GB1498495A - 2-amino-6-tertiary aminodihydropyridines their production and their medicinal use - Google Patents
2-amino-6-tertiary aminodihydropyridines their production and their medicinal useInfo
- Publication number
- GB1498495A GB1498495A GB5312/75A GB531275A GB1498495A GB 1498495 A GB1498495 A GB 1498495A GB 5312/75 A GB5312/75 A GB 5312/75A GB 531275 A GB531275 A GB 531275A GB 1498495 A GB1498495 A GB 1498495A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- compounds
- amino
- pyridyl
- feb
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FDHRGQIRBRQMPF-UHFFFAOYSA-N 2h-pyridin-1-amine Chemical group NN1CC=CC=C1 FDHRGQIRBRQMPF-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004076 pyridyl group Chemical group 0.000 abstract 2
- MLIREBYILWEBDM-UHFFFAOYSA-M 2-cyanoacetate Chemical compound [O-]C(=O)CC#N MLIREBYILWEBDM-UHFFFAOYSA-M 0.000 abstract 1
- 125000002015 acyclic group Chemical group 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003440 anti-fibrillation Effects 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 230000000916 dilatatory effect Effects 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002183 isoquinolinyl group Chemical group C1(=NC=CC2=CC=CC=C12)* 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000006501 nitrophenyl group Chemical group 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 125000002112 pyrrolidino group Chemical group [*]N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2406198A DE2406198C2 (de) | 1974-02-09 | 1974-02-09 | Verfahren zur Herstellung von neuen 2-Amino-6-dialkylamino-dihydropyridinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1498495A true GB1498495A (en) | 1978-01-18 |
Family
ID=5906982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5312/75A Expired GB1498495A (en) | 1974-02-09 | 1975-02-07 | 2-amino-6-tertiary aminodihydropyridines their production and their medicinal use |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4004014A (en, 2012) |
| JP (1) | JPS5943460B2 (en, 2012) |
| AT (1) | AT342590B (en, 2012) |
| BE (1) | BE825245A (en, 2012) |
| CA (1) | CA1032539A (en, 2012) |
| CH (2) | CH605754A5 (en, 2012) |
| DD (1) | DD117452A5 (en, 2012) |
| DE (1) | DE2406198C2 (en, 2012) |
| DK (1) | DK44075A (en, 2012) |
| ES (2) | ES434546A1 (en, 2012) |
| FI (1) | FI750324A7 (en, 2012) |
| FR (1) | FR2260345B1 (en, 2012) |
| GB (1) | GB1498495A (en, 2012) |
| HU (1) | HU168482B (en, 2012) |
| IE (1) | IE40589B1 (en, 2012) |
| IL (1) | IL46593A (en, 2012) |
| LU (1) | LU71813A1 (en, 2012) |
| NL (1) | NL7501430A (en, 2012) |
| SE (1) | SE402458B (en, 2012) |
| ZA (1) | ZA75790B (en, 2012) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2210687C3 (de) * | 1972-03-06 | 1981-09-24 | Bayer Ag, 5090 Leverkusen | 2,6-Diamino-3,5-diäthoxycarbonyldihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
| JPS5232217A (en) * | 1975-09-05 | 1977-03-11 | Matsushita Electric Ind Co Ltd | Ghost eliminating equipment |
| CA1050587A (en) * | 1975-09-30 | 1979-03-13 | Fmc Corporation | Rotating gas diffuser |
| DE2738153A1 (de) * | 1977-08-24 | 1979-03-08 | Bayer Ag | 2-pyridyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| JPS57171968A (en) * | 1981-04-17 | 1982-10-22 | Kyowa Hakko Kogyo Co Ltd | 1,4-dihydropyridine derivative |
| JPS61108258U (en, 2012) * | 1984-12-21 | 1986-07-09 | ||
| JPH01181681A (ja) * | 1988-01-13 | 1989-07-19 | Komori Printing Mach Co Ltd | 印刷機のプラウ折り装置 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3887558A (en) * | 1972-03-06 | 1975-06-03 | Bayer Ag | Process for producing 2,6-diamino -1,4- dihydro-3,5-pyridine-dicarboxylates and derivatives thereof |
| DE2210687C3 (de) * | 1972-03-06 | 1981-09-24 | Bayer Ag, 5090 Leverkusen | 2,6-Diamino-3,5-diäthoxycarbonyldihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
-
1974
- 1974-02-09 DE DE2406198A patent/DE2406198C2/de not_active Expired
-
1975
- 1975-01-29 US US05/545,202 patent/US4004014A/en not_active Expired - Lifetime
- 1975-02-04 CA CA219,375A patent/CA1032539A/en not_active Expired
- 1975-02-06 BE BE153108A patent/BE825245A/xx not_active IP Right Cessation
- 1975-02-06 FI FI750324A patent/FI750324A7/fi not_active Application Discontinuation
- 1975-02-06 NL NL7501430A patent/NL7501430A/xx not_active Application Discontinuation
- 1975-02-07 JP JP50015500A patent/JPS5943460B2/ja not_active Expired
- 1975-02-07 SE SE7501388A patent/SE402458B/xx unknown
- 1975-02-07 DD DD184073A patent/DD117452A5/xx unknown
- 1975-02-07 ES ES434546A patent/ES434546A1/es not_active Expired
- 1975-02-07 FR FR7503895A patent/FR2260345B1/fr not_active Expired
- 1975-02-07 LU LU71813A patent/LU71813A1/xx unknown
- 1975-02-07 IE IE247/75A patent/IE40589B1/xx unknown
- 1975-02-07 IL IL46593A patent/IL46593A/en unknown
- 1975-02-07 ES ES434545A patent/ES434545A1/es not_active Expired
- 1975-02-07 DK DK44075*#A patent/DK44075A/da unknown
- 1975-02-07 CH CH150675A patent/CH605754A5/xx not_active IP Right Cessation
- 1975-02-07 ZA ZA00750790A patent/ZA75790B/xx unknown
- 1975-02-07 GB GB5312/75A patent/GB1498495A/en not_active Expired
- 1975-02-07 CH CH1631577A patent/CH613446A5/xx not_active IP Right Cessation
- 1975-02-07 HU HUBA3201A patent/HU168482B/hu unknown
- 1975-02-10 AT AT96975A patent/AT342590B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES434546A1 (es) | 1977-04-01 |
| NL7501430A (nl) | 1975-08-12 |
| CH605754A5 (en, 2012) | 1978-10-13 |
| DE2406198A1 (de) | 1975-08-14 |
| DE2406198C2 (de) | 1983-12-15 |
| IL46593A (en) | 1977-11-30 |
| FI750324A7 (en, 2012) | 1975-08-10 |
| SE402458B (sv) | 1978-07-03 |
| CA1032539A (en) | 1978-06-06 |
| ES434545A1 (es) | 1976-12-16 |
| SE7501388L (en, 2012) | 1975-08-11 |
| HU168482B (en, 2012) | 1976-05-28 |
| US4004014A (en) | 1977-01-18 |
| FR2260345A1 (en, 2012) | 1975-09-05 |
| DK44075A (en, 2012) | 1975-10-06 |
| DD117452A5 (en, 2012) | 1976-01-12 |
| JPS5943460B2 (ja) | 1984-10-22 |
| BE825245A (fr) | 1975-08-06 |
| IL46593A0 (en) | 1975-04-25 |
| JPS50108268A (en, 2012) | 1975-08-26 |
| IE40589B1 (en) | 1979-07-04 |
| AU7786375A (en) | 1976-08-05 |
| LU71813A1 (en, 2012) | 1975-12-09 |
| ZA75790B (en) | 1976-02-25 |
| ATA96975A (de) | 1977-08-15 |
| CH613446A5 (en, 2012) | 1979-09-28 |
| FR2260345B1 (en, 2012) | 1980-01-11 |
| IE40589L (en) | 1975-08-09 |
| AT342590B (de) | 1978-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE36265B1 (en) | New esters their production and their medicinal use | |
| GB1173104A (en) | 0,4-Dihydropyridine Derivatives and their production | |
| IE37538L (en) | 1, 4-dihydropyridine carboxylic acid compounds | |
| GB1424170A (en) | Cyclopropanecarboxylates processes for producing them and compositions containing them | |
| GB1498495A (en) | 2-amino-6-tertiary aminodihydropyridines their production and their medicinal use | |
| GB1196229A (en) | Improvements in or relating to a New Glyoxylic Acid Salt, process for its preparation and Therapeutical Composition containing same | |
| ES481715A1 (es) | Procedimiento para la obtencion de indolalquilaminas. | |
| GB1351024A (en) | Thiocetamide derivatives and preparation thereof | |
| GB1391139A (en) | Berbine derivatives and a process for producing the same | |
| IE38141B1 (en) | New 3,4-dihydropyridones their production and their medicinal use | |
| GB1352245A (en) | Azabicyclo-3.3.1-nonan-3-ol ester derivatives | |
| GB1361886A (en) | N-formyl-dl-homocysteine thiolactone and its use as a drug | |
| JPS57175164A (en) | 1,4-dihydropyridine derivative and its preparation | |
| GB1367743A (en) | 2,4,5-trisubstituted oxazoles and pharmaceutical uses thereof | |
| BE785929A (fr) | Nouveaux esters d'acides phosphoriques organiques, leur preparation et leur application comme insecticides et nematicides | |
| GB1116775A (en) | ªß-hydroxy-acrylic acid derivatives and process for their manufacture | |
| SE7513126L (sv) | Nya kvevehaltiga, polycykliska foreningar jemte sett for deras framstellning | |
| GB1306558A (en) | Derivatives of thiazolino-pyrimidin-5-ones their preparation and applications | |
| GB1384523A (en) | Oxime derivatives and their preparation | |
| ES367158A1 (es) | Procedimiento para la preparacion de 3-fenil-imidazo-tia- zol. | |
| GB1311460A (en) | 2-acryloyl benzimidazoles their process for preparation and their therapeutic application | |
| GB1336983A (en) | Sulphonyl-ureas and sulphonyl-semicarbazides | |
| GB1444879A (en) | 3-acylamino-6-amino-3,4-dihydro-2-pyridones and their use as medicaments | |
| GB1477996A (en) | Quinolizine derivatives and their preparation | |
| GB1380754A (en) | Pharmaceutical compositions comprising semi-esters of dicarboxylic acids |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |