GB1496940A - Process for producing l-leucine - Google Patents
Process for producing l-leucineInfo
- Publication number
- GB1496940A GB1496940A GB10474/75A GB1047475A GB1496940A GB 1496940 A GB1496940 A GB 1496940A GB 10474/75 A GB10474/75 A GB 10474/75A GB 1047475 A GB1047475 A GB 1047475A GB 1496940 A GB1496940 A GB 1496940A
- Authority
- GB
- United Kingdom
- Prior art keywords
- leucine
- producing
- march
- accumulated
- microorganisms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 title abstract 10
- 238000000034 method Methods 0.000 title abstract 2
- 229960003136 leucine Drugs 0.000 abstract 5
- 239000004395 L-leucine Substances 0.000 abstract 3
- 235000019454 L-leucine Nutrition 0.000 abstract 3
- 244000005700 microbiome Species 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 241000186226 Corynebacterium glutamicum Species 0.000 abstract 2
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 abstract 2
- 235000015097 nutrients Nutrition 0.000 abstract 2
- YYAYLSOQGBAUHK-UHFFFAOYSA-N 2-(1,3-thiazol-2-ylamino)propanoic acid Chemical compound OC(=O)C(C)NC1=NC=CS1 YYAYLSOQGBAUHK-UHFFFAOYSA-N 0.000 abstract 1
- QWCKQJZIFLGMSD-UHFFFAOYSA-N 2-Aminobutanoic acid Natural products CCC(N)C(O)=O QWCKQJZIFLGMSD-UHFFFAOYSA-N 0.000 abstract 1
- MBZXSJWDBIIBLL-UHFFFAOYSA-N 2-amino-4-methylhexanoic acid Chemical compound CCC(C)CC(N)C(O)=O MBZXSJWDBIIBLL-UHFFFAOYSA-N 0.000 abstract 1
- -1 4- thiaisoleucine Chemical compound 0.000 abstract 1
- XFGVJLGVINCWDP-UHFFFAOYSA-N 5,5,5-trifluoroleucine Chemical compound FC(F)(F)C(C)CC(N)C(O)=O XFGVJLGVINCWDP-UHFFFAOYSA-N 0.000 abstract 1
- 241000186146 Brevibacterium Species 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 241000186216 Corynebacterium Species 0.000 abstract 1
- QWCKQJZIFLGMSD-GSVOUGTGSA-N D-alpha-aminobutyric acid Chemical compound CC[C@@H](N)C(O)=O QWCKQJZIFLGMSD-GSVOUGTGSA-N 0.000 abstract 1
- DKEXFJVMVGETOO-LURJTMIESA-N Gly-Leu Chemical compound CC(C)C[C@@H](C(O)=O)NC(=O)CN DKEXFJVMVGETOO-LURJTMIESA-N 0.000 abstract 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 abstract 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 108010050848 glycylleucine Proteins 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 229960000310 isoleucine Drugs 0.000 abstract 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 abstract 1
- 150000002614 leucines Chemical class 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/84—Brevibacterium
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/843—Corynebacterium
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2964574A JPS579796B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-03-15 | 1974-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1496940A true GB1496940A (en) | 1978-01-05 |
Family
ID=12281820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB10474/75A Expired GB1496940A (en) | 1974-03-15 | 1975-03-13 | Process for producing l-leucine |
Country Status (6)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5626196A (en) * | 1979-08-10 | 1981-03-13 | Mitsubishi Petrochem Co Ltd | Preparation of l-aspartic acid |
| US4421853A (en) * | 1982-06-16 | 1983-12-20 | W. R. Grace & Co. | Fermentative preparation of L-leucine |
| US4421854A (en) * | 1982-06-16 | 1983-12-20 | W. R. Grace & Co. | Fermentative preparation of L-leucine |
| US5032681A (en) * | 1987-03-06 | 1991-07-16 | Massachusetts Institute Of Technology | LEU3 gene sequence of S. cerevisiae and use in regulation of amino acid synthesis |
| US4870159A (en) * | 1987-03-06 | 1989-09-26 | Massachusetts Institute Of Technology | LEU3 gene sequence of S. cerevisiae and use in regulation of amino acid synthesis |
| RU2140450C1 (ru) * | 1997-10-29 | 1999-10-27 | Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") | Штамм бактерий escherichia coli продуцент l-лейцина (варианты) |
| RU2201454C2 (ru) * | 1999-07-09 | 2003-03-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Мутантная альфа-изопропилмалат синтаза (ipms), днк, кодирующая мутантную ipms, способ получения штамма escherichia coli, способ получения l-лейцина |
| MXPA02001174A (es) * | 1999-08-02 | 2002-07-30 | Archer Daniels Midland Co | Ingenieria metabolica de la produccion de aminoacidos. |
| KR101117022B1 (ko) * | 2011-08-16 | 2012-03-16 | 씨제이제일제당 (주) | Ｌ-발린 생산능이 향상된 미생물 및 이를 이용한 ｌ-발린 제조방법 |
| WO2013160124A1 (en) * | 2012-04-27 | 2013-10-31 | Evonik Industries Ag | Feedback-resistant alpha-isopropylmalate synthases |
| EP3053999B1 (en) | 2013-10-02 | 2019-11-20 | Ajinomoto Co., Inc. | Ammonia control apparatus and ammonia control method |
| EP3716274A1 (en) | 2019-03-29 | 2020-09-30 | Ajinomoto Co., Inc. | Control device, control method, computer program, and method for producing organic compound |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1900492A1 (de) * | 1968-01-11 | 1970-09-17 | Kyowa Hakko Kogyo Kk | Herstellung von 1-Leucin durch Fermentation |
| US3865690A (en) * | 1969-11-06 | 1975-02-11 | Ajinomoto Kk | Fermentative production of L-leucine |
-
1974
- 1974-03-15 JP JP2964574A patent/JPS579796B2/ja not_active Expired
-
1975
- 1975-02-27 IT IT20726/75A patent/IT1033255B/it active
- 1975-03-04 US US05/555,114 patent/US3970519A/en not_active Expired - Lifetime
- 1975-03-13 GB GB10474/75A patent/GB1496940A/en not_active Expired
- 1975-03-14 FR FR7508139A patent/FR2264088B1/fr not_active Expired
- 1975-03-14 CA CA222,113A patent/CA1046440A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IT1033255B (it) | 1979-07-10 |
| JPS579796B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1982-02-23 |
| JPS50123877A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-09-29 |
| FR2264088A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-10-10 |
| CA1046440A (en) | 1979-01-16 |
| FR2264088B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-08-18 |
| US3970519A (en) | 1976-07-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3708395A (en) | Process for producing l-lysine | |
| GB1258380A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| US3660235A (en) | Method for producing phenylalanine by fermentation | |
| KR890014748A (ko) | 아미노산의 제조방법 | |
| GB1417067A (en) | Biological process for producing derivatives of amino acids | |
| GB1496940A (en) | Process for producing l-leucine | |
| US4224409A (en) | Method for producing L-proline by fermentation | |
| GB1342308A (en) | Production of threonine and lysine by fermentation | |
| US3865690A (en) | Fermentative production of L-leucine | |
| KR920006507A (ko) | L-발린의 제조방법 | |
| GB1433294A (en) | Fermentative production of l-valine | |
| US3871960A (en) | Method of producing l-lysine by fermentation | |
| GB1338434A (en) | Process for producing l-methionine | |
| GB1276604A (en) | Process for producing tryptophan by fermentation | |
| GB1118719A (en) | Process for producing l-lysine by fermentation | |
| US3843441A (en) | Method of producing l-serine by fermentation | |
| GB1431593A (en) | Amino acid production | |
| US3595751A (en) | Process for producing l-lysine | |
| US4403033A (en) | Method for producing L-phenylalanine by fermentation | |
| US3787287A (en) | Process for the production of l-tyrosine | |
| GB1316888A (en) | Process for producing l-isoluecine by fermentation | |
| GB1490008A (en) | Method for producing l-aspartic acid by fermentation | |
| GB1353780A (en) | Process for the microbial production of lysine and isoleucine | |
| GB1422820A (en) | Method for producing l-serine | |
| GB1259444A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19940313 |