GB2119370B - Dimethylacetamide solvate of syn-(2-amino-thiazol-4-yl)(methoxyimino) acetic acid - Google Patents

Dimethylacetamide solvate of syn-(2-amino-thiazol-4-yl)(methoxyimino) acetic acid

Info

Publication number
GB2119370B
GB2119370B GB08308858A GB8308858A GB2119370B GB 2119370 B GB2119370 B GB 2119370B GB 08308858 A GB08308858 A GB 08308858A GB 8308858 A GB8308858 A GB 8308858A GB 2119370 B GB2119370 B GB 2119370B
Authority
GB
United Kingdom
Prior art keywords
methoxyimino
thiazol
syn
amino
acetic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08308858A
Other languages
English (en)
Other versions
GB2119370A (en
Inventor
Robert William Burchfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of GB2119370A publication Critical patent/GB2119370A/en
Application granted granted Critical
Publication of GB2119370B publication Critical patent/GB2119370B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB08308858A 1982-04-01 1983-03-30 Dimethylacetamide solvate of syn-(2-amino-thiazol-4-yl)(methoxyimino) acetic acid Expired GB2119370B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/364,356 US4426528A (en) 1982-04-01 1982-04-01 Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid

Publications (2)

Publication Number Publication Date
GB2119370A GB2119370A (en) 1983-11-16
GB2119370B true GB2119370B (en) 1985-06-05

Family

ID=23434150

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08308858A Expired GB2119370B (en) 1982-04-01 1983-03-30 Dimethylacetamide solvate of syn-(2-amino-thiazol-4-yl)(methoxyimino) acetic acid

Country Status (11)

Country Link
US (1) US4426528A (enExample)
EP (1) EP0091277B1 (enExample)
JP (1) JPS58183678A (enExample)
KR (1) KR840004090A (enExample)
CA (1) CA1194487A (enExample)
DE (1) DE3372096D1 (enExample)
DK (1) DK91383A (enExample)
GB (1) GB2119370B (enExample)
GR (1) GR79243B (enExample)
HU (1) HU186271B (enExample)
IL (1) IL68251A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6124580A (ja) * 1984-07-12 1986-02-03 Shionogi & Co Ltd アミノチアゾリルグルタル酸誘導体の製造方法
US6878827B2 (en) * 2000-12-04 2005-04-12 Fujisawa Pharmaceutical Co., Ltd. Process for producing anhydride of aminothiazole derivative
CN111548323B (zh) * 2020-05-29 2022-06-10 山东金城医药化工有限公司 氨噻肟酸的回收方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3925372A (en) 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
DK154939C (da) 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US4152433A (en) 1976-03-12 1979-05-01 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and pharmaceutical compositions
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
US4252951A (en) 1979-10-09 1981-02-24 Eli Lilly And Company Isolation of syn-7-(2-amino-4-thiazolyl)-(methoxyimino)acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid
JPS58135872A (ja) * 1981-11-13 1983-08-12 グラクソ・グル−プ・リミテツド 新規な化合物およびその製法

Also Published As

Publication number Publication date
GR79243B (enExample) 1984-10-22
GB2119370A (en) 1983-11-16
DK91383D0 (da) 1983-02-25
HU186271B (en) 1985-07-29
JPS58183678A (ja) 1983-10-26
EP0091277A2 (en) 1983-10-12
EP0091277B1 (en) 1987-06-16
IL68251A0 (en) 1983-06-15
DE3372096D1 (en) 1987-07-23
EP0091277A3 (en) 1984-12-27
CA1194487A (en) 1985-10-01
DK91383A (da) 1983-10-02
KR840004090A (ko) 1984-10-06
US4426528A (en) 1984-01-17
IL68251A (en) 1986-03-31

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee