-05-10 | H-10 Limited | Veterinary composition for the topical treatment of traumatized or inflamed skin |
| WO2003043594A2 (en) * | 2001-11-19 | 2003-05-30 | Henkel Kommanditgesellschaft Auf Aktien | Skin protective product |
| GB2401044A (en) * | 2003-05-02 | 2004-11-03 | Julie Elizabeth Almond | Composition for treatment of skin conditions, such as sweet itch in horses, comprising an alcohol, an oil and a derivative of benzene |
-
2003
- 2003-12-15 GB GB0329016A patent/GB2409159B/en not_active Expired - Lifetime
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0103910A1 (en) * | 1982-06-30 | 1984-03-28 | THE PROCTER & GAMBLE COMPANY | Emollient-containing skin conditioning compositions |
| US4604283A (en) * | 1984-04-24 | 1986-08-05 | Gresham Anne L | Hoof conditioner and dressing and methods of use |
| GB2225942A (en) * | 1988-12-13 | 1990-06-20 | May Edwina Julianne Le | Topical veterinary treatment containing calcium soap |
| US5232691A (en) * | 1989-04-26 | 1993-08-03 | Lemole Gerald M | Protective gel composition |
| JP2000063254A (en) * | 1998-08-19 | 2000-02-29 | Kanpehapio:Kk | Skin-protecting cream |
| WO2002036130A1 (en) * | 2000-11-03 | 2002-05-10 | H-10 Limited | Veterinary composition for the topical treatment of traumatized or inflamed skin |
| WO2003043594A2 (en) * | 2001-11-19 | 2003-05-30 | Henkel Kommanditgesellschaft Auf Aktien | Skin protective product |
| GB2401044A (en) * | 2003-05-02 | 2004-11-03 | Julie Elizabeth Almond | Composition for treatment of skin conditions, such as sweet itch in horses, comprising an alcohol, an oil and a derivative of benzene |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2422765A (en) * | 2005-02-07 | 2006-08-09 | Donald Henry Yates | Pre-grooming preparation |
| EP1787637A2 (en) * | 2005-08-18 | 2007-05-23 | Francisco Caballero Gobern | Composition for veterinary use |
| EP1787637A3 (en) * | 2005-08-18 | 2007-09-05 | Francisco Caballero Gobern | Composition for veterinary use |
| NL2001955C (en) * | 2008-09-05 | 2010-03-15 | Eden Horse B V | Compositions for treating mud fever. |
| EP3000475A4 (en) * | 2013-05-23 | 2017-01-11 | Kledos Cell Tech, S.L. | Pharmaceutical or cosmetic composition for the regeneration and cicatrisation of the skin |
Also Published As
| Publication number | Publication date |
|---|---|
| GB0329016D0 (en) | 2004-01-14 |
| GB2409159B (en) | 2008-02-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2755596B2 (en) | Bactericidal composition and method thereof | |
| JP4176227B2 (en) | Antimicrobial composition | |
| US8101163B2 (en) | Transdermal compositions | |
| US7632871B2 (en) | Methods of making and methods of using antiseptic disinfectant, cosmetic and toiletries, medicine or food containing the same | |
| CN101703453B (en) | Enzyme containing oral composition having enhanced stability | |
| JP3657520B2 (en) | Toothpaste composition containing rose seed oil (Toothpaste-compositioning contansing roseseedoil) | |
| WO2005009454A1 (en) | Periodontal disease therapeutic and/or preventive composition | |
| EP1824565B1 (en) | Oral compositions for prevention and reduction of bacterial adhesion to oral surfaces | |
| US20080145461A1 (en) | Formulation and method of making a topical pain relief composition | |
| KR101308959B1 (en) | Low-Irritative Powder Composition for Washing | |
| GB2409159A (en) | A preparation for treating mud fever in horses | |
| DE69823187T2 (en) | A COMPOSITION COMPRISING AN N-ANDECYLENOYL AMINO-SUBSTRATE; APPLICATION IN COSMETICS | |
| CN107582419B (en) | A kind of mouthwash containing biological lysozyme | |
| WO2014036564A1 (en) | Oral care composition for promoting and maintaining oral health and method of forming and using same | |
| JP3008525B2 (en) | Oral composition | |
| US20040013622A1 (en) | Cosmetic compositions for improving the health of nails | |
| US5648397A (en) | Pharmaceutical composition and methods for using it | |
| JP4625625B2 (en) | Disinfectant and composition for oral cavity containing the disinfectant | |
| JPH045222A (en) | Crude drug extract for oral cavity and composition for oral cavity containing the same as active ingredient | |
| AU2006235798A1 (en) | Topical composition | |
| JP4011787B2 (en) | Selective antimicrobial composition | |
| WO2003097000A1 (en) | Composition for enhancing oral health | |
| KR102630903B1 (en) | New uses | |
| EP0987942A1 (en) | Pharmaceutical composition and methods for using it | |
| JPH03157311A (en) | Cosmetic for common acne |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 732E | Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977) |
Free format text: REGISTERED BETWEEN 20111208 AND 20111214 |
|
| 732E | Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977) |
Free format text: REGISTERED BETWEEN 20140206 AND 20140212 |
|
| PE20 | Patent expired after termination of 20 years |
Expiry date: 20231214 |