GB201809699D0 - IL-11 antibodies - Google Patents

IL-11 antibodies

Info

Publication number
GB201809699D0
GB201809699D0 GBGB1809699.0A GB201809699A GB201809699D0 GB 201809699 D0 GB201809699 D0 GB 201809699D0 GB 201809699 A GB201809699 A GB 201809699A GB 201809699 D0 GB201809699 D0 GB 201809699D0
Authority
GB
United Kingdom
Prior art keywords
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1809699.0A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enleofen Bio Pte Ltd
National University of Singapore
Singapore Health Services Pte Ltd
Original Assignee
Enleofen Bio Pte Ltd
National University of Singapore
Singapore Health Services Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enleofen Bio Pte Ltd, National University of Singapore, Singapore Health Services Pte Ltd filed Critical Enleofen Bio Pte Ltd
Priority to GBGB1809699.0A priority Critical patent/GB201809699D0/en
Publication of GB201809699D0 publication Critical patent/GB201809699D0/en
Priority to US16/440,840 priority patent/US11084874B2/en
Priority to AU2019286795A priority patent/AU2019286795B2/en
Priority to CN201980054506.1A priority patent/CN113056481A/zh
Priority to BR112020025443-6A priority patent/BR112020025443A2/pt
Priority to PCT/EP2019/065598 priority patent/WO2019238882A1/en
Priority to JP2020568955A priority patent/JP2021535733A/ja
Priority to KR1020217000825A priority patent/KR20210031690A/ko
Priority to JOP/2020/0309A priority patent/JOP20200309A1/ar
Priority to PE2020001992A priority patent/PE20211498A1/es
Priority to CA3102483A priority patent/CA3102483A1/en
Priority to CR20210009A priority patent/CR20210009A/es
Priority to MX2020013583A priority patent/MX2020013583A/es
Priority to TW108120516A priority patent/TWI924625B/zh
Priority to MA052884A priority patent/MA52884A/fr
Priority to EP19734285.0A priority patent/EP3807314A1/en
Priority to SG11202011782XA priority patent/SG11202011782XA/en
Priority to EA202092668A priority patent/EA202092668A1/ru
Priority to CONC2020/0015383A priority patent/CO2020015383A2/es
Priority to IL279356A priority patent/IL279356A/en
Priority to CL2020003223A priority patent/CL2020003223A1/es
Priority to DO2020000245A priority patent/DOP2020000245A/es
Priority to SA520420801A priority patent/SA520420801B1/ar
Priority to PH12020552232A priority patent/PH12020552232A1/en
Priority to ECSENADI2021695A priority patent/ECSP21000695A/es
Priority to US17/212,456 priority patent/US20210230266A1/en
Priority to US18/592,665 priority patent/US20240190953A1/en
Priority to US18/592,746 priority patent/US20240270837A1/en
Priority to JP2024076402A priority patent/JP2024105466A/ja
Priority to DO2024000220A priority patent/DOP2024000220A/es
Priority to AU2026201704A priority patent/AU2026201704A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hospice & Palliative Care (AREA)
GBGB1809699.0A 2018-06-13 2018-06-13 IL-11 antibodies Ceased GB201809699D0 (en)

Priority Applications (31)

Application Number Priority Date Filing Date Title
GBGB1809699.0A GB201809699D0 (en) 2018-06-13 2018-06-13 IL-11 antibodies
EA202092668A EA202092668A1 (ru) 2018-06-13 2019-06-13 Антитела к ил-11
MA052884A MA52884A (fr) 2018-06-13 2019-06-13 Anticorps anti-il-11
EP19734285.0A EP3807314A1 (en) 2018-06-13 2019-06-13 Il-11 antibodies
CN201980054506.1A CN113056481A (zh) 2018-06-13 2019-06-13 Il-11抗体
BR112020025443-6A BR112020025443A2 (pt) 2018-06-13 2019-06-13 Anticorpos il-11
PCT/EP2019/065598 WO2019238882A1 (en) 2018-06-13 2019-06-13 Il-11 antibodies
JP2020568955A JP2021535733A (ja) 2018-06-13 2019-06-13 Ｉｌ−１１抗体
KR1020217000825A KR20210031690A (ko) 2018-06-13 2019-06-13 Il-11 항체
JOP/2020/0309A JOP20200309A1 (ar) 2018-06-13 2019-06-13 أجسام مضادة لـ il-11
PE2020001992A PE20211498A1 (es) 2018-06-13 2019-06-13 Anticuerpos dirigidos contra il-11
AU2019286795A AU2019286795B2 (en) 2018-06-13 2019-06-13 IL-11 antibodies
CR20210009A CR20210009A (es) 2018-06-13 2019-06-13 Anticuerpos dirigidos contra il-11
MX2020013583A MX2020013583A (es) 2018-06-13 2019-06-13 Anticuerpos il-11.
TW108120516A TWI924625B (zh) 2018-06-13 2019-06-13 Il-11抗體
US16/440,840 US11084874B2 (en) 2018-06-13 2019-06-13 IL-11 antibodies
SG11202011782XA SG11202011782XA (en) 2018-06-13 2019-06-13 Il-11 antibodies
CA3102483A CA3102483A1 (en) 2018-06-13 2019-06-13 Il-11 antibodies
CONC2020/0015383A CO2020015383A2 (es) 2018-06-13 2020-12-09 Anticuerpos dirigidos contra il-11
IL279356A IL279356A (en) 2018-06-13 2020-12-10 IL-11 antibodies
CL2020003223A CL2020003223A1 (es) 2018-06-13 2020-12-11 Anticuerpos il-11
DO2020000245A DOP2020000245A (es) 2018-06-13 2020-12-11 Anticuerpos il-11
SA520420801A SA520420801B1 (ar) 2018-06-13 2020-12-13 أil جسام مضادة لـ -11
PH12020552232A PH12020552232A1 (en) 2018-06-13 2020-12-13 IL-11 Antibodies
ECSENADI2021695A ECSP21000695A (es) 2018-06-13 2021-01-06 Anticuerpos dirigidos contra il-11
US17/212,456 US20210230266A1 (en) 2018-06-13 2021-03-25 Il-11 antibodies
US18/592,665 US20240190953A1 (en) 2018-06-13 2024-03-01 Il-11 antibodies
US18/592,746 US20240270837A1 (en) 2018-06-13 2024-03-01 Il-11 antibodies
JP2024076402A JP2024105466A (ja) 2018-06-13 2024-05-09 Ｉｌ－１１抗体
DO2024000220A DOP2024000220A (es) 2018-06-13 2024-10-29 Anticuerpos il-11
AU2026201704A AU2026201704A1 (en) 2018-06-13 2026-03-05 IL-11 antibodies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1809699.0A GB201809699D0 (en) 2018-06-13 2018-06-13 IL-11 antibodies

Publications (1)

Publication Number Publication Date
GB201809699D0 true GB201809699D0 (en) 2018-08-01

Family

ID=63042160

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1809699.0A Ceased GB201809699D0 (en) 2018-06-13 2018-06-13 IL-11 antibodies

Country Status (24)

Country Link
US (4) US11084874B2 (OSRAM)
EP (1) EP3807314A1 (OSRAM)
JP (2) JP2021535733A (OSRAM)
KR (1) KR20210031690A (OSRAM)
CN (1) CN113056481A (OSRAM)
AU (2) AU2019286795B2 (OSRAM)
BR (1) BR112020025443A2 (OSRAM)
CA (1) CA3102483A1 (OSRAM)
CL (1) CL2020003223A1 (OSRAM)
CO (1) CO2020015383A2 (OSRAM)
CR (1) CR20210009A (OSRAM)
DO (2) DOP2020000245A (OSRAM)
EA (1) EA202092668A1 (OSRAM)
EC (1) ECSP21000695A (OSRAM)
GB (1) GB201809699D0 (OSRAM)
IL (1) IL279356A (OSRAM)
JO (1) JOP20200309A1 (OSRAM)
MA (1) MA52884A (OSRAM)
MX (1) MX2020013583A (OSRAM)
PE (1) PE20211498A1 (OSRAM)
PH (1) PH12020552232A1 (OSRAM)
SA (1) SA520420801B1 (OSRAM)
SG (1) SG11202011782XA (OSRAM)
WO (1) WO2019238882A1 (OSRAM)

Families Citing this family (32)

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Publication number Priority date Publication date Assignee Title
GB201522186D0 (en) 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
CA3045871A1 (en) 2016-12-16 2018-06-21 Singapore Health Services Pte Ltd Il-11 antibodies
GB201621439D0 (en) 2016-12-16 2017-02-01 Singapore Health Services Pte Ltd And Nat Univ Of Singapore IL-11Ra Antibodies
US20200087390A1 (en) 2016-12-21 2020-03-19 Amgen Inc. Anti-tnf alpha antibody formulations
GB201716733D0 (en) * 2017-10-12 2017-11-29 Nat Univ Singapore Treatment of SMC mediated disease
AU2020211695A1 (en) * 2019-01-21 2021-09-02 National University Of Singapore Treatment of hepatotoxicity
GB201902419D0 (en) 2019-02-22 2019-04-10 Singapore Health Serv Pte Ltd Treatment of kidney injury
CN114364693A (zh) 2019-05-03 2022-04-15 新加坡保健服务私人有限公司 代谢性疾病的治疗和预防
GB202009292D0 (en) 2020-06-18 2020-08-05 Singapore Health Serv Pte Ltd Treatment and prevention of disease caused by type IV collagen dysfunction
US20230235029A1 (en) * 2020-07-20 2023-07-27 Integrated Biotherapeutics, Inc. Broadly neutralizing binding molecules against marburgviruses
CN113651888B (zh) * 2020-08-13 2022-08-16 广东东阳光药业有限公司 Il-11的抗体及其应用
GB202017244D0 (en) 2020-10-30 2020-12-16 Nat Univ Singapore Methods to extend health-span and treat age-related diseases
CN114681592A (zh) * 2020-12-31 2022-07-01 天境生物科技(杭州)有限公司 包含可溶性gp130二聚体的制剂和使用方法
CN113980129B (zh) * 2021-01-15 2023-07-28 东大生物技术(苏州)有限公司 一组il-11单克隆抗体及其医药用途
CA3211686A1 (en) 2021-02-26 2022-09-01 Bayer Aktiengesellschaft Inhibitors of il-11 or il-11ra for use in the treatment of abnormal uterine bleeding
JP2024526944A (ja) 2021-07-26 2024-07-19 ベーリンガー・インゲルハイム・インターナショナル・ゲーエムベーハー アルコール性肝疾患の処置および予防
CN115975027B (zh) * 2021-08-12 2023-10-20 广东东阳光药业股份有限公司 Il-11人源化抗体及其应用
WO2023034809A1 (en) 2021-08-30 2023-03-09 Lassen Therapeutics 1, Inc. Anti-il-11rα antibodies
EP4448096A1 (en) 2021-12-16 2024-10-23 Singapore Health Services Pte. Ltd. Treatment and prevention of glomerular disease
WO2023143556A1 (zh) * 2022-01-29 2023-08-03 迈威(上海)生物科技股份有限公司 一种抗白介素-11的抗体及其应用
GB202218388D0 (en) 2022-12-07 2023-01-18 Vvb Bio Pte Ltd GP130 antigen-binding molecules
WO2024146458A1 (zh) 2023-01-06 2024-07-11 广东东阳光药业股份有限公司 抗il-11细胞因子人源化抗体
WO2024225979A1 (en) 2023-04-25 2024-10-31 Vvb Bio Pte Ltd Anti il-11 antibody
CN120518762B (zh) * 2023-06-05 2025-12-26 北京东方百泰生物科技股份有限公司 一种结合il-11的抗体、其抗原结合片段及应用
GB202311050D0 (en) 2023-07-19 2023-08-30 Vvb Bio Pte Ltd GP130 antigen-binding molecules
IL326237A (en) * 2023-07-28 2026-03-01 Mabwell Shanghai Bioscience Co Ltd Use of anti-interleukin-11 antibody in the preparation of a drug for the treatment of tumors
WO2025108343A1 (zh) * 2023-11-22 2025-05-30 上海华奥泰生物药业股份有限公司 靶向il-11的抗原结合蛋白
WO2025146029A1 (zh) * 2024-01-02 2025-07-10 上海华奥泰生物药业股份有限公司 靶向il-11和tslp的多特异性分子
GB202405551D0 (en) 2024-04-19 2024-06-05 Vvb Bio Pte Ltd Combination treatment
GB202408044D0 (en) 2024-06-06 2024-07-24 Vvb Bio Pte Ltd gp130 antigen-binding molecules
WO2026001793A1 (zh) * 2024-06-27 2026-01-02 上海华奥泰生物药业股份有限公司 靶向il-11的抗原结合蛋白及其用途
CN119119262B (zh) * 2024-08-02 2025-05-02 杭州曼迪生物科技有限公司 一种干细胞冻干粉及其在制备药物或者化妆品中的用途

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
PL356836A1 (en) * 2000-02-10 2004-07-12 Abbott Laboratories Antibodies that bind human interleukin-18 and methods of making and using
US8518888B2 (en) * 2008-10-14 2013-08-27 Csl Limited Method of treatment of gastrointestinal-type cancer with antagonistic antibodies to IL-11R
GB201522186D0 (en) * 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
RU2016125115A (ru) * 2016-06-23 2017-12-28 Федеральное государственное бюджетное учреждение науки Институт биологического приборостроения с опытным производством Российской Академии наук (ИБП РАН) Терапевтическое антитело, специфичное к интерлейкину-11, ингибирующее сигналирование через его рецептор, и способ его использования для лечения пациентов
CA3045871A1 (en) * 2016-12-16 2018-06-21 Singapore Health Services Pte Ltd Il-11 antibodies
RU2016151730A (ru) * 2016-12-28 2018-06-29 Федеральное государственное бюджетное учреждение науки Институт биологического приборостроения с опытным производством Российской Академии наук (ИБП РАН) Антитела для лабораторной диагностики концентрации интерлейкина-11

Also Published As

Publication number Publication date
TW202003560A (zh) 2020-01-16
EA202092668A1 (ru) 2021-05-18
US20210230266A1 (en) 2021-07-29
JOP20200309A1 (ar) 2020-11-30
US20240270837A1 (en) 2024-08-15
SG11202011782XA (en) 2020-12-30
CO2020015383A2 (es) 2021-04-19
MA52884A (fr) 2021-04-21
US20240190953A1 (en) 2024-06-13
MX2020013583A (es) 2021-04-13
CN113056481A (zh) 2021-06-29
AU2019286795B2 (en) 2026-03-12
CR20210009A (es) 2021-06-21
CA3102483A1 (en) 2019-12-19
US11084874B2 (en) 2021-08-10
WO2019238882A1 (en) 2019-12-19
DOP2024000220A (es) 2025-02-28
IL279356A (en) 2021-01-31
BR112020025443A2 (pt) 2021-03-16
PH12020552232A1 (en) 2021-06-28
AU2026201704A1 (en) 2026-03-26
DOP2020000245A (es) 2021-10-31
JP2024105466A (ja) 2024-08-06
EP3807314A1 (en) 2021-04-21
KR20210031690A (ko) 2021-03-22
ECSP21000695A (es) 2021-03-31
PE20211498A1 (es) 2021-08-11
CL2020003223A1 (es) 2021-07-30
SA520420801B1 (ar) 2023-12-07
AU2019286795A1 (en) 2021-01-28
US20200031918A1 (en) 2020-01-30
JP2021535733A (ja) 2021-12-23

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)