GB1537509A - Method of preparing a component consisting of sugar lipid and protein derived from pseudomonas aeruginosa which possesses anti-tumor and interferon-inducing properties - Google Patents
Method of preparing a component consisting of sugar lipid and protein derived from pseudomonas aeruginosa which possesses anti-tumor and interferon-inducing propertiesInfo
- Publication number
- GB1537509A GB1537509A GB5938/76A GB593876A GB1537509A GB 1537509 A GB1537509 A GB 1537509A GB 5938/76 A GB5938/76 A GB 5938/76A GB 593876 A GB593876 A GB 593876A GB 1537509 A GB1537509 A GB 1537509A
- Authority
- GB
- United Kingdom
- Prior art keywords
- weight
- pseudomonas aeruginosa
- protein
- sugar
- lipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 7
- 108090000623 proteins and genes Proteins 0.000 title abstract 7
- 241000589517 Pseudomonas aeruginosa Species 0.000 title abstract 5
- 150000002632 lipids Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 102000014150 Interferons Human genes 0.000 title abstract 2
- 108010050904 Interferons Proteins 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 230000001939 inductive effect Effects 0.000 title abstract 2
- 229940079322 interferon Drugs 0.000 title abstract 2
- 230000001064 anti-interferon Effects 0.000 title 1
- 235000018102 proteins Nutrition 0.000 abstract 6
- 108091005658 Basic proteases Proteins 0.000 abstract 4
- 230000001580 bacterial effect Effects 0.000 abstract 4
- 239000002158 endotoxin Substances 0.000 abstract 4
- 108091005804 Peptidases Proteins 0.000 abstract 3
- 102000035195 Peptidases Human genes 0.000 abstract 3
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 abstract 2
- 244000063299 Bacillus subtilis Species 0.000 abstract 1
- 235000014469 Bacillus subtilis Nutrition 0.000 abstract 1
- 108090000317 Chymotrypsin Proteins 0.000 abstract 1
- 108090000284 Pepsin A Proteins 0.000 abstract 1
- 102000057297 Pepsin A Human genes 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- 108090000631 Trypsin Proteins 0.000 abstract 1
- 102000004142 Trypsin Human genes 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229960002376 chymotrypsin Drugs 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000001962 electrophoresis Methods 0.000 abstract 1
- DNJIEGIFACGWOD-UHFFFAOYSA-N ethyl mercaptane Natural products CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 abstract 1
- 238000002523 gelfiltration Methods 0.000 abstract 1
- 150000002337 glycosamines Chemical class 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000005342 ion exchange Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 229940111202 pepsin Drugs 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 235000004252 protein component Nutrition 0.000 abstract 1
- 229960001322 trypsin Drugs 0.000 abstract 1
- 239000012588 trypsin Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/874—Pseudomonas
- Y10S435/875—Pseudomonas aeruginosa
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50055979A JPS51133489A (en) | 1975-05-14 | 1975-05-14 | Process for producing microbial components of pseudomonas aeruginosa h aving antimicrobial and antitumor activities |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1537509A true GB1537509A (en) | 1978-12-29 |
Family
ID=13014183
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5938/76A Expired GB1537509A (en) | 1975-05-14 | 1976-02-16 | Method of preparing a component consisting of sugar lipid and protein derived from pseudomonas aeruginosa which possesses anti-tumor and interferon-inducing properties |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4079126A (https=) |
| JP (1) | JPS51133489A (https=) |
| CA (1) | CA1060797A (https=) |
| DE (1) | DE2610504C2 (https=) |
| FR (1) | FR2311093A1 (https=) |
| GB (1) | GB1537509A (https=) |
| SE (1) | SE434701B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1085293A (en) * | 1976-02-05 | 1980-09-09 | Yuzuru Homma | Toxoids derived from protease and elastase of pseudomonas aeruginosa and production thereof |
| JPS5296729A (en) * | 1976-02-05 | 1977-08-13 | Shionogi & Co Ltd | Mixed vaccin for cyanomycosis |
| US4479935A (en) * | 1980-04-22 | 1984-10-30 | Institut Pasteur | Fractions extracted from aerobic bacteria, endowed with antitumoral, antibacterial and interferon inducing properties, and process for their preparation |
| CA1256370A (en) * | 1984-02-24 | 1989-06-27 | Yuzuru Homma | Toxoids of elastase of pseudomonas aeruginosa origin |
| AT384032B (de) * | 1985-01-14 | 1987-09-25 | Immuno Ag | Verfahren zur herstellung von polydispersen nativen pseudomonas-flagella(h)-antigenen (fag) |
| US5179001A (en) * | 1985-09-27 | 1993-01-12 | The Regents Of The University Of California | Detection and monitoring of chronic and gram-negative infection |
| AT391080B (de) * | 1986-06-24 | 1990-08-10 | Immuno Ag | Verfahren zur herstellung von gegen pseudomonas aeruginosa infektionen wirksamen praeparationen |
| US5237053A (en) * | 1986-06-24 | 1993-08-17 | Immuno Aktiengesellschaft | Preparation active against Pseudomonas aeruginosa infections and methods of producing them |
| FR2613380B1 (fr) * | 1987-04-06 | 1989-11-17 | Pasteur Institut | Nouvelle substance adjuvante de certains antimitotiques chimiques, procede d'obtention de cette substance a partir de cultures de vibrio cholerae, agents therapeutiques contenant ladite substance |
| AU6642390A (en) * | 1989-10-27 | 1991-05-31 | Arch Development Corporation | Methods and compositions for promoting immunopotentiation |
| US6406696B1 (en) | 1989-10-27 | 2002-06-18 | Tolerance Therapeutics, Inc. | Methods of stimulating the immune system with anti-CD3 antibodies |
| US20030108548A1 (en) * | 1993-06-01 | 2003-06-12 | Bluestone Jeffrey A. | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
| US6491916B1 (en) | 1994-06-01 | 2002-12-10 | Tolerance Therapeutics, Inc. | Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies |
| AU2006267090B2 (en) * | 2005-07-11 | 2013-03-07 | Provention Bio, Inc. | Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity |
| SG10201504662WA (en) * | 2006-06-14 | 2015-07-30 | Macrogenics Inc | Methods For The Treatment Of Autoimmune Disorders Using Immunosuppressive Monoclonal Antibodies With Reduced Toxicity |
| US20100015142A1 (en) * | 2006-12-21 | 2010-01-21 | Macrogenics Inc. | Methods for the treatment of lada and other adult- onset autoimmune using immunosuppressive monoclonal antibodies with reduced toxicity |
| KR20190060879A (ko) * | 2011-03-02 | 2019-06-03 | 제롬 쉔타그 | 단독으로 또는 c형 간염 바이러스 감염과 결합되는 간 지방증의 치료를 위한 조성물, 방법 및 진단 |
| CN109401992B (zh) * | 2017-08-18 | 2021-07-23 | 黑龙江省科学院微生物研究所 | 一株高产内毒素蛋白的铜绿假单胞菌及其应用 |
| US12565529B2 (en) | 2021-05-24 | 2026-03-03 | Provention Bio, Inc. | Methods for treating type 1 diabetes |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS496096B1 (https=) * | 1970-09-30 | 1974-02-12 | ||
| GB1365950A (en) * | 1970-10-20 | 1974-09-04 | Eisai Co Ltd | Pharmaceutical composition comprising a cell wall protein compo nent of pseudomonas aeruginosa |
| FR2184531B1 (https=) * | 1972-05-19 | 1975-10-17 | Anvar |
-
1975
- 1975-05-14 JP JP50055979A patent/JPS51133489A/ja active Granted
-
1976
- 1976-02-16 GB GB5938/76A patent/GB1537509A/en not_active Expired
- 1976-02-18 SE SE7601841A patent/SE434701B/xx unknown
- 1976-02-26 CA CA246,619A patent/CA1060797A/en not_active Expired
- 1976-03-01 FR FR7605759A patent/FR2311093A1/fr active Granted
- 1976-03-12 DE DE2610504A patent/DE2610504C2/de not_active Expired
- 1976-03-19 US US05/668,564 patent/US4079126A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6123167B2 (https=) | 1986-06-04 |
| FR2311093A1 (fr) | 1976-12-10 |
| FR2311093B1 (https=) | 1979-06-29 |
| SE434701B (sv) | 1984-08-13 |
| DE2610504C2 (de) | 1985-07-11 |
| US4079126A (en) | 1978-03-14 |
| DE2610504A1 (de) | 1976-11-25 |
| SE7601841L (sv) | 1976-11-15 |
| JPS51133489A (en) | 1976-11-19 |
| CA1060797A (en) | 1979-08-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |