GB2002349A - Prostane derivatives - Google Patents

Prostane derivatives

Info

Publication number
GB2002349A
GB2002349A GB7828887A GB7828887A GB2002349A GB 2002349 A GB2002349 A GB 2002349A GB 7828887 A GB7828887 A GB 7828887A GB 7828887 A GB7828887 A GB 7828887A GB 2002349 A GB2002349 A GB 2002349A
Authority
GB
United Kingdom
Prior art keywords
image
prostane derivatives
trans
alpha
prostane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7828887A
Other versions
GB2002349B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Priority to GB7828887A priority Critical patent/GB2002349B/en
Publication of GB2002349A publication Critical patent/GB2002349A/en
Application granted granted Critical
Publication of GB2002349B publication Critical patent/GB2002349B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The derivative have the formula I <IMAGE> for example 1-acetoxy-16-(3- chlorophenoxy)-17,18,19,20- tetranor-4-cis, 13-trans-prostadien- 9 alpha ,11 alpha , 15-triol, wherein <IMAGE> represents <IMAGE> and X is an ethylene or trans-vinylene radical and possess high luteolytic activity.
GB7828887A 1977-08-12 1978-07-05 Prostane derivatives Expired GB2002349B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7828887A GB2002349B (en) 1977-08-12 1978-07-05 Prostane derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3392077 1977-08-12
GB7828887A GB2002349B (en) 1977-08-12 1978-07-05 Prostane derivatives

Publications (2)

Publication Number Publication Date
GB2002349A true GB2002349A (en) 1979-02-21
GB2002349B GB2002349B (en) 1982-05-19

Family

ID=26262085

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7828887A Expired GB2002349B (en) 1977-08-12 1978-07-05 Prostane derivatives

Country Status (1)

Country Link
GB (1) GB2002349B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0171441A1 (en) * 1984-08-10 1986-02-19 Ono Pharmaceutical Co., Ltd. Prostaglandin analogues, processes for their preparation and compositions containing them

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0171441A1 (en) * 1984-08-10 1986-02-19 Ono Pharmaceutical Co., Ltd. Prostaglandin analogues, processes for their preparation and compositions containing them

Also Published As

Publication number Publication date
GB2002349B (en) 1982-05-19

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee