GB1521712A - 5-acetyl-4-hydroxy-2h-pyran-2,6(3h)dione derivatives and pharmaceutical compositions comprising such compounds - Google Patents

5-acetyl-4-hydroxy-2h-pyran-2,6(3h)dione derivatives and pharmaceutical compositions comprising such compounds

Info

Publication number
GB1521712A
GB1521712A GB30936/75A GB3093675A GB1521712A GB 1521712 A GB1521712 A GB 1521712A GB 30936/75 A GB30936/75 A GB 30936/75A GB 3093675 A GB3093675 A GB 3093675A GB 1521712 A GB1521712 A GB 1521712A
Authority
GB
United Kingdom
Prior art keywords
pyran
compounds
acetyl
hydroxy
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB30936/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of GB1521712A publication Critical patent/GB1521712A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Compounds of the formula <IMAGE> and their tautomers suppress the antigen-antibody response. They are prepared by reacting 3,5-diacetyl-4,6-dihydroxy-2H-pyran-2-one with an amine of the general formula II R-NH2 (II> in which R has the meaning given in Patent Claim 1, and, if appropriate, converting the product with an alkali metal alcoholate into its mono- or dialkali metal salts.
GB30936/75A 1974-07-29 1975-07-24 5-acetyl-4-hydroxy-2h-pyran-2,6(3h)dione derivatives and pharmaceutical compositions comprising such compounds Expired GB1521712A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49264074A 1974-07-29 1974-07-29
US57089675A 1975-04-23 1975-04-23

Publications (1)

Publication Number Publication Date
GB1521712A true GB1521712A (en) 1978-08-16

Family

ID=27050812

Family Applications (1)

Application Number Title Priority Date Filing Date
GB30936/75A Expired GB1521712A (en) 1974-07-29 1975-07-24 5-acetyl-4-hydroxy-2h-pyran-2,6(3h)dione derivatives and pharmaceutical compositions comprising such compounds

Country Status (17)

Country Link
JP (1) JPS5136458A (en)
AT (1) AT343657B (en)
CA (1) CA1064509A (en)
CH (1) CH615433A5 (en)
DD (1) DD118626A5 (en)
DE (1) DE2533843C2 (en)
DK (1) DK134552B (en)
ES (1) ES439664A1 (en)
FI (1) FI59406C (en)
FR (1) FR2280367A1 (en)
GB (1) GB1521712A (en)
HU (1) HU174067B (en)
IE (1) IE41709B1 (en)
IL (1) IL47792A (en)
LU (1) LU73066A1 (en)
NL (1) NL7509032A (en)
NO (1) NO142668C (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1572271A (en) * 1976-06-16 1980-07-30 Smithkline Corp 5-acetyl-4-hydroxy-(3(1-phenylaminoethylidene)-2h-pyran-2,6(3h)-dione derivatives
FR2388808A1 (en) * 1977-04-29 1978-11-24 Smithkline Corp SUBSTITUTE DERIVATIVES OF 2H-PYRANNE-2,6 (3H) -DIONES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
US4160021A (en) * 1977-05-23 1979-07-03 Smithkline Corporation Substituted 2H-pyran-2,6(3H)-dione derivatives
US5263435A (en) * 1992-08-12 1993-11-23 Mitsuba Electric Manufacturing Co., Ltd. Volute horn and method of manufacturing

Also Published As

Publication number Publication date
ATA584475A (en) 1977-10-15
NO752638L (en) 1976-01-30
DE2533843A1 (en) 1976-02-19
FI59406B (en) 1981-04-30
NL7509032A (en) 1976-02-02
DE2533843C2 (en) 1984-06-14
JPS5136458A (en) 1976-03-27
FI752139A (en) 1976-01-30
DK134552B (en) 1976-11-29
CH615433A5 (en) 1980-01-31
ES439664A1 (en) 1977-03-01
FR2280367B1 (en) 1979-08-10
IE41709L (en) 1976-01-29
IE41709B1 (en) 1980-03-12
HU174067B (en) 1979-10-28
FR2280367A1 (en) 1976-02-27
DK134552C (en) 1977-05-09
NO142668C (en) 1980-09-24
DD118626A5 (en) 1976-03-12
LU73066A1 (en) 1976-03-02
IL47792A (en) 1978-06-15
CA1064509A (en) 1979-10-16
NO142668B (en) 1980-06-16
DK332675A (en) 1976-01-30
AU8345075A (en) 1977-02-03
AT343657B (en) 1978-06-12
FI59406C (en) 1981-08-10
IL47792A0 (en) 1975-10-15

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee