GB2153359B - Side-chain unsaturated 1-hydroxyvitamin d compounds - Google Patents

Side-chain unsaturated 1-hydroxyvitamin d compounds

Info

Publication number
GB2153359B
GB2153359B GB08502163A GB8502163A GB2153359B GB 2153359 B GB2153359 B GB 2153359B GB 08502163 A GB08502163 A GB 08502163A GB 8502163 A GB8502163 A GB 8502163A GB 2153359 B GB2153359 B GB 2153359B
Authority
GB
United Kingdom
Prior art keywords
hydroxyvitamin
compounds
chain unsaturated
unsaturated
chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08502163A
Other languages
English (en)
Other versions
GB8502163D0 (en
GB2153359A (en
Inventor
Hector F Deluca
Heinrich K Schnoes
Rafal R Sicinski
Yoko Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of GB8502163D0 publication Critical patent/GB8502163D0/en
Publication of GB2153359A publication Critical patent/GB2153359A/en
Application granted granted Critical
Publication of GB2153359B publication Critical patent/GB2153359B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
GB08502163A 1984-01-30 1985-01-29 Side-chain unsaturated 1-hydroxyvitamin d compounds Expired GB2153359B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57511684A 1984-01-30 1984-01-30

Publications (3)

Publication Number Publication Date
GB8502163D0 GB8502163D0 (en) 1985-02-27
GB2153359A GB2153359A (en) 1985-08-21
GB2153359B true GB2153359B (en) 1987-08-12

Family

ID=24299022

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08502163A Expired GB2153359B (en) 1984-01-30 1985-01-29 Side-chain unsaturated 1-hydroxyvitamin d compounds

Country Status (11)

Country Link
JP (1) JPS61501146A (ja)
AU (1) AU589113B2 (ja)
BE (1) BE901602A (ja)
CH (1) CH667087A5 (ja)
DE (2) DE3590020C2 (ja)
DK (1) DK437585D0 (ja)
FR (1) FR2558830B1 (ja)
GB (1) GB2153359B (ja)
IE (1) IE57947B1 (ja)
NL (1) NL8520003A (ja)
WO (1) WO1985003299A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6421A (en) * 1987-02-27 1989-01-05 Teijin Ltd Preventive for osteoporosis
CA2166898C (en) * 1993-07-09 2004-09-07 Roger Bouillon Novel structural analogues of vitamin d

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697559A (en) * 1971-02-25 1972-10-10 Wisconsin Alumni Res Found 1,25-dihydroxycholecalciferol
US3741996A (en) * 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol
US3907843A (en) * 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4264513A (en) * 1979-05-21 1981-04-28 Wisconsin Alumni Research Foundation 1α-hydroxy-25-keto-27-nor-cholecalciferol and processes for preparing same
NL8320218A (nl) * 1982-07-26 1984-06-01 Wisconsin Alumni Res Found Nieuwe vitamine d analogen.
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
DE3590021C2 (de) * 1984-01-30 1992-09-10 Wisconsin Alumni Res Found 1alpha-Hydroxyvitamin D-Derivat und dieses enthaltendes Arzneimittel

Also Published As

Publication number Publication date
JPS61501146A (ja) 1986-06-12
FR2558830B1 (fr) 1987-11-20
AU3831785A (en) 1985-08-09
JPH0455424B2 (ja) 1992-09-03
IE57947B1 (en) 1993-05-19
NL8520003A (nl) 1985-12-02
IE850212L (en) 1985-07-30
DK437585A (da) 1985-09-27
AU589113B2 (en) 1989-10-05
CH667087A5 (de) 1988-09-15
WO1985003299A1 (en) 1985-08-01
GB8502163D0 (en) 1985-02-27
BE901602A (fr) 1985-05-17
FR2558830A1 (fr) 1985-08-02
DE3590020T1 (de) 1986-01-23
GB2153359A (en) 1985-08-21
DK437585D0 (da) 1985-09-27
DE3590020C2 (de) 1995-03-09

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19980129