GB2225017B - Immobilization of proteins on solid carriers - Google Patents

Immobilization of proteins on solid carriers

Info

Publication number
GB2225017B
GB2225017B GB8925240A GB8925240A GB2225017B GB 2225017 B GB2225017 B GB 2225017B GB 8925240 A GB8925240 A GB 8925240A GB 8925240 A GB8925240 A GB 8925240A GB 2225017 B GB2225017 B GB 2225017B
Authority
GB
United Kingdom
Prior art keywords
immobilization
proteins
solid carriers
carriers
solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8925240A
Other versions
GB2225017A (en
GB8925240D0 (en
Inventor
Eran Hadas
Rela Koppel
Gideon Fleminger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roehm GmbH
Roehm GmbH Darmstadt
Original Assignee
Roehm GmbH
Roehm GmbH Darmstadt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roehm GmbH, Roehm GmbH Darmstadt filed Critical Roehm GmbH
Publication of GB8925240D0 publication Critical patent/GB8925240D0/en
Publication of GB2225017A publication Critical patent/GB2225017A/en
Application granted granted Critical
Publication of GB2225017B publication Critical patent/GB2225017B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GB8925240A 1988-11-18 1989-11-08 Immobilization of proteins on solid carriers Expired - Lifetime GB2225017B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3839020A DE3839020A1 (en) 1988-11-18 1988-11-18 FIXING OF PROTEINS ON SOLID CARRIERS

Publications (3)

Publication Number Publication Date
GB8925240D0 GB8925240D0 (en) 1989-12-28
GB2225017A GB2225017A (en) 1990-05-23
GB2225017B true GB2225017B (en) 1992-09-09

Family

ID=6367420

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8925240A Expired - Lifetime GB2225017B (en) 1988-11-18 1989-11-08 Immobilization of proteins on solid carriers

Country Status (6)

Country Link
CH (1) CH679399A5 (en)
DE (1) DE3839020A1 (en)
FR (1) FR2639357B1 (en)
GB (1) GB2225017B (en)
IT (1) IT1233901B (en)
SE (1) SE8903726L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9014689D0 (en) * 1990-07-02 1990-08-22 Tioxide Group Services Ltd Supports for active entities

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1290702A (en) * 1968-09-27 1972-09-27
WO1987004726A1 (en) * 1986-02-03 1987-08-13 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853708A (en) * 1970-01-23 1974-12-10 Exploaterings Ab Tbf Coupling biologically active substances to oxirane-containing polymers
SU443902A1 (en) * 1973-09-13 1974-09-25 Таллинский Политехнический Институт The method of obtaining enzymes immobilized in the structure of polymerization gels
DE2722751C2 (en) * 1977-05-20 1990-06-21 Röhm GmbH, 6100 Darmstadt Bead polymer with a particle diameter of 5 to 1000 μm and an internal cavity
US4652524A (en) * 1980-10-02 1987-03-24 Ivan E. Modrovich Soluble stabilized enzymes
DE3135541A1 (en) * 1981-09-08 1983-03-24 Bayer Ag, 5090 Leverkusen Derivatives of kallikrein-trypsin inhibitor (BPTI), carrier-bound BPTI derivatives, their preparation and their use for preparing the enzymes trypsin, chymotrypsin and kallikrein in pure form
CA1203164A (en) * 1982-03-09 1986-04-15 Thomas J. Mckearn Antibody conjugates

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1290702A (en) * 1968-09-27 1972-09-27
WO1987004726A1 (en) * 1986-02-03 1987-08-13 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof

Also Published As

Publication number Publication date
GB2225017A (en) 1990-05-23
DE3839020A1 (en) 1990-05-23
IT8967810A0 (en) 1989-09-28
SE8903726D0 (en) 1989-11-07
IT1233901B (en) 1992-04-21
FR2639357A1 (en) 1990-05-25
FR2639357B1 (en) 1994-07-29
SE8903726L (en) 1990-05-19
CH679399A5 (en) 1992-02-14
GB8925240D0 (en) 1989-12-28

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19961108