GB1533297A - Prostaglandin analogues - Google Patents
Prostaglandin analoguesInfo
- Publication number
- GB1533297A GB1533297A GB4748276A GB4748276A GB1533297A GB 1533297 A GB1533297 A GB 1533297A GB 4748276 A GB4748276 A GB 4748276A GB 4748276 A GB4748276 A GB 4748276A GB 1533297 A GB1533297 A GB 1533297A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- formula
- alkyl
- cyclodextrin clathrates
- those compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940006138 antiglaucoma drug and miotics prostaglandin analogues Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 11
- 229920000858 Cyclodextrin Polymers 0.000 abstract 4
- 125000001589 carboacyl group Chemical group 0.000 abstract 4
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 3
- 230000010933 acylation Effects 0.000 abstract 2
- 238000005917 acylation reaction Methods 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4748276A GB1533297A (en) | 1976-11-15 | 1976-11-15 | Prostaglandin analogues |
| JP13719377A JPS5382758A (en) | 1976-11-15 | 1977-11-14 | Preparation of analogue of prostaglandin |
| FR7734121A FR2370728A1 (fr) | 1976-11-15 | 1977-11-14 | Nouveaux derives de phenyl-15 pentanor-prostaglandines, leur preparation et les compositions pharmaceutiques qui les contiennent |
| DE19772751062 DE2751062A1 (de) | 1976-11-15 | 1977-11-15 | Prostaglandinanaloge, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4748276A GB1533297A (en) | 1976-11-15 | 1976-11-15 | Prostaglandin analogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1533297A true GB1533297A (en) | 1978-11-22 |
Family
ID=10445145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4748276A Expired GB1533297A (en) | 1976-11-15 | 1976-11-15 | Prostaglandin analogues |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS5382758A (enrdf_load_stackoverflow) |
| DE (1) | DE2751062A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2370728A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1533297A (enrdf_load_stackoverflow) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL45173A0 (en) * | 1973-07-30 | 1974-10-22 | Miles Lab | Cyclopentylheptanoic and-cis-5-heptanoic acid derivatives |
-
1976
- 1976-11-15 GB GB4748276A patent/GB1533297A/en not_active Expired
-
1977
- 1977-11-14 FR FR7734121A patent/FR2370728A1/fr active Granted
- 1977-11-14 JP JP13719377A patent/JPS5382758A/ja active Pending
- 1977-11-15 DE DE19772751062 patent/DE2751062A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| FR2370728B1 (enrdf_load_stackoverflow) | 1980-04-25 |
| FR2370728A1 (fr) | 1978-06-09 |
| JPS5382758A (en) | 1978-07-21 |
| DE2751062A1 (de) | 1978-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |