GB1541185A - 5-fluorouracil derivatives and their preparation - Google Patents
5-fluorouracil derivatives and their preparationInfo
- Publication number
- GB1541185A GB1541185A GB44960/77A GB4496077A GB1541185A GB 1541185 A GB1541185 A GB 1541185A GB 44960/77 A GB44960/77 A GB 44960/77A GB 4496077 A GB4496077 A GB 4496077A GB 1541185 A GB1541185 A GB 1541185A
- Authority
- GB
- United Kingdom
- Prior art keywords
- resulting
- preparation
- compounds
- reduction
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GHASVSINZRGABV-UHFFFAOYSA-N Fluorouracil Chemical class FC1=CNC(=O)NC1=O GHASVSINZRGABV-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229930182470 glycoside Natural products 0.000 abstract 1
- -1 glycoside halide Chemical class 0.000 abstract 1
- 150000002338 glycosides Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13020076A JPS5356677A (en) | 1976-10-28 | 1976-10-28 | 5-fluorouracil derivatives |
| JP4321477A JPS53135987A (en) | 1977-04-15 | 1977-04-15 | 5-fluorouracil derivative |
| JP5849277A JPS53144582A (en) | 1977-05-20 | 1977-05-20 | 5-fluorouracil derivatives |
| JP11037077A JPS5444681A (en) | 1977-09-13 | 1977-09-13 | 5-fluororacil derivative |
| JP11086777A JPS5444682A (en) | 1977-09-14 | 1977-09-14 | 5-fluorouracil derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1541185A true GB1541185A (en) | 1979-02-21 |
Family
ID=27522306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB44960/77A Expired GB1541185A (en) | 1976-10-28 | 1977-10-28 | 5-fluorouracil derivatives and their preparation |
Country Status (6)
| Country | Link |
|---|---|
| CH (3) | CH650006A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2748562A1 (enrdf_load_stackoverflow) |
| DK (1) | DK149818C (enrdf_load_stackoverflow) |
| FR (1) | FR2369296A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1541185A (enrdf_load_stackoverflow) |
| NL (1) | NL7711911A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5945406A (en) * | 1995-06-23 | 1999-08-31 | Oxford Glycosciences (Uk) Ltd. | Therapeutic compounds with pyrimidine base |
| US7271153B2 (en) | 2001-06-20 | 2007-09-18 | Kissei Pharmaceutical Co., Ltd. | Nitrogenous heterocyclic derivatives, medicinal compositions containing the same, medicinal uses thereof, and intermediates therefor |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9626450D0 (en) * | 1996-12-20 | 1997-02-05 | Oxford Glycosciences Uk Ltd | Therapeutic compounds |
-
1977
- 1977-10-27 DK DK478177A patent/DK149818C/da not_active IP Right Cessation
- 1977-10-28 GB GB44960/77A patent/GB1541185A/en not_active Expired
- 1977-10-28 CH CH2395/84A patent/CH650006A5/de not_active IP Right Cessation
- 1977-10-28 DE DE19772748562 patent/DE2748562A1/de not_active Ceased
- 1977-10-28 FR FR7732748A patent/FR2369296A1/fr active Granted
- 1977-10-28 CH CH1318477A patent/CH642974A5/de not_active IP Right Cessation
- 1977-10-28 NL NL7711911A patent/NL7711911A/xx not_active Application Discontinuation
-
1981
- 1981-12-15 CH CH800481A patent/CH643272A5/de not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5945406A (en) * | 1995-06-23 | 1999-08-31 | Oxford Glycosciences (Uk) Ltd. | Therapeutic compounds with pyrimidine base |
| US7271153B2 (en) | 2001-06-20 | 2007-09-18 | Kissei Pharmaceutical Co., Ltd. | Nitrogenous heterocyclic derivatives, medicinal compositions containing the same, medicinal uses thereof, and intermediates therefor |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7711911A (nl) | 1978-05-03 |
| DK149818C (da) | 1987-04-06 |
| FR2369296B1 (enrdf_load_stackoverflow) | 1982-06-11 |
| CH650006A5 (en) | 1985-06-28 |
| DK478177A (da) | 1978-04-29 |
| FR2369296A1 (fr) | 1978-05-26 |
| DK149818B (da) | 1986-10-06 |
| DE2748562A1 (de) | 1978-05-03 |
| CH643272A5 (en) | 1984-05-30 |
| CH642974A5 (en) | 1984-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19941028 |