GB2154578A - Novel 1,5-benzothiazepine derivatives and processes for preparing the same - Google Patents

Novel 1,5-benzothiazepine derivatives and processes for preparing the same Download PDF

Info

Publication number
GB2154578A
GB2154578A GB08404325A GB8404325A GB2154578A GB 2154578 A GB2154578 A GB 2154578A GB 08404325 A GB08404325 A GB 08404325A GB 8404325 A GB8404325 A GB 8404325A GB 2154578 A GB2154578 A GB 2154578A
Authority
GB
United Kingdom
Prior art keywords
compound
pharmaceutically acceptable
acid addition
hydrogen
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB08404325A
Other languages
English (en)
Other versions
GB8404325D0 (en
Inventor
Mikio Takeda
Tokuro Oh-Ishi
Taku Nagao
Hiromichi Nakajima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to GB08404325A priority Critical patent/GB2154578A/en
Publication of GB8404325D0 publication Critical patent/GB8404325D0/en
Priority to US06/698,125 priority patent/US4590188A/en
Priority to JP60024039A priority patent/JPS60178870A/ja
Priority to AT85101713T priority patent/ATE35543T1/de
Priority to EP85101713A priority patent/EP0154838B1/en
Priority to DE8585101713T priority patent/DE3563623D1/de
Priority to CA000474421A priority patent/CA1239399A/en
Priority to KR1019850000967A priority patent/KR900001163B1/ko
Publication of GB2154578A publication Critical patent/GB2154578A/en
Priority to CA000523504A priority patent/CA1238635A/en
Priority to SG57/89A priority patent/SG5789G/en
Priority to HK327/89A priority patent/HK32789A/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08404325A 1984-02-18 1984-02-18 Novel 1,5-benzothiazepine derivatives and processes for preparing the same Withdrawn GB2154578A (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
GB08404325A GB2154578A (en) 1984-02-18 1984-02-18 Novel 1,5-benzothiazepine derivatives and processes for preparing the same
US06/698,125 US4590188A (en) 1984-02-18 1985-02-04 1,5-benzothiazepine derivatives and their pharmaceutical use
JP60024039A JPS60178870A (ja) 1984-02-18 1985-02-08 1,5‐ベンゾチアゼピン誘導体及びその製法
CA000474421A CA1239399A (en) 1984-02-18 1985-02-15 1,5-benzothiazepine derivatives and processes for preparing the same
EP85101713A EP0154838B1 (en) 1984-02-18 1985-02-15 Novel 1,5-benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions
AT85101713T ATE35543T1 (de) 1984-02-18 1985-02-15 1,5-benzothiazepinderivate, verfahren zu ihrer herstellung und arzneimittel.
DE8585101713T DE3563623D1 (en) 1984-02-18 1985-02-15 Novel 1,5-benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions
KR1019850000967A KR900001163B1 (ko) 1984-02-18 1985-02-16 1,5-벤조티아제핀 유도체의 제조방법
CA000523504A CA1238635A (en) 1984-02-18 1986-11-20 1,5-benzothiazepine derivatives and processes for preparing the same
SG57/89A SG5789G (en) 1984-02-18 1989-02-03 Novel 1,5-benzothiazepine derivatives,processes for preparing the same and pharmaceutical compositions
HK327/89A HK32789A (en) 1984-02-18 1989-04-20 Novel 1,5-benzothiazepine derivatives,processes for preparing the same and pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08404325A GB2154578A (en) 1984-02-18 1984-02-18 Novel 1,5-benzothiazepine derivatives and processes for preparing the same

Publications (2)

Publication Number Publication Date
GB8404325D0 GB8404325D0 (en) 1984-03-21
GB2154578A true GB2154578A (en) 1985-09-11

Family

ID=10556824

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08404325A Withdrawn GB2154578A (en) 1984-02-18 1984-02-18 Novel 1,5-benzothiazepine derivatives and processes for preparing the same

Country Status (2)

Country Link
JP (1) JPS60178870A (pl)
GB (1) GB2154578A (pl)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822789A (en) * 1987-02-10 1989-04-18 Tanabe Seiyaku Co., Ltd. Method of producing renal function-improving effect and diuretic effect on warm-blooded animal
GB2231329B (en) * 1988-06-20 1992-10-21 Squibb & Sons Inc Benzazepine and benzothiazepine derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822789A (en) * 1987-02-10 1989-04-18 Tanabe Seiyaku Co., Ltd. Method of producing renal function-improving effect and diuretic effect on warm-blooded animal
AU603421B2 (en) * 1987-02-10 1990-11-15 Tanabe Seiyaku Co., Ltd. Agent having renal function-improving effect and diuretic effect
GB2231329B (en) * 1988-06-20 1992-10-21 Squibb & Sons Inc Benzazepine and benzothiazepine derivatives

Also Published As

Publication number Publication date
GB8404325D0 (en) 1984-03-21
JPH0421667B2 (pl) 1992-04-13
JPS60178870A (ja) 1985-09-12

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)