GB2059958A - Fortimicin a and b and derivatives - Google Patents

Fortimicin a and b and derivatives Download PDF

Info

Publication number
GB2059958A
GB2059958A GB8029336A GB8029336A GB2059958A GB 2059958 A GB2059958 A GB 2059958A GB 8029336 A GB8029336 A GB 8029336A GB 8029336 A GB8029336 A GB 8029336A GB 2059958 A GB2059958 A GB 2059958A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
methanol
deoxy
compound
benzyloxycarbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB8029336A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of GB2059958A publication Critical patent/GB2059958A/en
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB8029336A 1979-09-26 1980-09-11 Fortimicin a and b and derivatives Withdrawn GB2059958A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/079,145 US4250304A (en) 1979-09-26 1979-09-26 2-Deoxy-2-substituted fortimicin A and B and derivatives

Publications (1)

Publication Number Publication Date
GB2059958A true GB2059958A (en) 1981-04-29

Family

ID=22148726

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8029336A Withdrawn GB2059958A (en) 1979-09-26 1980-09-11 Fortimicin a and b and derivatives

Country Status (10)

Country Link
US (1) US4250304A (enExample)
JP (1) JPS5657799A (enExample)
AR (1) AR226437A1 (enExample)
AU (1) AU6199180A (enExample)
BE (1) BE885402A (enExample)
DE (1) DE3036185A1 (enExample)
ES (1) ES8200119A1 (enExample)
FR (1) FR2465743A1 (enExample)
GB (1) GB2059958A (enExample)
GR (1) GR70198B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5659792A (en) * 1979-10-23 1981-05-23 Kyowa Hakko Kogyo Co Ltd Fortimicin derivative and its preparation
JPS5721399A (en) * 1980-07-12 1982-02-04 Kyowa Hakko Kogyo Co Ltd Fortimicin a derivative and its preparation
JPS5740496A (en) * 1980-08-22 1982-03-06 Microbial Chem Res Found Low toxic derivative of istamycin antibiotic
JPS58128395A (ja) * 1982-01-27 1983-07-30 Microbial Chem Res Found ３−０−デメチルイスタマイシンｂの低毒性誘導体
GB2118179A (en) * 1982-04-09 1983-10-26 Abbott Lab 2-Deoxy-3- demethoxyfortimicin A and B and related compounds
JPS6042394A (ja) * 1983-08-18 1985-03-06 Kowa Co 新規なアミノグリコシド及びその製法
US7794713B2 (en) * 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US20080213274A1 (en) * 2005-10-28 2008-09-04 Sabbadini Roger A Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
US20090074720A1 (en) * 2005-10-28 2009-03-19 Sabbadini Roger A Methods for decreasing immune response and treating immune conditions
US7862812B2 (en) * 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4192867A (en) * 1977-12-21 1980-03-11 Abbott Laboratories 2-Deoxyfortimicin A, 4-N-alkyl and 4-N-acyl-2-deoxyfortimicin B derivatives
US4169198A (en) * 1977-12-21 1979-09-25 Abbott Laboratories 2-Deoxyfortimicin B
US4176178A (en) * 1977-12-21 1979-11-27 Abbott Laboratories 2-Deoxy-2'-N-acyl and alkyl fortimicins A and B

Also Published As

Publication number Publication date
ES495313A0 (es) 1981-10-16
BE885402A (fr) 1981-03-25
FR2465743B1 (enExample) 1983-07-08
US4250304A (en) 1981-02-10
ES8200119A1 (es) 1981-10-16
GR70198B (enExample) 1982-08-31
AR226437A1 (es) 1982-07-15
JPS5657799A (en) 1981-05-20
AU6199180A (en) 1981-04-02
FR2465743A1 (fr) 1981-03-27
DE3036185A1 (de) 1981-04-16

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)