GB2126236B - Production of antibodies - Google Patents

Production of antibodies

Info

Publication number
GB2126236B
GB2126236B GB08323455A GB8323455A GB2126236B GB 2126236 B GB2126236 B GB 2126236B GB 08323455 A GB08323455 A GB 08323455A GB 8323455 A GB8323455 A GB 8323455A GB 2126236 B GB2126236 B GB 2126236B
Authority
GB
United Kingdom
Prior art keywords
antibodies
mammal
production
vaccine
hyperimmunising
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08323455A
Other versions
GB8323455D0 (en
GB2126236A (en
Inventor
Margaret Anneli Linggood
Philip Porter
Jonathan Richard Powell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unilever PLC
Original Assignee
Unilever PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever PLC filed Critical Unilever PLC
Publication of GB8323455D0 publication Critical patent/GB8323455D0/en
Publication of GB2126236A publication Critical patent/GB2126236A/en
Application granted granted Critical
Publication of GB2126236B publication Critical patent/GB2126236B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C11/00—Milk substitutes, e.g. coffee whitener compositions
    • A23C11/02—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins
    • A23C11/10—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins
    • A23C11/103—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins containing only proteins from pulses, oilseeds or nuts, e.g. nut milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L11/00—Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
    • A23L11/60—Drinks from legumes, e.g. lupine drinks
    • A23L11/65—Soy drinks
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Agronomy & Crop Science (AREA)
  • Botany (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Dairy Products (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Antibodies are produced by hyperimmunising a mammal, such as a cow, with a vaccine derived from E. coli bacteria. The bacterial strains in the vaccine are selected on the basis of their virulence characteristics, especially adhesion factors (pili), associated with gastroenteric disease in humans. The antibodies can be recovered from the mammal's milk or serum, and used in human foods.
GB08323455A 1982-09-02 1983-09-01 Production of antibodies Expired GB2126236B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8225036 1982-09-02

Publications (3)

Publication Number Publication Date
GB8323455D0 GB8323455D0 (en) 1983-10-05
GB2126236A GB2126236A (en) 1984-03-21
GB2126236B true GB2126236B (en) 1986-09-24

Family

ID=10532644

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08323455A Expired GB2126236B (en) 1982-09-02 1983-09-01 Production of antibodies

Country Status (12)

Country Link
EP (1) EP0102831B1 (en)
JP (2) JPS5973528A (en)
AT (1) ATE43500T1 (en)
AU (1) AU548623B2 (en)
CA (1) CA1219806A (en)
DE (1) DE3379937D1 (en)
DK (1) DK398683A (en)
GB (1) GB2126236B (en)
HK (1) HK91087A (en)
IE (1) IE55673B1 (en)
NZ (1) NZ205392A (en)
ZA (1) ZA836349B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK219084D0 (en) * 1984-05-02 1984-05-02 Frederik Carl Peter Lindberg ANTIGEN
JPS6399020A (en) * 1986-06-05 1988-04-30 ベイラ−　カレツジ　オブ　メデイシン Vaccine and manufacture
US4725435A (en) * 1986-06-18 1988-02-16 Bactex, Inc. Vaccine composition for immunization against urinary tract infection caused by E. coli
US5106618A (en) * 1987-07-02 1992-04-21 Stolle Research And Development Corporation Method of treating protozoal gastrointestinal disorders by administering hyperimmune milk product
AU601510B2 (en) * 1987-11-06 1990-09-13 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
DE4026365A1 (en) * 1990-08-21 1992-02-27 Biotest Pharma Gmbh STERILE FILTERED COLORED MILK
US5780028A (en) * 1993-09-20 1998-07-14 Anadis Ltd. Method of obtaining immunoglobulins from colostrum and their use in pharmaceutical composition
US6471966B1 (en) 1994-02-04 2002-10-29 Industrial Farmaceutica Y De Especialidades, S.A. Type 1 and type p fimbriae-adhesins isolated from novel e. coli strains, process for their preparation and uses thereof
ES2076895B1 (en) * 1994-02-04 1996-08-16 Ind Farma Especial FIMBRIAS-ADHESINAS OF TYPE 1 AND P ISOLATED FROM NEW STRAINS OF E. COLI, PROCEDURE FOR THEIR OBTAINING AND APPLICATIONS.
US5707678A (en) * 1995-04-12 1998-01-13 Galagen Inc. Method for microfiltration of milk or colostral whey
US5670196A (en) * 1995-04-12 1997-09-23 Galagen Inc. Method for microfiltration of milk or colostral whey
DE19641466A1 (en) * 1996-10-09 1998-04-16 Biotest Pharma Gmbh Oral use of an immunoglobulin preparation for the prevention of hemolytic uremic syndrome and a preparation therefor
EA011240B1 (en) 2002-11-25 2009-02-27 Университет Копенгагена An isolated nucleic acid molecule comprising an allele of a genetic porcine polymorphism linked to resistance to enterotoxigenic e-coli (etec) and methods for using thereof
AU2003901008A0 (en) * 2003-03-04 2003-03-20 Anadis Ltd Composition for the treatment and prevention of bacterial infections

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1472624A (en) * 1974-09-02 1977-05-04 Canadian Patents Dev Enteric disease vaccine
GB1560934A (en) * 1975-05-07 1980-02-13 Unilever Ltd Methods for the resistance of non-human mammals to gastro-intestinal disorders
JPS5842759B2 (en) * 1975-05-23 1983-09-21 カブシキガイシヤ バイオリサ−チセンタ− Cellular Xenoseizouhou
GB1553664A (en) * 1975-06-12 1979-09-26 Unilever Ltd Antigenic compositions
JPS52120116A (en) * 1976-04-02 1977-10-08 Kitasato Inst Domestic animal colitis germ inactevated vaccine
CH627079A5 (en) * 1977-04-15 1981-12-31 Nestle Sa Process for preparing a protein concentrate containing immunological factors of milk origin
JPS5781417A (en) * 1980-09-15 1982-05-21 Bactex Inc Human immunity effect imparting vaccine against escherichia coli infectious desease
DE3172030D1 (en) * 1980-09-15 1985-10-03 Bactex Inc Immunization of humans against enterotoxogenic infection by escherichia coli
JPS5784147A (en) * 1980-11-13 1982-05-26 Seiko Epson Corp Manufacture of integrated circuit

Also Published As

Publication number Publication date
JPH02160726A (en) 1990-06-20
HK91087A (en) 1987-12-11
DE3379937D1 (en) 1989-07-06
JPS5973528A (en) 1984-04-25
EP0102831B1 (en) 1989-05-31
CA1219806A (en) 1987-03-31
AU1853883A (en) 1984-03-08
EP0102831A1 (en) 1984-03-14
IE55673B1 (en) 1990-12-19
AU548623B2 (en) 1985-12-19
GB8323455D0 (en) 1983-10-05
GB2126236A (en) 1984-03-21
ZA836349B (en) 1985-04-24
DK398683D0 (en) 1983-09-01
DK398683A (en) 1984-03-03
NZ205392A (en) 1987-03-06
IE832055L (en) 1984-03-02
ATE43500T1 (en) 1989-06-15

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19980901