GB2153669A - A fodder concentrate having weight-gain increasing effect - Google Patents
A fodder concentrate having weight-gain increasing effect Download PDFInfo
- Publication number
- GB2153669A GB2153669A GB08500142A GB8500142A GB2153669A GB 2153669 A GB2153669 A GB 2153669A GB 08500142 A GB08500142 A GB 08500142A GB 8500142 A GB8500142 A GB 8500142A GB 2153669 A GB2153669 A GB 2153669A
- Authority
- GB
- United Kingdom
- Prior art keywords
- weight
- propylene glycol
- concentrate
- per cent
- fodder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/28—Silicates, e.g. perlites, zeolites or bentonites
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Abstract
A fodder concentrate having weight-gain increasing effect comprises 2-formyl-quinoxaline-1, 4-dioxide carbomethoxyhydrazone (carbadox) and propylene glycol which is bound to a solid carrier consisting of magnesium oxide, magnesium carbonate, magnesium peroxide and/or silica and containing 25 to 75 percent by weight of propylene glycol, calculated on the total amount of carrier and propylene glycol. Due to the presence of the solid carrier comprising propylene glycol the explosion risk connected with the treatment of carbadox is completely eliminated.
Description
SPECIFICATION
A fodder concentrate having weight-gain increasing effect
The invention relates to a fodder concentrate having weight-gain increasing effect and comprising 1 to 25 per cent by weight of 24ormyl-quinoxaline-1,4- dioxide carbomethoxyhydrazone (carbadox), propylene glycol and the usual components of fodder concentrates.
Most of the known processes for the preparation of carbadox furnish crystal needles of 1 to 200 im length which are apt to crumbling [e.g. BE-P No.
669,353 and US-P No. 3,493,572]. When producing a fodder concentrate, the treatment of carbadox can lead even to explosion, owing to the formation of carbadox dust. According to BE-P No. 833,441 the explosion risk is avoided by blending the components of the fodder concentrate in the presence of 2 to 8 per cent by weight of a non-toxic oil, preferably soya oil, maize oil or mineral oil. However, the oil introduced into the concentrate becomes easily rancid, thus, the fodder concentrate can be stored only for a relatively short time since otherwise the animal feed prepared from it will be uneatable for pigs. A further difficulty during blending is that the oil used does not dissolve and barely wets the active substance, i.e. carbadox.
According to BE-P No. 854,945, amorphous carbadox crystals of 30 to 100 Wm length which comprise 15 to 40 per cent by weight of water are employed for the preparation of a fodder concentrate. In every other respect the process of BE-P No.833,441 is followed. Thus, the explosion risk connected with the treatment of carbadox is tried to be eliminated through a water content of 15 to 40 per cent by weight, the use of a non-toxic oil and of medium crystal size. However, the water content of the actiye substance favours to germ growth, and in the presence of it the oil becomes easily rancid.
In accordance with HU-P No. 178,838, amorphous carbadox crystals precipitated from an aqueous medium according to HU-P No. 171,738 and having a length of 10 to 60 yam are blended with the other components of the fodder concentrate in the presence of propylene glycol. In this way, the sensitiveness of carbadox to spark is considerably lowered. A drawback of the above process is that a relatively low quantity of liquid propylene glycol must be admixed to a high quantity of solid substance.
However, homogeneous mixtures cannot be obtained by means of the available economical blenders equipped with spraying nozzles, and in some cases the product is sticky and contains clots.
In addition, the water content of the fodder concentrate can be enhanced owing to the high hygroscopicity of the propylene glycol, thus, germ growth is promoted, too.
Now it has been found that the defects listed above can be eliminated by the fodder concentrate of the invention that comprises 1 to 25 per cent by weight of carbadox, furthermore propylene glycol and the usual components of fodder concentrates, wherein the propylene glycol is bound to a solid carrier consisting of magnesium oxide, magnesium carbonate, magnesium peroxide and/or silica and contains 25 to 75 per cent by weight of propylene glycol calculated on the total amount of carrier and propylene glycol.
The carrier comprising propylene glycol is prepared by admixing 25 to 75 per cent by weight of propylene glycol to 75 to 25 per cent by weight of magnesium oxide and/or magnesium peroxide andi or magnesium carbonate and/or silica, preferably by spraying. In general, 80 per cent of the solid carrier are smaller than 10 lim in particle size. The average particle size of the solid carrier is preferably 1 to 5 Fm. The thus-obtained solid mixture of high propylene glycol content can be treated like solid propylene glycol during mixing and does not deliquesce even when it is stored on air of 75 per cent relative humidity for a long time such as 30 days.
Preferred carrier is the magnesium carbonate or a mixture of magnesium carbonate and silica or magnesium oxide and silica.
The fodder concentrate of the invention is prepared by admixing carbadox to the usual components of fodder concentrates in the presence of the solid carrier comprising propylene glycol to obtain a carbadox content of 1 to 25 per cent by weight. The amount of the carrier comprising propylene glycol in the fodder concentrate is, in general, 1 to 15 per cent by weight, preferably 2 to 8 per cent by weight.
It is preferable to admix the carbadox as the last component to the mixture of the other constituents of the concentrate, then to add a portion of the carbadox, again a portion of the solid carriercom- prising propylene glycol, then further carbadox and so on.
The usual constituents of fodder concentrates are as follows: carriers such as alfalfa meal, wheat fodder meal, wheat bran, rice bran of reduced oil content, maize meal, soya meal, wheat starch, maize starch, kaolin, calcium carbonate etc.; additives, e.g.
antioxidants, preservatives, microelements, vitamins and salts such as sodium chloride, magnesium chloride, magnesium sulfate, iron salts etc.
The fodder concentrate of the invention can be diluted with the usual constituents of animal feeds to give a feed comprising, in general, 0.001 to 0.0075 per cent by weight of carbadox. The animal feed obtained is suitable forfeeding pigs.
The fodder concentrate of the invention can be easily manufactured by means of a conventional blender. The fodder concentrate is not hygroscopic, thus, it can be stored for a long time without any damage.
Due to the presence of the solid carrier comprising propylene glycol, the explosion risk connected with the treatment of carbadox is completely eliminated.
This explosion risk can be characterized by the sensitiveness to spark, i.e. the minimum energy value that can produce a spark discharge leading to ignition. Thus, this value is a measure of fire and explosion risk attributed to electrostatic charging.
The sensitiveness of carbadox to spark was determined according to Hungarian Standard No. 16040.
In case of floating carbadox powder the value of sensitiveness to spark is equivalent to 5 mJ. In case of a fodder concentrate comprising carbadox powder and liquid propylene glycol the value of sensitiveness to spark is 350 mJ. In case of the fodder concentrate of the invention the sensitiveness to spark is 500 mJ. (The higher is this value, the lower is the explosion risk.) From the above values it can be seen that the sensitiveness of carbadox to spark has a much highervalue in the presence of "solid" propylene glycol than in the presence of the common liquid propylene glycol.
The invention is further elucidated by means of the following Examples.
Bonding propylene glycol to the solid carrier
40 parts by weight of magnesium carbonate (average particle size: 1 to 2 I*m,80 per cent of the particles have a size of 0.5 to 5 Fm) are transferred into an eddy current blender of type Lodge equipped with spraying nozzles. Mixing is started and 50 parts by weight of propylene glycol are sprayed at a steady rate. After completing the spraying, mixing is continued for a further hour, then 10 parts by weight of finely divided silica are added and the mixture is homogenized for further 10 minutes. The mixture obtained contains 50 per cent by weight of propylene glycol, 40 per cent by weight of magnesium carbonate and 10 per cent by weight of silica.
The following powder mixtures are prepared in a similar way:
60 per cent by weight of propylene glycol +
40 per cent by weight of magnesium oxide;
70 per cent by weight of propylene glycol + 30 per cent by weight of magnesium carbonate;
52 per cent by weight of propylene glycol +
48 per cent by weight of magnesium peroxide;
75 per cent by weight of propylene glycol +
25 per cent by weight of silica;
50 per cent by weight of propylene glycol + 50 per cent by weight of magnesium carbonate;
25 per cent by weight of propylene glycol +
60 per cent by weight of magnesium carbonate + 15 per cent by weight of silica.
Example 1
Into a blender of 1 m3 capacity, 420 kg of alfalfa meal,182 of or wheat starch, kg of a powder mixture comprising 50 per cent by weight of propylene glycol, 40 per cent by weight of magnesium carbonate and 10 per cent by weight of silica, then 70 kg of carbadox are introduced under stirring.
Homogenization is continued for further 8 minutes.
700 kg of fodder concentrate are obtained that contains 10 per cent by weight of carbadox.
Example 2
480 kg of extracted sunflower meal, 480 kg of maize flake, 30 kg of a powder mixture comprising 60 per cent by weight of propylene glycol and 40 per cent by weight of magnesium oxide, then 10 kg of carbadox are homogenized.
1000 kg of fodder concentrate are obtained that contains 1 per cent by weight of carbadox.
Example 3
300 kg of dried sugar-beet slice meal,100 of trefoil meal, 40 kg of a powder mixture comprising 50 per cent by weight of propylene glycol and 50 per cent by weight of magnesium carbonate, then 60 kg of carbadox are homogenized as described in Example 1.500 kg of fodder concentrate are obtained that contains 12 per cent by weight of carbadox.
Example 4
into the blender used in Example 1,280 kg of barley meal,140 of or potato starch, kg of a powder mixture comprising 70 per cen by weight of propylene glycol and 30 per cent by weight of magnesium carbonate and then 80 kg of carbadox are introduced under mixing. The components are homogenized for further 10 minutes, then again 55 kg of a powder mixture comprising 70 per cent by weight of propylene glycol and 30 per cent by weight of magnesium carbonate and 95 kg of carbadox are added. Homogenization is continued for further 12 minutes. 700 kg of a concentrate are obtained that contains 25 per cent by weight of carbadox.
Example 5
350 kg of oatmeal, 250 kg of maize starch of reduced oil content, 30 kg of powder mixture comprising 52 per cent by weight of propylene glycol and 48 per cent by weight of magnesium peroxide and 70 kg of carbadox are homogenized as described in Example 1.
700 kg of a fodder concentrate are obtained that contains 10 per cent by weight of carbadox.
Example 6 10 g of the concentrate of Example 1 are admixed to the following components: 19.9 kg of maize meal, 5 kg of wheat meal, kg of barley meal, kg of oatmeal, 2 kg of bran, 16 kg of extracted soya, 4 kg of fish meal, 20 kg of milk powder, kg of fat powder and 4 kg of a mixture comprising mineral subst ances, vitamins and microelements. 100kg of or an animal feed are obtained that contains 0.001 per cent by weight of carbadox.
Example 7
75 g of the concentrate of Example 2 are admixed to the following components: 37.825 kg of maize meal, kg of wheat meal, 25 kg of barley meal, 5 kg of oatmeal,2.4 of or bran, 13 kg of extracted soya, 6 kg of fish meal,1.5 of or fat powder, 1 kg of fodder lime,0.5 of or fodder salt and 1.7 kg of a mixture comprising mineral substances, vitamins and microelements.
100 kg of an animal feed are obtained that contains 0.0075 per cent by weight of carbadox.
Claims (7)
1. A fodder concentrate having weight-gain increasing effect and comprising 2-formyl quinoxaline-l ,4-dioxide carbomethoxy-hydrazone (carbadox), propylene glycol and one or more components usually present in fodder concentrates, in which the propylene glycol is bound to a solid carrier consisting of magnesium oxide, magnesium carbonate, magnesium peroxide and/or silica and preferably containing 25 to 75 per cent by weight of propylene glycol, calculated on the total amount of carrier and propylene glycol.
2. A fodder concentrate as claimed in claim 1, in which the propylene glycol is bound to magnesium carbonate.
3. A fodder concentrate as claimed in claim 1 in which the propylene glycol is bound to a mixture of magnesium carbonate and silica or magnesium oxide and silica.
4. A concentrate as claimed in any one of claims 1 to 3, wherein the amount of carbadox in the concentrate is 1 to 25% by weight.
5. A concentrate substantially as hereinbefore described in any one of Examples 1 to 5.
6. A fodder containing a concentrate as claimed in any one of claims 1 to 5.
7. A fodder substantially as hereinbefore described in Example 6 or Example 7.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU8441A HU190866B (en) | 1984-01-06 | 1984-01-06 | Process for producing concentratum increasing the weight output and containing agent of 1-25 mass pct. and/or animal food containing agent of 0,001-0,075 mass pct. |
Publications (3)
Publication Number | Publication Date |
---|---|
GB8500142D0 GB8500142D0 (en) | 1985-02-13 |
GB2153669A true GB2153669A (en) | 1985-08-29 |
GB2153669B GB2153669B (en) | 1987-05-28 |
Family
ID=10947615
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB08500142A Expired GB2153669B (en) | 1984-01-06 | 1985-01-04 | A fodder concentrate having weight-gain increasing effect |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS60214847A (en) |
BE (1) | BE901435A (en) |
DE (1) | DE3500158A1 (en) |
FR (1) | FR2557771A1 (en) |
GB (1) | GB2153669B (en) |
HU (1) | HU190866B (en) |
SU (1) | SU1435142A3 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4600586A (en) * | 1983-08-08 | 1986-07-15 | Green Milton L | Livestock feed lot adaptation composition and method |
HU191245B (en) * | 1984-01-06 | 1987-01-28 | Egis Gyogyszergyar,Hu | Process for the production of stbale pharmaceutical preparation against ketosis |
HU191244B (en) * | 1984-01-06 | 1987-01-28 | Egyt Gyogyszervegyeszeti Gyar | Dust mixture of high propylene-glycol content and process for producing same |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE41502B1 (en) * | 1974-09-23 | 1980-01-16 | Pfizer | Process for the preparation of dustless quinoxaline-1,4-dioxide animal feed supplement premixes |
DE2518189A1 (en) * | 1975-04-24 | 1976-11-04 | Astra Ewos Ab | Trace element concentrate for animal feeds - heavy mineral substance coated with binder which contains trace elements |
DE2819830C2 (en) * | 1978-05-05 | 1984-10-18 | geb. Furman Larisa Abramovna Moskau / Moskva Akerman | Preparation for intensifying the feed conversion of cattle and poultry on the basis of perchlorates and process for its production |
-
1984
- 1984-01-06 HU HU8441A patent/HU190866B/en not_active IP Right Cessation
-
1985
- 1985-01-03 BE BE1/11166A patent/BE901435A/en not_active IP Right Cessation
- 1985-01-04 FR FR8500065A patent/FR2557771A1/en not_active Withdrawn
- 1985-01-04 SU SU853857906A patent/SU1435142A3/en active
- 1985-01-04 GB GB08500142A patent/GB2153669B/en not_active Expired
- 1985-01-04 JP JP60000022A patent/JPS60214847A/en active Granted
- 1985-01-04 DE DE19853500158 patent/DE3500158A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
SU1435142A3 (en) | 1988-10-30 |
HU190866B (en) | 1986-11-28 |
BE901435A (en) | 1985-07-03 |
GB2153669B (en) | 1987-05-28 |
DE3500158A1 (en) | 1985-07-18 |
HUT37337A (en) | 1985-12-28 |
FR2557771A1 (en) | 1985-07-12 |
JPS60214847A (en) | 1985-10-28 |
GB8500142D0 (en) | 1985-02-13 |
JPH0257900B2 (en) | 1990-12-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |