GB1568981A - Cyclization of peptides - Google Patents

Cyclization of peptides Download PDF

Info

Publication number
GB1568981A
GB1568981A GB44382/76A GB4438276A GB1568981A GB 1568981 A GB1568981 A GB 1568981A GB 44382/76 A GB44382/76 A GB 44382/76A GB 4438276 A GB4438276 A GB 4438276A GB 1568981 A GB1568981 A GB 1568981A
Authority
GB
United Kingdom
Prior art keywords
peptide
boc
cys
cycle
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB44382/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Armour Pharmaceutical Co
Original Assignee
Armour Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Armour Pharmaceutical Co filed Critical Armour Pharmaceutical Co
Publication of GB1568981A publication Critical patent/GB1568981A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/15—Oxytocin or vasopressin; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB44382/76A 1975-11-12 1976-10-26 Cyclization of peptides Expired GB1568981A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/631,408 US4033940A (en) 1975-11-12 1975-11-12 Cyclization of peptides

Publications (1)

Publication Number Publication Date
GB1568981A true GB1568981A (en) 1980-06-11

Family

ID=24531072

Family Applications (1)

Application Number Title Priority Date Filing Date
GB44382/76A Expired GB1568981A (en) 1975-11-12 1976-10-26 Cyclization of peptides

Country Status (5)

Country Link
US (1) US4033940A (US20110009641A1-20110113-C00185.png)
JP (1) JPS5259179A (US20110009641A1-20110113-C00185.png)
DE (1) DE2647843A1 (US20110009641A1-20110113-C00185.png)
FR (1) FR2331553A1 (US20110009641A1-20110113-C00185.png)
GB (1) GB1568981A (US20110009641A1-20110113-C00185.png)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4216141A (en) * 1978-07-19 1980-08-05 The Salk Institute For Biological Studies Method for cyclization of peptides
US4212795A (en) * 1978-11-13 1980-07-15 Armour Pharmaceutical Company Cyclization of peptides
SE447263B (sv) * 1979-04-20 1986-11-03 Bonnierfoeretagen Ab Syntetisk, antigeniskt aktiv polypeptid och antigeniskt medel innehallande nemnda polypeptid
BR8207790A (pt) * 1981-07-15 1983-06-21 Kingdon Craig R Gene estrutural de poliproteina precursor da calcitonina humana
US4469632A (en) * 1982-09-24 1984-09-04 Armour Pharmaceutical Company D-Arginine24 calcitonin
US4444681A (en) * 1982-09-24 1984-04-24 Armour Pharmaceutical Company L-Tyrosine21 calcitonin
US4451395A (en) * 1982-11-08 1984-05-29 Armour Pharmaceutical Company Des-serine2 -des-tyrosine22 calcitonin
US4663309A (en) * 1983-06-29 1987-05-05 University Patents, Inc. Novel peptide hormones with calcitonin-like activity
US4528132A (en) * 1984-01-13 1985-07-09 Armour Pharmaceutical Company [16-Alanine]calcitonin
US4623716A (en) 1984-11-01 1986-11-18 Usv Pharmaceutical Corp. Process for the preparation and purification of peptides
JPS61112099A (ja) * 1984-11-06 1986-05-30 Mitsubishi Petrochem Co Ltd 新規ポリペプチド及びその製造法
US4604238A (en) * 1984-12-10 1986-08-05 Armour Pharmaceutical Company Analogs of calcitonin
US4820804A (en) * 1987-04-21 1989-04-11 Rorer Pharmaceutical Corporation Analogs of [1,7-di-alanine, des-19-leucine]calcitonin
US4824936A (en) * 1987-05-06 1989-04-25 Rorer Pharmaceutical Corporation (19-Alanine) calcitonin
US5674850A (en) * 1993-12-23 1997-10-07 Ferring Ab High purity desmopressin produced in large single batches
DE69427820T2 (de) * 1993-06-29 2001-11-08 Ferring B.V., Hoofdorp Zusammensetzungen zur nasalen verabreichung von desmopressin
US5500413A (en) * 1993-06-29 1996-03-19 Ferring Ab Process for manufacture of 1-deamino-8-D-arginine vasopressin
ES2149880T3 (es) * 1993-06-29 2000-11-16 Ferring Bv Sintesis de peptidos ciclicos.
US5482931A (en) * 1993-06-29 1996-01-09 Ferring Ab Stabilized pharmaceutical peptide compositions
SE9400918L (sv) * 1994-03-18 1995-09-19 Anne Fjellstad Paulsen Stabiliserad komposition för oral administrering av peptider
US5763398A (en) * 1996-06-20 1998-06-09 Ferring B.V. Nasal administration of desmopressin
US5922680A (en) * 1996-10-23 1999-07-13 Ferring, B.V. Stabilized composition for oral administration of peptides
AU2003227907A1 (en) * 2002-05-03 2003-11-17 Avecia Limited Process for the synthesis of peptides amides by side-chain attachement to a solid phase
US20120128684A1 (en) 2008-08-25 2012-05-24 Burnham Institute For Medical Research Conserved Hemagglutinin Epitope, Antibodies to the Epitope and Methods of Use
JP5693460B2 (ja) 2008-11-12 2015-04-01 セラクローン サイエンシーズ， インコーポレイテッド ヒトＭ２ｅペプチド免疫原
US9403876B2 (en) 2009-05-18 2016-08-02 Brown University Cyclic-GluR6 analogs, methods of treatment and use
HRP20211561T8 (hr) 2014-06-12 2022-03-04 Ra Pharmaceuticals, Inc. Modulacija aktivnosti komplementa
PT3250230T (pt) 2015-01-28 2021-12-07 Ra Pharmaceuticals Inc Moduladores da atividade do complemento
JP6525171B2 (ja) 2015-04-13 2019-06-05 国立研究開発法人産業技術総合研究所 環状化サイトカイン及びその製法
US10899796B2 (en) 2015-11-09 2021-01-26 Tufts Medical Center Compounds and methods for treating pain
WO2017105939A1 (en) 2015-12-16 2017-06-22 Ra Pharmaceuticals, Inc. Modulators of complement activity
BR112019011053A2 (pt) 2016-12-07 2019-10-15 Ra Pharmaceuticals Inc moduladores da atividade do complemento

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929758A (en) * 1974-09-12 1975-12-30 Armour Pharma Cyclization of cysteine-containing peptides

Also Published As

Publication number Publication date
FR2331553A1 (fr) 1977-06-10
FR2331553B1 (US20110009641A1-20110113-C00185.png) 1980-11-28
US4033940A (en) 1977-07-05
JPS5259179A (en) 1977-05-16
DE2647843A1 (de) 1977-05-26
JPS6140680B2 (US20110009641A1-20110113-C00185.png) 1986-09-10

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Publication Publication Date Title
GB1568981A (en) Cyclization of peptides
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US4537716A (en) Des-serine2 or des-glycine2 -leucine22 calcitonin
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US4659804A (en) (Bis-1,7-S-acetamidomethyl-L-cysteine)salmon calcitonin
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US5001222A (en) Des-17-histidine-calcitonin
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US4820804A (en) Analogs of [1,7-di-alanine, des-19-leucine]calcitonin
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US4764591A (en) Des-19-leucine, 20-glutamine, 21-threonine, 22-tyrosine-calcitonin
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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee