GB1507199A - 11beta-alkyl-2-azaestratrienes - Google Patents
11beta-alkyl-2-azaestratrienesInfo
- Publication number
- GB1507199A GB1507199A GB18665/75A GB1866575A GB1507199A GB 1507199 A GB1507199 A GB 1507199A GB 18665/75 A GB18665/75 A GB 18665/75A GB 1866575 A GB1866575 A GB 1866575A GB 1507199 A GB1507199 A GB 1507199A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- heterosteroids
- formula
- ols
- alk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- -1 5,6 - dihydro - 3- substitutedisoquinol - 8 - yl Chemical group 0.000 abstract 2
- MZRVEZGGRBJDDB-UHFFFAOYSA-N N-Butyllithium Chemical compound [Li]CCCC MZRVEZGGRBJDDB-UHFFFAOYSA-N 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 125000006564 (C4-C8) cycloalkyl group Chemical group 0.000 abstract 1
- HXZILEQYFQYQCE-UHFFFAOYSA-N 2-methylcyclopentane-1,3-dione Chemical compound CC1C(=O)CCC1=O HXZILEQYFQYQCE-UHFFFAOYSA-N 0.000 abstract 1
- WFZAOWUFFCIBNP-UHFFFAOYSA-N 6,7-dihydro-5h-isoquinolin-8-one Chemical class C1=NC=C2C(=O)CCCC2=C1 WFZAOWUFFCIBNP-UHFFFAOYSA-N 0.000 abstract 1
- FJNCXZZQNBKEJT-UHFFFAOYSA-N 8beta-hydroxymarrubiin Natural products O1C(=O)C2(C)CCCC3(C)C2C1CC(C)(O)C3(O)CCC=1C=COC=1 FJNCXZZQNBKEJT-UHFFFAOYSA-N 0.000 abstract 1
- 101100490437 Mus musculus Acvrl1 gene Proteins 0.000 abstract 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000000055 hyoplipidemic effect Effects 0.000 abstract 1
- 150000002537 isoquinolines Chemical class 0.000 abstract 1
- 150000002642 lithium compounds Chemical class 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/467,217 US4007194A (en) | 1974-05-06 | 1974-05-06 | Process and intermediates for manufacture of 2-azasterioids |
| US05/543,027 US4012391A (en) | 1974-05-06 | 1975-01-22 | 11β-Alkyl-2-azaestratrienes and intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1507199A true GB1507199A (en) | 1978-04-12 |
Family
ID=27041961
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB18665/75A Expired GB1507199A (en) | 1974-05-06 | 1975-05-05 | 11beta-alkyl-2-azaestratrienes |
| GB33589/76A Expired GB1507200A (en) | 1974-05-06 | 1975-05-05 | 7-aza-1-tetralones |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB33589/76A Expired GB1507200A (en) | 1974-05-06 | 1975-05-05 | 7-aza-1-tetralones |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4012391A (enExample) |
| JP (1) | JPS50151876A (enExample) |
| CA (1) | CA1050965A (enExample) |
| DE (1) | DE2520013A1 (enExample) |
| FR (1) | FR2269945B1 (enExample) |
| GB (2) | GB1507199A (enExample) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3887567A (en) * | 1970-12-21 | 1975-06-03 | Searle & Co | 3-Alkoxy-2-azaestratrienes |
-
1975
- 1975-01-22 US US05/543,027 patent/US4012391A/en not_active Expired - Lifetime
- 1975-05-05 CA CA226,252A patent/CA1050965A/en not_active Expired
- 1975-05-05 GB GB18665/75A patent/GB1507199A/en not_active Expired
- 1975-05-05 FR FR7513981A patent/FR2269945B1/fr not_active Expired
- 1975-05-05 DE DE19752520013 patent/DE2520013A1/de not_active Withdrawn
- 1975-05-05 GB GB33589/76A patent/GB1507200A/en not_active Expired
- 1975-05-06 JP JP50054178A patent/JPS50151876A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE2520013A1 (de) | 1975-11-20 |
| JPS50151876A (enExample) | 1975-12-06 |
| US4012391A (en) | 1977-03-15 |
| CA1050965A (en) | 1979-03-20 |
| GB1507200A (en) | 1978-04-12 |
| FR2269945B1 (enExample) | 1978-07-28 |
| FR2269945A1 (enExample) | 1975-12-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |