GB1511517A - Alpha-(diethylamino)-propiophenone orotate a process for its preparation and its use in pharmaceutical compositions - Google Patents
Alpha-(diethylamino)-propiophenone orotate a process for its preparation and its use in pharmaceutical compositionsInfo
- Publication number
- GB1511517A GB1511517A GB3774275A GB3774275A GB1511517A GB 1511517 A GB1511517 A GB 1511517A GB 3774275 A GB3774275 A GB 3774275A GB 3774275 A GB3774275 A GB 3774275A GB 1511517 A GB1511517 A GB 1511517A
- Authority
- GB
- United Kingdom
- Prior art keywords
- propiophenone
- diethylamino
- orotate
- pharmaceutical compositions
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- QUUZZUYLUSVICE-UHFFFAOYSA-N 2-(diethylamino)-1-phenylpropan-1-one 2,4-dioxo-1H-pyrimidine-6-carboxylic acid Chemical compound C(C1=CC(=O)NC(=O)N1)(=O)O.C(C)N(C(C(=O)C1=CC=CC=C1)C)CC QUUZZUYLUSVICE-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- XXEPPPIWZFICOJ-UHFFFAOYSA-N diethylpropion Chemical compound CCN(CC)C(C)C(=O)C1=CC=CC=C1 XXEPPPIWZFICOJ-UHFFFAOYSA-N 0.000 abstract 2
- PXQPEWDEAKTCGB-UHFFFAOYSA-N orotic acid Chemical compound OC(=O)C1=CC(=O)NC(=O)N1 PXQPEWDEAKTCGB-UHFFFAOYSA-N 0.000 abstract 2
- 239000002830 appetite depressant Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229960005010 orotic acid Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/557—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. orotic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7431553A FR2285120A1 (fr) | 1974-09-18 | 1974-09-18 | Orotate de 2-(diethylamino)-1-phenyl-propanone et son procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1511517A true GB1511517A (en) | 1978-05-17 |
Family
ID=9143207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3774275A Expired GB1511517A (en) | 1974-09-18 | 1975-09-15 | Alpha-(diethylamino)-propiophenone orotate a process for its preparation and its use in pharmaceutical compositions |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS5161616A (enrdf_load_stackoverflow) |
| BE (1) | BE833524A (enrdf_load_stackoverflow) |
| CH (1) | CH572912A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2541429A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2285120A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1511517A (enrdf_load_stackoverflow) |
| LU (1) | LU73413A1 (enrdf_load_stackoverflow) |
| NL (1) | NL7510895A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999018083A1 (en) * | 1997-10-07 | 1999-04-15 | Alexandr Leonidovich Reshetov | N,n'-(sulphonyldi-1, 4-phenylen) bis (n'',n''- dimethylformamidin)-1, 2,3,4-tetrahydro- 6-methyl-2, 4-dioxo-5-pyrimidinsulphonate for stimulating cellular metabolism and having an immunotropic and anti-bacterial activity and method for producing the same |
| EP1031570A4 (en) * | 1997-08-12 | 2001-09-26 | Reshetov Alexandr Leonidovich | IMMUNOLOGICAL MODULATOR HAVING ANTIMICROBIAL AND ANTI-MYCOBACTERIAL ACTIVITY, PROCESS FOR PRODUCING THE MODULATOR AND PHARMACEUTICAL PREPARATION FOR TREATING MYCOBACTERIOSIS AS WELL AS CHRONIC AND NON-SPECIFIC DISEASES OF DISEASE, LUNG |
-
1974
- 1974-09-18 FR FR7431553A patent/FR2285120A1/fr active Granted
-
1975
- 1975-09-02 CH CH1135475A patent/CH572912A5/xx not_active IP Right Cessation
- 1975-09-15 GB GB3774275A patent/GB1511517A/en not_active Expired
- 1975-09-16 JP JP11202575A patent/JPS5161616A/ja active Pending
- 1975-09-16 NL NL7510895A patent/NL7510895A/xx not_active Application Discontinuation
- 1975-09-16 LU LU73413A patent/LU73413A1/xx unknown
- 1975-09-17 DE DE19752541429 patent/DE2541429A1/de not_active Withdrawn
- 1975-09-17 BE BE160133A patent/BE833524A/xx not_active IP Right Cessation
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1031570A4 (en) * | 1997-08-12 | 2001-09-26 | Reshetov Alexandr Leonidovich | IMMUNOLOGICAL MODULATOR HAVING ANTIMICROBIAL AND ANTI-MYCOBACTERIAL ACTIVITY, PROCESS FOR PRODUCING THE MODULATOR AND PHARMACEUTICAL PREPARATION FOR TREATING MYCOBACTERIOSIS AS WELL AS CHRONIC AND NON-SPECIFIC DISEASES OF DISEASE, LUNG |
| WO1999018083A1 (en) * | 1997-10-07 | 1999-04-15 | Alexandr Leonidovich Reshetov | N,n'-(sulphonyldi-1, 4-phenylen) bis (n'',n''- dimethylformamidin)-1, 2,3,4-tetrahydro- 6-methyl-2, 4-dioxo-5-pyrimidinsulphonate for stimulating cellular metabolism and having an immunotropic and anti-bacterial activity and method for producing the same |
| RU2136668C1 (ru) * | 1997-10-07 | 1999-09-10 | Голощапов Николай Михайлович | N,n'-(сульфонилди-1,4-фенилен)бис(n'',n''- диметилформамидин)1,2,3,4-тетрагидро-6-метил-2,4- диоксо-5-пиримидинсульфонат, стимулирующий клеточный метаболизм и обладающий иммунотропной и антимикобактериальной активностью |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7510895A (nl) | 1976-03-22 |
| FR2285120B1 (enrdf_load_stackoverflow) | 1978-07-21 |
| BE833524A (fr) | 1976-01-16 |
| CH572912A5 (enrdf_load_stackoverflow) | 1976-02-27 |
| LU73413A1 (enrdf_load_stackoverflow) | 1976-04-13 |
| JPS5161616A (en) | 1976-05-28 |
| DE2541429A1 (de) | 1976-04-01 |
| FR2285120A1 (fr) | 1976-04-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1445967A (en) | Bispidine and bispidone derivatives | |
| ES8800272A1 (es) | Un procedimiento para la preparacion de polipeptidos. | |
| ES447010A1 (es) | Procedimiento para preparar 1-(3, 3, 3-triarifpropil-4-fe- nil)-4-piperidinamotanoles. | |
| IE38979B1 (en) | Amides derived from quinoxaline | |
| GB1511517A (en) | Alpha-(diethylamino)-propiophenone orotate a process for its preparation and its use in pharmaceutical compositions | |
| NL179059C (nl) | Werkwijze ter bereiding van een geneesmiddel met ontstekingsremmende werking, gevormd geneesmiddel en werkwijze ter bereiding van geneeskrachtige verbindingen, geschikt voor gebruik bij deze werkwijze. | |
| IE33371L (en) | Protozoacids; aminoguanidine derivatives | |
| GB1465783A (en) | Pyrrolyl compounds and processes for their manufacture | |
| EP0189916A3 (en) | 3-(pyrrolidinio)methyl-3-cephem derivatives, pharmaceutical composition and process for the production thereof | |
| IE39800B1 (en) | 4-amino-3-hydrazino-1 2 4-triazole derivatives methods fortheir preparation and compositions containing them | |
| GB2118546B (en) | 7-oxo-4-thia-1-azabicyclo(3,2,0)heptane derivatives | |
| IE44230L (en) | 1, 3-diaza-bicyclo [3,2, 0] heptane derivatives | |
| GB1313443A (en) | Triiodo-phenylalkyl ethers their application in x-ray contrast agents and process for their production | |
| ES8304923A1 (es) | Un procedimiento para la preparacion de un peptido. | |
| IE33837B1 (en) | Pharmaceutical compositions | |
| GB1421685A (en) | Phenoxyalkanecarboxylic acid derivative the preparation thereof and pharmaceutical compositions containing it | |
| ES449917A1 (es) | Un procedimiento para la preparacion de acidos (1-oxo-2-arilo tienil-2-sustituido-5-indaniloxi (o tio)) alcanoicos. | |
| GB1507463A (en) | N-(1-benzylpiperid-4-yl)-benzamides methods for their preparation and pharmaceutical compositions containing them | |
| GB1527941A (en) | 1-(3-phenylpropyl)-4-(beta-alkoxyacryloyl)piperazine derivatives | |
| GB1477263A (en) | Thiamindisulphidemono-orotate and process for its preparation | |
| GB1289039A (enrdf_load_stackoverflow) | ||
| GB1472937A (en) | Benzyl alcohol derivatives | |
| GB1249643A (en) | New proline derivatives and process for the preparation thereof | |
| GB1237158A (en) | Pharmaceutical compositions containing and process for preparing a benzodiopane derivative | |
| GB1434645A (en) | Tetrazole coumarin derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |