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Richard Wolffenstein
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Organic Low-Molecular-Weight Compounds And Preparation Thereof
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Abstract
5811. Wolffenstein, R. March 8. Esters of polyhalogen-substituted alcohols are obtained by directly heating the alcohols with therapeutically active acids having an unsubstituted phenolic group, or no phenolic group, or with the chlorides of such acids In this manner are produced the salicylic esters of trichlorbutyl alcohol and trichlorisopropyl alcohol, the p-cresotinic ester of acetonechloroform, the isovaleric ester of tribromisobutyl alcohol, and the bromisovaleric ester of tribromisobutyl alcohol. The polyhalogen alcohols used are preferably those having the halogen atoms attached to one carbon atom. The products are useful in therapeutics. Salicylchloride is obtained by the action of thionylchloride upon salicylic acid.
GB191305811D1913-03-081913-03-08Process for the Manufacture of Esters of Polyhalogen-substituted Alcohols with Therapeutically Active Acids.
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