GB1557757A - Process for preparing 16 methyl steroids - Google Patents
Process for preparing 16 methyl steroidsInfo
- Publication number
- GB1557757A GB1557757A GB1077878A GB1077878A GB1557757A GB 1557757 A GB1557757 A GB 1557757A GB 1077878 A GB1077878 A GB 1077878A GB 1077878 A GB1077878 A GB 1077878A GB 1557757 A GB1557757 A GB 1557757A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alpha
- acetoxypregna
- dioxo
- fluoro
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 methyl steroids Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000012043 crude product Substances 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- ALPZXIWEHIRQQD-JEIAQVDKSA-N 2-[(8S,9S,10R,13R,14S,17R)-10,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl]ethyl propanoate Chemical compound C1CC2=CCC=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](CCOC(=O)CC)[C@@]1(C)CC2 ALPZXIWEHIRQQD-JEIAQVDKSA-N 0.000 abstract 1
- AKUJBENLRBOFTD-HIBZCRSPSA-N [2-[(9r,10s,11s,13s,16r,17r)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)C1C1C[C@@H](C)[C@@](C(=O)COC(C)=O)(O)[C@@]1(C)C[C@@H]2O AKUJBENLRBOFTD-HIBZCRSPSA-N 0.000 abstract 1
- 239000012345 acetylating agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 150000002681 magnesium compounds Chemical class 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
- C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
- C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7708170A FR2383968A1 (fr) | 1977-03-18 | 1977-03-18 | Procede de preparation d'un steroide16a-methyle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1557757A true GB1557757A (en) | 1979-12-12 |
Family
ID=9188293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1077878A Expired GB1557757A (en) | 1977-03-18 | 1978-03-17 | Process for preparing 16 methyl steroids |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS53116362A (enExample) |
| BE (1) | BE865043A (enExample) |
| CA (1) | CA1117936A (enExample) |
| CH (1) | CH629223A5 (enExample) |
| DE (1) | DE2811540A1 (enExample) |
| FR (1) | FR2383968A1 (enExample) |
| GB (1) | GB1557757A (enExample) |
| HU (1) | HU174829B (enExample) |
| IE (1) | IE46586B1 (enExample) |
| NL (1) | NL7802927A (enExample) |
| PT (1) | PT67790A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2735501A1 (fr) * | 1995-06-15 | 1996-12-20 | Payen & Cie L | Procede pour la fabrication d'un fil guipe elastique et nouveau type de fil ainsi obtenu |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2244530B1 (enExample) * | 1973-07-27 | 1977-07-01 | Roussel Uclaf |
-
1977
- 1977-03-18 FR FR7708170A patent/FR2383968A1/fr active Granted
-
1978
- 1978-02-24 CA CA000297709A patent/CA1117936A/fr not_active Expired
- 1978-03-16 DE DE19782811540 patent/DE2811540A1/de active Granted
- 1978-03-17 CH CH294878A patent/CH629223A5/fr not_active IP Right Cessation
- 1978-03-17 PT PT6779078A patent/PT67790A/pt unknown
- 1978-03-17 JP JP3002378A patent/JPS53116362A/ja active Granted
- 1978-03-17 GB GB1077878A patent/GB1557757A/en not_active Expired
- 1978-03-17 BE BE186056A patent/BE865043A/xx not_active IP Right Cessation
- 1978-03-17 HU HU78RO971A patent/HU174829B/hu not_active IP Right Cessation
- 1978-03-17 NL NL7802927A patent/NL7802927A/xx not_active Application Discontinuation
- 1978-03-20 IE IE55378A patent/IE46586B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS53116362A (en) | 1978-10-11 |
| NL7802927A (nl) | 1978-09-20 |
| PT67790A (fr) | 1978-04-01 |
| IE46586B1 (en) | 1983-07-27 |
| FR2383968A1 (fr) | 1978-10-13 |
| DE2811540C2 (enExample) | 1987-09-10 |
| CH629223A5 (en) | 1982-04-15 |
| BE865043A (fr) | 1978-09-18 |
| HU174829B (hu) | 1980-03-28 |
| JPS6123799B2 (enExample) | 1986-06-07 |
| CA1117936A (fr) | 1982-02-09 |
| IE780553L (en) | 1978-09-18 |
| DE2811540A1 (de) | 1978-09-21 |
| FR2383968B1 (enExample) | 1980-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19940317 |