GB2175901B - Water soluble salt of minoxidil and its use in treating hair loss - Google Patents

Water soluble salt of minoxidil and its use in treating hair loss

Info

Publication number
GB2175901B
GB2175901B GB08612461A GB8612461A GB2175901B GB 2175901 B GB2175901 B GB 2175901B GB 08612461 A GB08612461 A GB 08612461A GB 8612461 A GB8612461 A GB 8612461A GB 2175901 B GB2175901 B GB 2175901B
Authority
GB
United Kingdom
Prior art keywords
minoxidil
water soluble
soluble salt
hair loss
treating hair
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08612461A
Other languages
English (en)
Other versions
GB8612461D0 (en
GB2175901A (en
Inventor
Schiena Michele G Di
Vittoria Orru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Serono OTC SA
Original Assignee
Serono OTC SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serono OTC SA filed Critical Serono OTC SA
Publication of GB8612461D0 publication Critical patent/GB8612461D0/en
Publication of GB2175901A publication Critical patent/GB2175901A/en
Application granted granted Critical
Publication of GB2175901B publication Critical patent/GB2175901B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
GB08612461A 1985-05-22 1986-05-22 Water soluble salt of minoxidil and its use in treating hair loss Expired GB2175901B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8520836A IT1214610B (it) 1985-05-22 1985-05-22 Composto per uso cosmetico dermatologico e relative composizioni.

Publications (3)

Publication Number Publication Date
GB8612461D0 GB8612461D0 (en) 1986-07-02
GB2175901A GB2175901A (en) 1986-12-10
GB2175901B true GB2175901B (en) 1988-09-21

Family

ID=11172771

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08612461A Expired GB2175901B (en) 1985-05-22 1986-05-22 Water soluble salt of minoxidil and its use in treating hair loss

Country Status (7)

Country Link
JP (1) JPH0651616B2 (enrdf_load_stackoverflow)
CH (1) CH667651A5 (enrdf_load_stackoverflow)
DE (1) DE3617124A1 (enrdf_load_stackoverflow)
FR (1) FR2582304B1 (enrdf_load_stackoverflow)
GB (1) GB2175901B (enrdf_load_stackoverflow)
IL (2) IL78842A0 (enrdf_load_stackoverflow)
IT (1) IT1214610B (enrdf_load_stackoverflow)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300510A (en) * 1988-09-23 1994-04-05 Norchim Salt of 6-piperidino-2,4-diaminopyrimidine 3-oxide and aceturic acid, its preparation and its dermato-cosmetological application
FR2636840B1 (fr) * 1988-09-23 1990-12-21 Norchim Sarl Sel du 6-piperidino-2,4-diaminopyrimidine-3-oxyde et de l'acide aceturique, leur preparation et leur application dermatocosmetologiques
FR2706896B1 (enrdf_load_stackoverflow) * 1993-06-23 1996-04-12 Caillot Jean Luc

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2188599A5 (en) * 1972-06-12 1974-01-18 Fabre Sa Pierre (Pyro)glutamic acid derivs - from (substd) ethylenediamine, substd guanidine and dimethyl amino ethanol
LU73680A1 (enrdf_load_stackoverflow) * 1975-10-29 1977-05-31
US4139619A (en) * 1976-05-24 1979-02-13 The Upjohn Company 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth
GB2140257B (en) * 1980-12-04 1985-09-18 Quantel Ltd Video image creation
EP0093770B1 (en) * 1981-11-09 1991-06-19 BAZZANO, Gail S The use of retinoids and minoxidil (2,4-diamino-6-piperidino-pyrimidine-3-oxide) to increase the rate of growth of human scalp hair and to treat certain types of alopecias
JPS5888307A (ja) * 1981-11-19 1983-05-26 Takeo Kinji ミノキシジル配合養毛剤
JPS5888306A (ja) * 1981-11-19 1983-05-26 Takeo Kinji 養毛化粧料
US4452989A (en) * 1982-06-01 1984-06-05 Charles Of The Ritz Group Ltd. Substantive moisturizing derivatives of 2-pyrrolidone-5-carboxylic acid and compositions containing same

Also Published As

Publication number Publication date
JPH0651616B2 (ja) 1994-07-06
IT8520836A0 (it) 1985-05-22
FR2582304B1 (fr) 1989-06-02
DE3617124C2 (enrdf_load_stackoverflow) 1992-07-16
GB8612461D0 (en) 1986-07-02
FR2582304A1 (fr) 1986-11-28
IL78842A0 (en) 1986-09-30
GB2175901A (en) 1986-12-10
IT1214610B (it) 1990-01-18
DE3617124A1 (de) 1986-11-27
IL78842A (en) 1989-09-28
CH667651A5 (de) 1988-10-31
JPS6269A (ja) 1987-01-06

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Legal Events

Date Code Title Description
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19990522