GB201902419D0 - Treatment of kidney injury - Google Patents

Treatment of kidney injury

Info

Publication number
GB201902419D0
GB201902419D0 GBGB1902419.9A GB201902419A GB201902419D0 GB 201902419 D0 GB201902419 D0 GB 201902419D0 GB 201902419 A GB201902419 A GB 201902419A GB 201902419 D0 GB201902419 D0 GB 201902419D0
Authority
GB
United Kingdom
Prior art keywords
treatment
kidney injury
kidney
injury
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1902419.9A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National University of Singapore
Singapore Health Services Pte Ltd
Original Assignee
National University of Singapore
Singapore Health Services Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National University of Singapore, Singapore Health Services Pte Ltd filed Critical National University of Singapore
Priority to GBGB1902419.9A priority Critical patent/GB201902419D0/en
Publication of GB201902419D0 publication Critical patent/GB201902419D0/en
Priority to PCT/EP2020/054580 priority patent/WO2020169783A1/en
Priority to CA3130027A priority patent/CA3130027A1/en
Priority to EA202191988A priority patent/EA202191988A1/ru
Priority to MX2021010025A priority patent/MX2021010025A/es
Priority to US16/798,101 priority patent/US11339216B2/en
Priority to CN202080016183.XA priority patent/CN113748131A/zh
Priority to TW109105725A priority patent/TWI874359B/zh
Priority to PH1/2021/552024A priority patent/PH12021552024A1/en
Priority to KR1020217030110A priority patent/KR20210144708A/ko
Priority to BR112021016613A priority patent/BR112021016613A2/pt
Priority to AU2020224346A priority patent/AU2020224346A1/en
Priority to TW114105926A priority patent/TWI923323B/zh
Priority to EP20707590.4A priority patent/EP3927742A1/en
Priority to JP2021549211A priority patent/JP7638215B2/ja
Priority to CL2021002212A priority patent/CL2021002212A1/es
Priority to US17/751,117 priority patent/US12234284B2/en
Priority to US19/028,642 priority patent/US20250270310A1/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GBGB1902419.9A 2019-02-22 2019-02-22 Treatment of kidney injury Ceased GB201902419D0 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
GBGB1902419.9A GB201902419D0 (en) 2019-02-22 2019-02-22 Treatment of kidney injury
JP2021549211A JP7638215B2 (ja) 2019-02-22 2020-02-21 腎障害の治療
PH1/2021/552024A PH12021552024A1 (en) 2019-02-22 2020-02-21 Treatment of kidney injury
BR112021016613A BR112021016613A2 (pt) 2019-02-22 2020-02-21 Agente capaz de inibir a sinalização mediada por interleucina 11 (il-11), uso deste na fabricação de um medicamento e métodos
EA202191988A EA202191988A1 (ru) 2019-02-22 2020-02-21 Лечение поражения почек
MX2021010025A MX2021010025A (es) 2019-02-22 2020-02-21 Tratamiento de lesión renal.
US16/798,101 US11339216B2 (en) 2019-02-22 2020-02-21 Treatment of kidney injury
CN202080016183.XA CN113748131A (zh) 2019-02-22 2020-02-21 肾损伤的治疗
TW109105725A TWI874359B (zh) 2019-02-22 2020-02-21 腎損傷之治療
PCT/EP2020/054580 WO2020169783A1 (en) 2019-02-22 2020-02-21 Treatment of kidney injury
KR1020217030110A KR20210144708A (ko) 2019-02-22 2020-02-21 신장 손상의 치료
CA3130027A CA3130027A1 (en) 2019-02-22 2020-02-21 Treatment of kidney injury
AU2020224346A AU2020224346A1 (en) 2019-02-22 2020-02-21 Treatment of kidney injury
TW114105926A TWI923323B (zh) 2019-02-22 2020-02-21 腎損傷之治療
EP20707590.4A EP3927742A1 (en) 2019-02-22 2020-02-21 Treatment of kidney injury
CL2021002212A CL2021002212A1 (es) 2019-02-22 2021-08-19 Tratamiento de lesión renal
US17/751,117 US12234284B2 (en) 2019-02-22 2022-05-23 Treatment of kidney injury
US19/028,642 US20250270310A1 (en) 2019-02-22 2025-01-17 Treatment of kidney injury

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1902419.9A GB201902419D0 (en) 2019-02-22 2019-02-22 Treatment of kidney injury

Publications (1)

Publication Number Publication Date
GB201902419D0 true GB201902419D0 (en) 2019-04-10

Family

ID=65998854

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1902419.9A Ceased GB201902419D0 (en) 2019-02-22 2019-02-22 Treatment of kidney injury

Country Status (15)

