GB1568740A - 1,4-dihydro-2,6 dimenthyl - 4 - (3 - nitrophenyl) - 3,5-pyridinendicarboxylic acid ester several processes for its preparation and its use as a peripheral vasodilator - Google Patents
1,4-dihydro-2,6 dimenthyl - 4 - (3 - nitrophenyl) - 3,5-pyridinendicarboxylic acid ester several processes for its preparation and its use as a peripheral vasodilator Download PDFInfo
- Publication number
- GB1568740A GB1568740A GB44332/77A GB4433277A GB1568740A GB 1568740 A GB1568740 A GB 1568740A GB 44332/77 A GB44332/77 A GB 44332/77A GB 4433277 A GB4433277 A GB 4433277A GB 1568740 A GB1568740 A GB 1568740A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- ester
- acid isopropyl
- reacted
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2650013A DE2650013C3 (de) | 1976-10-30 | 1976-10-30 | 1.4-Dihydro-2.6-dimethyl-4-(3-nitrophenyl)-3.5-pyridindicarbonsäureisopropyl-(2-propoxy-äthyl)-ester, Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1568740A true GB1568740A (en) | 1980-06-04 |
Family
ID=5992142
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB44332/77A Expired GB1568740A (en) | 1976-10-30 | 1977-10-25 | 1,4-dihydro-2,6 dimenthyl - 4 - (3 - nitrophenyl) - 3,5-pyridinendicarboxylic acid ester several processes for its preparation and its use as a peripheral vasodilator |
Country Status (14)
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999001432A1 (ru) * | 1997-07-03 | 1999-01-14 | Latvias Organiskas Sintezes Instituts | Antidiabetes agent |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57175164A (en) * | 1981-04-18 | 1982-10-28 | Banyu Pharmaceut Co Ltd | 1,4-dihydropyridine derivative and its preparation |
DE3208628A1 (de) * | 1982-03-10 | 1983-09-22 | Bayer Ag, 5090 Leverkusen | Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
JPS58185821U (ja) * | 1982-06-02 | 1983-12-10 | 日産自動車株式会社 | ウインドシ−ルド |
DE3248548A1 (de) * | 1982-12-29 | 1984-07-05 | Heinrich Mack Nachf., 7918 Illertissen | Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE3316510A1 (de) * | 1983-05-06 | 1984-11-08 | Bayer Ag | Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen |
JPS60214778A (ja) * | 1984-03-08 | 1985-10-28 | Suntory Ltd | Ν置換3,4−ジヒドロピリミジン誘導体ならびにその製造法および用途 |
DE3544692A1 (de) * | 1985-12-18 | 1987-06-19 | Bayer Ag | Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670827C3 (de) * | 1967-03-20 | 1974-10-24 | Bayer Ag, 5090 Leverkusen | 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin |
DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
DE2117573C3 (de) * | 1971-04-10 | 1978-07-27 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von unsymmetrischen l,4-Dihydropyridin-3,5dicarbonsäureestern, sowie ihre Verwendung als Arzneimittel |
-
1976
- 1976-10-30 DE DE2650013A patent/DE2650013C3/de not_active Expired
-
1977
- 1977-10-06 US US05/840,065 patent/US4166855A/en not_active Expired - Lifetime
- 1977-10-25 GB GB44332/77A patent/GB1568740A/en not_active Expired
- 1977-10-25 CH CH1298277A patent/CH633265A5/de not_active IP Right Cessation
- 1977-10-27 NL NL7711827A patent/NL7711827A/xx not_active Application Discontinuation
- 1977-10-27 FI FI773208A patent/FI60705C/fi not_active IP Right Cessation
- 1977-10-27 SE SE7712108A patent/SE433211B/xx unknown
- 1977-10-28 ES ES463646A patent/ES463646A1/es not_active Expired
- 1977-10-28 AT AT773177A patent/AT357162B/de not_active IP Right Cessation
- 1977-10-28 FR FR7732558A patent/FR2369264A1/fr active Granted
- 1977-10-28 CA CA289,781A patent/CA1070314A/en not_active Expired
- 1977-10-28 BE BE182159A patent/BE860248A/xx not_active IP Right Cessation
- 1977-10-28 JP JP12881477A patent/JPS5356672A/ja active Granted
- 1977-10-28 AU AU30147/77A patent/AU507892B2/en not_active Expired
-
1981
- 1981-11-25 CH CH754481A patent/CH635078A5/de not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999001432A1 (ru) * | 1997-07-03 | 1999-01-14 | Latvias Organiskas Sintezes Instituts | Antidiabetes agent |
Also Published As
Publication number | Publication date |
---|---|
DE2650013B2 (de) | 1980-06-12 |
ES463646A1 (es) | 1978-07-16 |
FR2369264B1 (US07122547-20061017-C00273.png) | 1980-06-13 |
DE2650013C3 (de) | 1981-04-02 |
AT357162B (de) | 1980-06-25 |
ATA773177A (de) | 1979-11-15 |
US4166855A (en) | 1979-09-04 |
DE2650013A1 (de) | 1978-05-11 |
JPS577149B2 (US07122547-20061017-C00273.png) | 1982-02-09 |
JPS5356672A (en) | 1978-05-23 |
CH633265A5 (de) | 1982-11-30 |
CA1070314A (en) | 1980-01-22 |
BE860248A (fr) | 1978-04-28 |
AU3014777A (en) | 1979-05-03 |
FR2369264A1 (fr) | 1978-05-26 |
AU507892B2 (en) | 1980-02-28 |
FI60705B (fi) | 1981-11-30 |
NL7711827A (nl) | 1978-05-03 |
CH635078A5 (de) | 1983-03-15 |
SE7712108L (sv) | 1978-05-01 |
FI773208A (fi) | 1978-05-01 |
FI60705C (fi) | 1982-03-10 |
SE433211B (sv) | 1984-05-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |