GB2213152B - New derivatives of 3-piperidine carbaldehyde oxime, their preparation and their use as medicaments - Google Patents

New derivatives of 3-piperidine carbaldehyde oxime, their preparation and their use as medicaments

Info

Publication number
GB2213152B
GB2213152B GB8830390A GB8830390A GB2213152B GB 2213152 B GB2213152 B GB 2213152B GB 8830390 A GB8830390 A GB 8830390A GB 8830390 A GB8830390 A GB 8830390A GB 2213152 B GB2213152 B GB 2213152B
Authority
GB
United Kingdom
Prior art keywords
medicaments
preparation
new derivatives
carbaldehyde oxime
piperidine carbaldehyde
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8830390A
Other languages
English (en)
Other versions
GB2213152A (en
GB8830390D0 (en
Inventor
Giulio Galliani
Fernando Barzaghi
Carla Bonetti
Emilio Toja
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of GB8830390D0 publication Critical patent/GB8830390D0/en
Publication of GB2213152A publication Critical patent/GB2213152A/en
Application granted granted Critical
Publication of GB2213152B publication Critical patent/GB2213152B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
GB8830390A 1987-12-30 1988-12-30 New derivatives of 3-piperidine carbaldehyde oxime, their preparation and their use as medicaments Expired - Fee Related GB2213152B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8723280A IT1233446B (it) 1987-12-30 1987-12-30 Derivati della 3 piperidinocarbaldeide ossima, loro procedimento di preparazione e loro applicazione come farmaci

Publications (3)

Publication Number Publication Date
GB8830390D0 GB8830390D0 (en) 1989-03-01
GB2213152A GB2213152A (en) 1989-08-09
GB2213152B true GB2213152B (en) 1991-04-24

Family

ID=11205608

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8830390A Expired - Fee Related GB2213152B (en) 1987-12-30 1988-12-30 New derivatives of 3-piperidine carbaldehyde oxime, their preparation and their use as medicaments

Country Status (9)

Country Link
US (1) US4927837A (en, 2012)
JP (1) JPH01203361A (en, 2012)
CH (1) CH675998A5 (en, 2012)
DE (1) DE3844415A1 (en, 2012)
ES (1) ES2009689A6 (en, 2012)
FR (1) FR2625502B1 (en, 2012)
GB (1) GB2213152B (en, 2012)
IT (1) IT1233446B (en, 2012)
NL (1) NL8803210A (en, 2012)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
AU3301689A (en) * 1988-04-15 1989-10-26 Beecham Group Plc 1-azabicyclo-alkyl derivatives
DK0392803T3 (da) * 1989-04-13 2004-10-18 Beecham Group Plc Hidtil ukendte forbindelser
IT1240603B (it) * 1990-03-14 1993-12-17 Roussel Maestretti Spa Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale
PT98742A (pt) * 1990-08-24 1992-07-31 Beecham Group Plc Processo para a preparacao de compostos azabicilicos
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
JPH06501933A (ja) * 1990-10-12 1994-03-03 ビーチャム・グループ・パブリック・リミテッド・カンパニー １，２，５，６−テトラヒドロピリジン・オキシム誘導体
DE69817557T2 (de) 1997-05-14 2004-06-17 Neurosearch A/S Piperidine derivate als inhibitoren der neurotransmitter-wiederaufbaunahme

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3004979A (en) * 1961-10-17 Oximes of certain tetrahydropyridine
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
US4408054A (en) * 1981-11-12 1983-10-04 Hoechst-Roussel Pharmaceuticals Inc. Oximes of 4-benzoyl-piperidines
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents

Also Published As

Publication number Publication date
CH675998A5 (en, 2012) 1990-11-30
IT8723280A0 (it) 1987-12-30
FR2625502A1 (fr) 1989-07-07
GB2213152A (en) 1989-08-09
FR2625502B1 (fr) 1992-11-06
ES2009689A6 (es) 1989-10-01
JPH01203361A (ja) 1989-08-16
IT1233446B (it) 1992-04-01
GB8830390D0 (en) 1989-03-01
NL8803210A (nl) 1989-07-17
DE3844415A1 (de) 1989-07-13
US4927837A (en) 1990-05-22

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19951230