Country Link
US (3) US11339216B2 (https=)
EP (1) EP3927742A1 (https=)
JP (1) JP7638215B2 (https=)
KR (1) KR20210144708A (https=)
CN (1) CN113748131A (https=)
AU (1) AU2020224346A1 (https=)
BR (1) BR112021016613A2 (https=)
CA (1) CA3130027A1 (https=)
CL (1) CL2021002212A1 (https=)
EA (1) EA202191988A1 (https=)
GB (1) GB201902419D0 (https=)
MX (1) MX2021010025A (https=)
PH (1) PH12021552024A1 (https=)
TW (1) TWI874359B (https=)
WO (1) WO2020169783A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201902419D0 (en) 2019-02-22 2019-04-10 Singapore Health Serv Pte Ltd Treatment of kidney injury
TWI907583B (zh) * 2020-12-11 2025-12-11 大陸商江蘇恒瑞醫藥股份有限公司 Jak抑制劑在腎臟疾病中的應用
WO2023023473A1 (en) * 2021-08-16 2023-02-23 Sierra Oncology, Inc. Methods of using momelotinib to treat chronic kidney disease
CN115068442A (zh) * 2021-09-13 2022-09-20 荣灿生物医药技术(上海)有限公司 核酸的纳米颗粒组合物、其制备方法和用途
CN113960302B (zh) * 2021-09-29 2024-04-23 中国人民解放军军事科学院军事医学研究院 一种基于高内涵技术的肾毒性检测方法及其应用
US20230145258A1 (en) * 2021-11-11 2023-05-11 Laboratory Corporation Of America Holdings Predicting a Diagnostic Test Result From Patient Laboratory Testing History
US20250082608A1 (en) * 2021-12-16 2025-03-13 Singapore Health Services Pte Ltd. Treatment and prevention of glomerular disease
CN114982708A (zh) * 2022-05-11 2022-09-02 成都医学院第一附属医院 一种小鼠造影剂肾病模型及其构建方法
CN119233818A (zh) 2022-05-20 2024-12-31 学校法人藤田学园 用于肾损伤的治疗方法或预防方法中的药物组合物和包含该药物组合物的联用药、以及ccbl1抑制剂
GB202218388D0 (en) 2022-12-07 2023-01-18 Vvb Bio Pte Ltd GP130 antigen-binding molecules
CN120787238A (zh) 2023-01-06 2025-10-14 拉森医疗公司 用于治疗甲状腺眼病的抗IL-11Rα抗体
CN119925593B (zh) * 2023-06-05 2025-11-25 北京东方百泰生物科技股份有限公司 一种抗il-11单克隆抗体的药物制剂
GB202311050D0 (en) 2023-07-19 2023-08-30 Vvb Bio Pte Ltd GP130 antigen-binding molecules
GB202405551D0 (en) 2024-04-19 2024-06-05 Vvb Bio Pte Ltd Combination treatment
WO2025238135A2 (en) 2024-05-17 2025-11-20 UCB Biopharma SRL Antibody with binding specificity for il-11
GB202408044D0 (en) 2024-06-06 2024-07-24 Vvb Bio Pte Ltd gp130 antigen-binding molecules
CN119548507A (zh) * 2024-11-12 2025-03-04 安徽医科大学 5-甲基四氢叶酸在制备治疗肾脏纤维化的药物中的应用

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ES2259800T3 (es) 1990-06-11 2006-10-16 Gilead Sciences, Inc. Procedimientos de uso de ligandos de acido nucleico.
ES2093562B1 (es) 1995-05-26 1997-07-01 Univ Santiago Compostela Estabilizacion de sistemas coloidales mediante formacion de complejos ionicos lipido-polisacarido.
US6649192B2 (en) 1996-07-29 2003-11-18 Universidade De Santiago De Compostela Application of nanoparticles based on hydrophilic polymers as pharmaceutical forms
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
CA2237915A1 (en) 1998-05-19 1999-11-19 Stephen Shaughnessy Osteoporosis treatment
HK1047109A1 (zh) 1999-10-15 2003-02-07 University Of Massachusetts 作为指定基因干预工具的rna干预轨迹基因
MX352516B (es) 2006-07-05 2017-04-06 Fibrotech Therapeutics Pty Ltd Compuestos terapeuticos.
US8182814B2 (en) 2007-10-26 2012-05-22 Csl Limited Methods of treating inflammatory airway conditions by inhibition of IL-11 activity
JP5330398B2 (ja) 2007-10-26 2013-10-30 シーエスエル、リミテッド サイトカインムテイン
US8518888B2 (en) 2008-10-14 2013-08-27 Csl Limited Method of treatment of gastrointestinal-type cancer with antagonistic antibodies to IL-11R
CN117843785A (zh) 2013-02-07 2024-04-09 Csl有限公司 Il-11r结合蛋白及其应用
GB201522186D0 (en) * 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
CN108210909A (zh) * 2016-12-15 2018-06-29 深圳瑞健生命科学研究院有限公司 预防和治疗脂质肾损伤的药物及其用途
CN108210894A (zh) * 2016-12-15 2018-06-29 深圳瑞健生命科学研究院有限公司 预防和治疗病理性肾组织损伤的药物及其用途
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GB201621431D0 (en) 2016-12-16 2017-02-01 Singapore Health Services Pte Ltd And Nat Univ Of Singapore The Decoy cytokine receptor
GB201621439D0 (en) 2016-12-16 2017-02-01 Singapore Health Services Pte Ltd And Nat Univ Of Singapore IL-11Ra Antibodies
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GB201809699D0 (en) 2018-06-13 2018-08-01 Singapore Health Serv Pte Ltd IL-11 antibodies
GB201902419D0 (en) 2019-02-22 2019-04-10 Singapore Health Serv Pte Ltd Treatment of kidney injury

Also Published As

Publication number Publication date
AU2020224346A1 (en) 2021-10-07
US20250270310A1 (en) 2025-08-28
CA3130027A1 (en) 2020-08-27
US11339216B2 (en) 2022-05-24
JP2022521591A (ja) 2022-04-11
KR20210144708A (ko) 2021-11-30
CN113748131A (zh) 2021-12-03
BR112021016613A2 (pt) 2021-11-03
TWI874359B (zh) 2025-03-01
TW202037605A (zh) 2020-10-16
US12234284B2 (en) 2025-02-25
MX2021010025A (es) 2021-11-12
EP3927742A1 (en) 2021-12-29
EA202191988A1 (ru) 2021-12-08
US20200270340A1 (en) 2020-08-27
US20220403017A1 (en) 2022-12-22
PH12021552024A1 (en) 2022-08-22
TW202521575A (zh) 2025-06-01
CL2021002212A1 (es) 2022-04-18
WO2020169783A1 (en) 2020-08-27
JP7638215B2 (ja) 2025-03-03

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)