GB2001059A - Pharmaceutical derivatives of amines and amino acids - Google Patents

Pharmaceutical derivatives of amines and amino acids

Info

Publication number
GB2001059A
GB2001059A GB7827972A GB7827972A GB2001059A GB 2001059 A GB2001059 A GB 2001059A GB 7827972 A GB7827972 A GB 7827972A GB 7827972 A GB7827972 A GB 7827972A GB 2001059 A GB2001059 A GB 2001059A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
carbon atoms
amines
amino acids
cnh2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7827972A
Other versions
GB2001059B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merrell Toraude et Cie
Original Assignee
Merrell Toraude et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude et Cie filed Critical Merrell Toraude et Cie
Publication of GB2001059A publication Critical patent/GB2001059A/en
Application granted granted Critical
Publication of GB2001059B publication Critical patent/GB2001059B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The compounds have the formula RaHN-A-CH=CH-CR1R2 -NHRb wherein A is -CH2-,-(CH2)2- or -CH(CH3)-; R1 is -CH=CH2 or -C=CH; R2 is hydrogen or COR wherein R is hydroxy, alkoxy or 1 to 8 carbon atoms, -NR4R5 wherein R4 and R5 are the same or different and are each hydrogen or alkyl of 1 to 4 carbon atoms, or -NH- CHR6-COOH wherein R6 is hydrogen, alkyl of 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl, Ra and Rb are the same or different and are each hydrogen, HN=CNH2-, (C1-4alkyl)carbonyl, (C1-4alkoxy)carbonyl or -CO-CHNH2- R7 wherein R7 is hydrogen, alkyl of 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; with the provisos that Rb is not HN=CNH2-; that when R2 is hydrogen, R1 is -C=CH; that when A is -CH(CH3)-, R2 is hydrogen; and that when Ra is HN=CNH2, A is methylene.
GB7827972A 1977-07-01 1978-06-27 Derivatives of amines and amino acids Expired GB2001059B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81211577A 1977-07-01 1977-07-01

Publications (2)

Publication Number Publication Date
GB2001059A true GB2001059A (en) 1979-01-24
GB2001059B GB2001059B (en) 1982-04-21

Family

ID=25208552

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7827972A Expired GB2001059B (en) 1977-07-01 1978-06-27 Derivatives of amines and amino acids

Country Status (7)

Country Link
JP (1) JPS5481205A (en)
BE (1) BE868591A (en)
CA (1) CA1121375A (en)
DE (1) DE2827759A1 (en)
FR (1) FR2395982A1 (en)
GB (1) GB2001059B (en)
ZA (1) ZA783274B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2484255A1 (en) * 1980-06-16 1981-12-18 Merrell Dow Pharma NEW VETERINARY DRUGS FOR INHIBITING THE DEVELOPMENT OF PROTOZOA AND THERAPEUTIC COMPOSITIONS AND PHARMACEUTICAL FORMS CONTAINING THESE MEDICAMENTS
EP0341624A2 (en) * 1988-05-13 1989-11-15 Merrell Dow Pharmaceuticals Inc. Method of effecting immunosuppression

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4437873A (en) 1981-03-23 1984-03-20 Merrell Dow Pharmaceuticals Inc. Method of inhibiting algae
DE3207787A1 (en) * 1982-03-04 1983-09-08 Robert Bosch Gmbh, 7000 Stuttgart FUEL FEEDING SYSTEM FOR AN INTERNAL COMBUSTION ENGINE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2766285A (en) * 1952-10-20 1956-10-09 Lilly Co Eli Substituted aminopropynes and process for their preparation
US3079345A (en) * 1959-04-30 1963-02-26 Dow Chemical Co Propargyl compounds as corrosion inhibitors
US3960927A (en) * 1975-03-18 1976-06-01 Richardson-Merrell Inc. Olefinic derivatives of amino acids
US3959356A (en) * 1975-03-18 1976-05-25 Richardson-Merrell Inc. Acetylene derivatives of amino acids

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2484255A1 (en) * 1980-06-16 1981-12-18 Merrell Dow Pharma NEW VETERINARY DRUGS FOR INHIBITING THE DEVELOPMENT OF PROTOZOA AND THERAPEUTIC COMPOSITIONS AND PHARMACEUTICAL FORMS CONTAINING THESE MEDICAMENTS
EP0341624A2 (en) * 1988-05-13 1989-11-15 Merrell Dow Pharmaceuticals Inc. Method of effecting immunosuppression
EP0341624A3 (en) * 1988-05-13 1991-06-05 Merrell Dow Pharmaceuticals Inc. Method of effecting immunosuppression

Also Published As

Publication number Publication date
DE2827759A1 (en) 1979-01-25
JPS635384B2 (en) 1988-02-03
CA1121375A (en) 1982-04-06
JPS5481205A (en) 1979-06-28
FR2395982A1 (en) 1979-01-26
ZA783274B (en) 1979-06-27
BE868591A (en) 1978-10-16
GB2001059B (en) 1982-04-21
FR2395982B1 (en) 1980-07-18

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19940627