GB1538822A - N-(benzthiazol-2-yl)-oxamic acid derivatives and the preparation thereof - Google Patents

N-(benzthiazol-2-yl)-oxamic acid derivatives and the preparation thereof

Info

Publication number
GB1538822A
GB1538822A GB50911/77A GB5091177A GB1538822A GB 1538822 A GB1538822 A GB 1538822A GB 50911/77 A GB50911/77 A GB 50911/77A GB 5091177 A GB5091177 A GB 5091177A GB 1538822 A GB1538822 A GB 1538822A
Authority
GB
United Kingdom
Prior art keywords
benzthiazol
preparation
acid derivatives
oxamic acid
oxamic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB50911/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1538822A publication Critical patent/GB1538822A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB50911/77A 1976-12-14 1977-12-07 N-(benzthiazol-2-yl)-oxamic acid derivatives and the preparation thereof Expired GB1538822A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762656468 DE2656468A1 (de) 1976-12-14 1976-12-14 N-(benzthiazol-2-yl)-oxamidsaeure- derivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
GB1538822A true GB1538822A (en) 1979-01-24

Family

ID=5995427

Family Applications (1)

Application Number Title Priority Date Filing Date
GB50911/77A Expired GB1538822A (en) 1976-12-14 1977-12-07 N-(benzthiazol-2-yl)-oxamic acid derivatives and the preparation thereof

Country Status (17)

Country Link
JP (1) JPS5377058A (enExample)
AR (1) AR216496A1 (enExample)
AT (1) AT360523B (enExample)
AU (1) AU510730B2 (enExample)
BE (1) BE861794A (enExample)
CS (1) CS203179B2 (enExample)
DD (1) DD133329A5 (enExample)
DE (1) DE2656468A1 (enExample)
ES (1) ES465034A1 (enExample)
FI (1) FI57594C (enExample)
FR (1) FR2374317A1 (enExample)
GB (1) GB1538822A (enExample)
HU (1) HU175340B (enExample)
NL (1) NL7713580A (enExample)
SE (1) SE7714074L (enExample)
SU (1) SU680647A3 (enExample)
ZA (1) ZA777236B (enExample)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321372A (en) 1980-06-16 1982-03-23 Pfizer Inc. Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides
FR2497805A1 (fr) * 1981-01-09 1982-07-16 Usv Pharma Corp Nouveaux composes heterocycliques, utiles comme agents antiallergiques
US4407810A (en) 1980-07-19 1983-10-04 Basf Aktiengesellschaft Thiazol-2-yl-oxamic acid derivatives, and therapeutic agents containing these compounds
EP0295656A1 (en) * 1987-06-17 1988-12-21 Eisai Co., Ltd. Benzothiazole derivative, its use, and pharmaceutical compositions comprising it
WO2001097786A3 (en) * 2000-06-21 2002-12-12 Hoffmann La Roche Benzothiazole derivatives
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
US7238808B2 (en) 2005-03-23 2007-07-03 Hoffmann-La Roche Inc. Acetylenyl-pyrazolo-pyrimidine derivatives
US7368446B2 (en) 2004-05-24 2008-05-06 Hoffmann-La Roche Inc. 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide
US7459563B2 (en) 2004-11-05 2008-12-02 Hoffmann-La Roche Inc. Process for the preparation of isonicotinic acid derivatives
US7504404B2 (en) 2005-09-27 2009-03-17 Hoffmann-La Roche Inc. Compounds as metabotropic glutamate receptor antagonists

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2676775A (en) * 1949-10-24 1954-04-27 Gustav O Schulz Electric flatiron cord holder
DE3017976A1 (de) * 1980-05-10 1981-11-19 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte 2-amino-5-halogen-benzothiazole, verfahen zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3135250A1 (de) * 1981-09-05 1983-03-17 Basf Ag, 6700 Ludwigshafen Tricyclische thiazolyloxamate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150140A (en) * 1976-12-23 1979-04-17 The Upjohn Company Benzothiazolyl oxanic acids, esters and salts

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321372A (en) 1980-06-16 1982-03-23 Pfizer Inc. Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides
US4407810A (en) 1980-07-19 1983-10-04 Basf Aktiengesellschaft Thiazol-2-yl-oxamic acid derivatives, and therapeutic agents containing these compounds
FR2497805A1 (fr) * 1981-01-09 1982-07-16 Usv Pharma Corp Nouveaux composes heterocycliques, utiles comme agents antiallergiques
EP0295656A1 (en) * 1987-06-17 1988-12-21 Eisai Co., Ltd. Benzothiazole derivative, its use, and pharmaceutical compositions comprising it
US7317007B2 (en) 2000-06-21 2008-01-08 Hoffmann-La Roche Inc. Benzothiazole derivatives with activity as adenosine receptor ligands
WO2001097786A3 (en) * 2000-06-21 2002-12-12 Hoffmann La Roche Benzothiazole derivatives
US6521754B2 (en) 2000-06-21 2003-02-18 Hoffman-La Roche Inc. Benzothiazole derivatives with activity as adenosine receptor ligands
US6835732B2 (en) 2000-06-21 2004-12-28 Hoffman-La Roche Inc. Benzothiazole derivatives with activity as adenosine receptor ligands
US6963000B2 (en) 2000-06-21 2005-11-08 Hoffman-La Roche Inc. Benzothiazole derivatives with activity as adenosine receptor ligands
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
US7368446B2 (en) 2004-05-24 2008-05-06 Hoffmann-La Roche Inc. 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide
US7459563B2 (en) 2004-11-05 2008-12-02 Hoffmann-La Roche Inc. Process for the preparation of isonicotinic acid derivatives
US7238808B2 (en) 2005-03-23 2007-07-03 Hoffmann-La Roche Inc. Acetylenyl-pyrazolo-pyrimidine derivatives
US7446113B2 (en) 2005-03-23 2008-11-04 Hoffman-La Roche Inc. Acetylenyl-pyrazolo-pyrimidine derivatives
US7718661B2 (en) 2005-03-23 2010-05-18 Hoffmann-La Roche Inc. Acetylenyl-pyrazolo-pyrimidine derivatives
US8063048B2 (en) 2005-03-23 2011-11-22 Hoffmann-La Roche Inc. Acetylenyl-pyrazolo-pyrimidine derivatives
US7504404B2 (en) 2005-09-27 2009-03-17 Hoffmann-La Roche Inc. Compounds as metabotropic glutamate receptor antagonists
US8093263B2 (en) 2005-09-27 2012-01-10 Hoffmann-La Roche Inc. Substituted pyrazolo [1,5-a] pyrimidines as metabotropic glutamate antagonists
US8349844B2 (en) 2005-09-27 2013-01-08 Hoffmann-La Roche Inc. Substituted pyrazolo [1,5-A] pyrimidines as metabotropic glutamate antagonists

Also Published As

Publication number Publication date
JPS5377058A (en) 1978-07-08
DE2656468A1 (de) 1978-06-15
NL7713580A (nl) 1978-06-16
SU680647A3 (ru) 1979-08-15
AU510730B2 (en) 1980-07-10
CS203179B2 (en) 1981-02-27
FI57594C (fi) 1980-09-10
FR2374317A1 (fr) 1978-07-13
ZA777236B (en) 1978-11-29
BE861794A (fr) 1978-06-13
AR216496A1 (es) 1979-12-28
AT360523B (de) 1981-01-12
SE7714074L (sv) 1978-06-15
DD133329A5 (de) 1978-12-27
FI773738A7 (fi) 1978-06-15
ES465034A1 (es) 1978-09-01
FI57594B (fi) 1980-05-30
AU3137777A (en) 1979-06-14
HU175340B (hu) 1980-07-28
FR2374317B1 (enExample) 1980-11-07
ATA890777A (de) 1980-06-15

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]