IE40589B1 - New 2-amino-6-tertiaryaminodihydropyridines, their production and their medicinal use - Google Patents
New 2-amino-6-tertiaryaminodihydropyridines, their production and their medicinal useInfo
- Publication number
- IE40589B1 IE40589B1 IE247/75A IE24775A IE40589B1 IE 40589 B1 IE40589 B1 IE 40589B1 IE 247/75 A IE247/75 A IE 247/75A IE 24775 A IE24775 A IE 24775A IE 40589 B1 IE40589 B1 IE 40589B1
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- effect
- amino
- alkenyl
- branched
- Prior art date
Links
- 230000000694 effects Effects 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 239000000812 cholinergic antagonist Substances 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003440 anti-fibrillation Effects 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005956 isoquinolyl group Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 125000005493 quinolyl group Chemical group 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2406198A DE2406198C2 (de) | 1974-02-09 | 1974-02-09 | Verfahren zur Herstellung von neuen 2-Amino-6-dialkylamino-dihydropyridinen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40589L IE40589L (en) | 1975-08-09 |
| IE40589B1 true IE40589B1 (en) | 1979-07-04 |
Family
ID=5906982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE247/75A IE40589B1 (en) | 1974-02-09 | 1975-02-07 | New 2-amino-6-tertiaryaminodihydropyridines, their production and their medicinal use |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4004014A (en, 2012) |
| JP (1) | JPS5943460B2 (en, 2012) |
| AT (1) | AT342590B (en, 2012) |
| BE (1) | BE825245A (en, 2012) |
| CA (1) | CA1032539A (en, 2012) |
| CH (2) | CH605754A5 (en, 2012) |
| DD (1) | DD117452A5 (en, 2012) |
| DE (1) | DE2406198C2 (en, 2012) |
| DK (1) | DK44075A (en, 2012) |
| ES (2) | ES434546A1 (en, 2012) |
| FI (1) | FI750324A7 (en, 2012) |
| FR (1) | FR2260345B1 (en, 2012) |
| GB (1) | GB1498495A (en, 2012) |
| HU (1) | HU168482B (en, 2012) |
| IE (1) | IE40589B1 (en, 2012) |
| IL (1) | IL46593A (en, 2012) |
| LU (1) | LU71813A1 (en, 2012) |
| NL (1) | NL7501430A (en, 2012) |
| SE (1) | SE402458B (en, 2012) |
| ZA (1) | ZA75790B (en, 2012) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2210687C3 (de) * | 1972-03-06 | 1981-09-24 | Bayer Ag, 5090 Leverkusen | 2,6-Diamino-3,5-diäthoxycarbonyldihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
| JPS5232217A (en) * | 1975-09-05 | 1977-03-11 | Matsushita Electric Ind Co Ltd | Ghost eliminating equipment |
| CA1050587A (en) * | 1975-09-30 | 1979-03-13 | Fmc Corporation | Rotating gas diffuser |
| DE2738153A1 (de) * | 1977-08-24 | 1979-03-08 | Bayer Ag | 2-pyridyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| JPS57171968A (en) * | 1981-04-17 | 1982-10-22 | Kyowa Hakko Kogyo Co Ltd | 1,4-dihydropyridine derivative |
| JPS61108258U (en, 2012) * | 1984-12-21 | 1986-07-09 | ||
| JPH01181681A (ja) * | 1988-01-13 | 1989-07-19 | Komori Printing Mach Co Ltd | 印刷機のプラウ折り装置 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3887558A (en) * | 1972-03-06 | 1975-06-03 | Bayer Ag | Process for producing 2,6-diamino -1,4- dihydro-3,5-pyridine-dicarboxylates and derivatives thereof |
| DE2210687C3 (de) * | 1972-03-06 | 1981-09-24 | Bayer Ag, 5090 Leverkusen | 2,6-Diamino-3,5-diäthoxycarbonyldihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
-
1974
- 1974-02-09 DE DE2406198A patent/DE2406198C2/de not_active Expired
-
1975
- 1975-01-29 US US05/545,202 patent/US4004014A/en not_active Expired - Lifetime
- 1975-02-04 CA CA219,375A patent/CA1032539A/en not_active Expired
- 1975-02-06 BE BE153108A patent/BE825245A/xx not_active IP Right Cessation
- 1975-02-06 FI FI750324A patent/FI750324A7/fi not_active Application Discontinuation
- 1975-02-06 NL NL7501430A patent/NL7501430A/xx not_active Application Discontinuation
- 1975-02-07 JP JP50015500A patent/JPS5943460B2/ja not_active Expired
- 1975-02-07 SE SE7501388A patent/SE402458B/xx unknown
- 1975-02-07 DD DD184073A patent/DD117452A5/xx unknown
- 1975-02-07 ES ES434546A patent/ES434546A1/es not_active Expired
- 1975-02-07 FR FR7503895A patent/FR2260345B1/fr not_active Expired
- 1975-02-07 LU LU71813A patent/LU71813A1/xx unknown
- 1975-02-07 IE IE247/75A patent/IE40589B1/xx unknown
- 1975-02-07 IL IL46593A patent/IL46593A/en unknown
- 1975-02-07 ES ES434545A patent/ES434545A1/es not_active Expired
- 1975-02-07 DK DK44075*#A patent/DK44075A/da unknown
- 1975-02-07 CH CH150675A patent/CH605754A5/xx not_active IP Right Cessation
- 1975-02-07 ZA ZA00750790A patent/ZA75790B/xx unknown
- 1975-02-07 GB GB5312/75A patent/GB1498495A/en not_active Expired
- 1975-02-07 CH CH1631577A patent/CH613446A5/xx not_active IP Right Cessation
- 1975-02-07 HU HUBA3201A patent/HU168482B/hu unknown
- 1975-02-10 AT AT96975A patent/AT342590B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES434546A1 (es) | 1977-04-01 |
| NL7501430A (nl) | 1975-08-12 |
| CH605754A5 (en, 2012) | 1978-10-13 |
| DE2406198A1 (de) | 1975-08-14 |
| DE2406198C2 (de) | 1983-12-15 |
| IL46593A (en) | 1977-11-30 |
| FI750324A7 (en, 2012) | 1975-08-10 |
| SE402458B (sv) | 1978-07-03 |
| CA1032539A (en) | 1978-06-06 |
| ES434545A1 (es) | 1976-12-16 |
| SE7501388L (en, 2012) | 1975-08-11 |
| HU168482B (en, 2012) | 1976-05-28 |
| US4004014A (en) | 1977-01-18 |
| FR2260345A1 (en, 2012) | 1975-09-05 |
| DK44075A (en, 2012) | 1975-10-06 |
| GB1498495A (en) | 1978-01-18 |
| DD117452A5 (en, 2012) | 1976-01-12 |
| JPS5943460B2 (ja) | 1984-10-22 |
| BE825245A (fr) | 1975-08-06 |
| IL46593A0 (en) | 1975-04-25 |
| JPS50108268A (en, 2012) | 1975-08-26 |
| AU7786375A (en) | 1976-08-05 |
| LU71813A1 (en, 2012) | 1975-12-09 |
| ZA75790B (en) | 1976-02-25 |
| ATA96975A (de) | 1977-08-15 |
| CH613446A5 (en, 2012) | 1979-09-28 |
| FR2260345B1 (en, 2012) | 1980-01-11 |
| IE40589L (en) | 1975-08-09 |
| AT342590B (de) | 1978-04-10 |
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