GB1532672A - Process for the preparation of amoxicillin trihydrate - Google Patents

Process for the preparation of amoxicillin trihydrate

Info

Publication number
GB1532672A
GB1532672A GB3023976A GB3023976A GB1532672A GB 1532672 A GB1532672 A GB 1532672A GB 3023976 A GB3023976 A GB 3023976A GB 3023976 A GB3023976 A GB 3023976A GB 1532672 A GB1532672 A GB 1532672A
Authority
GB
United Kingdom
Prior art keywords
preparation
amoxicillin trihydrate
amoxicillin
trihydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3023976A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Priority to GB3023976A priority Critical patent/GB1532672A/en
Priority to GR53736A priority patent/GR69921B/el
Priority to ES460026A priority patent/ES460026A1/es
Priority to JP8517077A priority patent/JPS5315397A/ja
Priority to DE19772732528 priority patent/DE2732528A1/de
Publication of GB1532672A publication Critical patent/GB1532672A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • C07D499/68—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB3023976A 1976-07-20 1976-07-20 Process for the preparation of amoxicillin trihydrate Expired GB1532672A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB3023976A GB1532672A (en) 1976-07-20 1976-07-20 Process for the preparation of amoxicillin trihydrate
GR53736A GR69921B (es) 1976-07-20 1977-06-18
ES460026A ES460026A1 (es) 1976-07-20 1977-06-22 Un procedimiento mejorado para la preparacion de trihidrato de amoxicilina cristalino.
JP8517077A JPS5315397A (en) 1976-07-20 1977-07-18 Chemical method
DE19772732528 DE2732528A1 (de) 1976-07-20 1977-07-19 Verfahren zur herstellung von amoxicillintrihydrat

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3023976A GB1532672A (en) 1976-07-20 1976-07-20 Process for the preparation of amoxicillin trihydrate

Publications (1)

Publication Number Publication Date
GB1532672A true GB1532672A (en) 1978-11-15

Family

ID=10304500

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3023976A Expired GB1532672A (en) 1976-07-20 1976-07-20 Process for the preparation of amoxicillin trihydrate

Country Status (5)

Country Link
JP (1) JPS5315397A (es)
DE (1) DE2732528A1 (es)
ES (1) ES460026A1 (es)
GB (1) GB1532672A (es)
GR (1) GR69921B (es)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2240102A (en) * 1990-01-22 1991-07-24 Biochemie Gmbh Beta-lactam production
CN101845053A (zh) * 2010-03-09 2010-09-29 河北科技大学 一种分离提纯阿莫西林三水化合物的方法
CN103145733A (zh) * 2013-03-20 2013-06-12 四川省惠达药业有限公司 一种阿莫西林化合物及该化合物和克拉维酸钾的药物组合物
CN104059086A (zh) * 2014-06-19 2014-09-24 河南牧翔动物药业有限公司 一种阿莫西林晶体及其制备方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0408403A (pt) * 2003-03-21 2006-03-21 Dsm Ip Assets Bv pó cristalino de triidrato de amoxicilina
CN105061468B (zh) * 2015-09-23 2018-07-06 河北远征药业有限公司 一种阿莫西林缓释晶体的制备方法
CN106399446B (zh) * 2016-11-04 2021-05-04 内蒙古常盛制药有限公司 一种由脱酯液制备阿莫西林的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1347979A (en) * 1970-11-12 1974-02-27 Beecham Group Ltd Penicillins
JPS5318515B2 (es) * 1971-12-17 1978-06-15
ES401263A1 (es) * 1972-03-28 1975-02-16 Beecham Group Ltd Un procedimiento para la produccion de alfa - amino-(p-hi- droxibencil) penicilina.

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2240102A (en) * 1990-01-22 1991-07-24 Biochemie Gmbh Beta-lactam production
GB2240102B (en) * 1990-01-22 1993-10-20 Biochemie Gmbh Improvements in or relating to beta lactam production
CN101845053A (zh) * 2010-03-09 2010-09-29 河北科技大学 一种分离提纯阿莫西林三水化合物的方法
CN101845053B (zh) * 2010-03-09 2012-07-25 河北科技大学 一种分离提纯阿莫西林三水化合物的方法
CN103145733A (zh) * 2013-03-20 2013-06-12 四川省惠达药业有限公司 一种阿莫西林化合物及该化合物和克拉维酸钾的药物组合物
CN103145733B (zh) * 2013-03-20 2014-02-26 四川省惠达药业有限公司 一种阿莫西林化合物及该化合物和克拉维酸钾的药物组合物
CN104059086A (zh) * 2014-06-19 2014-09-24 河南牧翔动物药业有限公司 一种阿莫西林晶体及其制备方法

Also Published As

Publication number Publication date
JPS5315397A (en) 1978-02-13
DE2732528A1 (de) 1978-01-26
ES460026A1 (es) 1978-11-16
GR69921B (es) 1982-07-21

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee