GB1507258A - 1-hydroxy-1-methyl-1,3-dihydrofuro(3,4-b)quinoxaline 4,9-dioxide and derivatives thereof - Google Patents
1-hydroxy-1-methyl-1,3-dihydrofuro(3,4-b)quinoxaline 4,9-dioxide and derivatives thereofInfo
- Publication number
- GB1507258A GB1507258A GB31133/76A GB3113376A GB1507258A GB 1507258 A GB1507258 A GB 1507258A GB 31133/76 A GB31133/76 A GB 31133/76A GB 3113376 A GB3113376 A GB 3113376A GB 1507258 A GB1507258 A GB 1507258A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dioxide
- compounds
- quinoxaline
- prepared
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- IRRITUGKFJKONO-UHFFFAOYSA-N 3-methyl-9-oxido-4-oxo-1h-furo[3,4-b]quinoxalin-4-ium-3-ol Chemical compound [O-][N+]1=C2C=CC=CC2=[N+]([O-])C2=C1C(C)(O)OC2 IRRITUGKFJKONO-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000000845 anti-microbial effect Effects 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- CUJMCPPBTUATEJ-UHFFFAOYSA-N 1-(3-methyl-4-oxido-1-oxoquinoxalin-1-ium-2-yl)ethanone Chemical compound C1=CC=C2[N+](=O)C(C(=O)C)=C(C)N([O-])C2=C1 CUJMCPPBTUATEJ-UHFFFAOYSA-N 0.000 abstract 1
- XCWKWJNAWMIHBG-UHFFFAOYSA-N 1-(oxan-2-yloxy)pentane-2,4-dione Chemical compound CC(=O)CC(=O)COC1CCCCO1 XCWKWJNAWMIHBG-UHFFFAOYSA-N 0.000 abstract 1
- PXYRHMIAMMKSOB-UHFFFAOYSA-N 1-[3-(oxan-2-yloxymethyl)-4-oxido-1-oxoquinoxalin-1-ium-2-yl]ethanone Chemical compound [O-][N+]1=C2C=CC=CC2=[N+]([O-])C(C(=O)C)=C1COC1CCCCO1 PXYRHMIAMMKSOB-UHFFFAOYSA-N 0.000 abstract 1
- -1 2-tetrahydropyranyl Chemical group 0.000 abstract 1
- USINKCFNVJGNEW-UHFFFAOYSA-N 3-methyl-4,9-dioxido-1,3-dihydrofuro[3,4-b]quinoxaline-4,9-diium Chemical class CC1OCC=2C1=[N+](C1=CC=CC=C1[N+]=2[O-])[O-] USINKCFNVJGNEW-UHFFFAOYSA-N 0.000 abstract 1
- OKEAMBAZBICIFP-UHFFFAOYSA-N 3-oxido-2,1,3-benzoxadiazol-3-ium Chemical compound C1=CC=CC2=[N+]([O-])ON=C21 OKEAMBAZBICIFP-UHFFFAOYSA-N 0.000 abstract 1
- BUDQDWGNQVEFAC-UHFFFAOYSA-N Dihydropyran Chemical compound C1COC=CC1 BUDQDWGNQVEFAC-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- GZVWKAGBBACFPD-UHFFFAOYSA-N ethyl 2-(oxan-2-yloxy)acetate Chemical compound CCOC(=O)COC1CCCCO1 GZVWKAGBBACFPD-UHFFFAOYSA-N 0.000 abstract 1
- ZANNOFHADGWOLI-UHFFFAOYSA-N ethyl 2-hydroxyacetate Chemical compound CCOC(=O)CO ZANNOFHADGWOLI-UHFFFAOYSA-N 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000003973 paint Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 abstract 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 1
- 238000004321 preservation Methods 0.000 abstract 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 1
- 239000002023 wood Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/602,514 US3991053A (en) | 1975-08-06 | 1975-08-06 | Antibacterial 1,3-dihydrofuro[3,4-b]quinoxaline 4,9-dioxides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1507258A true GB1507258A (en) | 1978-04-12 |
Family
ID=24411661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB31133/76A Expired GB1507258A (en) | 1975-08-06 | 1976-07-26 | 1-hydroxy-1-methyl-1,3-dihydrofuro(3,4-b)quinoxaline 4,9-dioxide and derivatives thereof |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3991053A (enExample) |
| JP (1) | JPS5219698A (enExample) |
| BE (1) | BE842300A (enExample) |
| DE (1) | DE2632924C2 (enExample) |
| FR (1) | FR2320100A1 (enExample) |
| GB (1) | GB1507258A (enExample) |
| IT (1) | IT1066083B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4060523A (en) * | 1975-08-06 | 1977-11-29 | Pfizer Inc. | 1-Alkoxy-1-substituted phenyl-1,3-dehydrofuro[3,4-b]quinoxaline-4,9-dioxides |
| FR2350096A1 (fr) * | 1976-05-03 | 1977-12-02 | Oreal | Compositions destinees a la coloration de la peau a base de derives de la quinoxaline |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3344022A (en) * | 1964-08-31 | 1967-09-26 | Pfizer & Co C | Method of treating chronic respiratory disease in poultry |
-
1975
- 1975-08-06 US US05/602,514 patent/US3991053A/en not_active Expired - Lifetime
-
1976
- 1976-05-28 BE BE1007419A patent/BE842300A/xx not_active IP Right Cessation
- 1976-05-28 IT IT49703/76A patent/IT1066083B/it active
- 1976-05-28 JP JP51062202A patent/JPS5219698A/ja active Granted
- 1976-05-31 FR FR7616360A patent/FR2320100A1/fr active Granted
- 1976-07-22 DE DE2632924A patent/DE2632924C2/de not_active Expired
- 1976-07-26 GB GB31133/76A patent/GB1507258A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2632924C2 (de) | 1983-05-26 |
| IT1066083B (it) | 1985-03-04 |
| FR2320100A1 (fr) | 1977-03-04 |
| BE842300A (fr) | 1976-11-29 |
| DE2632924A1 (de) | 1977-02-10 |
| FR2320100B1 (enExample) | 1980-04-11 |
| JPS5219698A (en) | 1977-02-15 |
| JPS548679B2 (enExample) | 1979-04-17 |
| US3991053A (en) | 1976-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |